Extension of the selection of protein chromatography and the rate model to affinity chromatography

Journal of Molecular Recognition

Volumn 23, Issue 6, 2010, Pages 609-617

  Sandoval, G ^a   Shene, C ^b   Andrews, B A ^a   Asenjo, J A ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSIDAD DE LA FRONTERA   (Chile)

Author keywords

Affinity chromatography; Mathematical; Modelling; Rational selection

Indexed keywords

BLUE SEPHAROSE; BLUE-SEPHAROSE; DRUG DERIVATIVE; INORGANIC SALT; PROTEIN; SEPHAROSE;

AFFINITY CHROMATOGRAPHY; ALGORITHM; ARTICLE; CHEMISTRY; CHROMATOGRAPHY; COMPUTER SIMULATION; DECISION MAKING; DECISION SUPPORT SYSTEM; EXPERT SYSTEM; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; OSMOLARITY; PRODUCTIVITY; PROTEOMICS; THEORETICAL MODEL; UTILIZATION REVIEW;

ALGORITHMS; CHOICE BEHAVIOR; CHROMATOGRAPHY; CHROMATOGRAPHY, AFFINITY; COMPUTER SIMULATION; DECISION SUPPORT TECHNIQUES; EFFICIENCY; EXPERT SYSTEMS; MODELS, THEORETICAL; OSMOLAR CONCENTRATION; PROTEINS; PROTEOMICS; SALTS; SEPHAROSE;

EID: 78049435715     PISSN: 09523499     EISSN: 10991352     Source Type: Journal    
DOI: 10.1002/jmr.1088     Document Type: Article

References (11)

1. Asenjo, JA. 1990. Selection of operations in separation processes. In Separation Processes in Biotechnology, Asenjo JA (ed.) Marcel Dekker: New York; 3-16.
2. Asenjo, JA Andrews, BA. 2004. Is there a rational method to purify proteins?: from expert systems to proteomics. J. Mol. Recognit. 17: 236-247.
3. Carroll, DL. 2009. D. L. Carroll's FORTRAN Genetic Algorithm Driver, in March 2009.
4. Gu, T. 1995. Mathematical Modeling and Scale-Up of Liquid Chromatography. Berlin: Springer.
5. Lazo, C. 1999. Simulation of Liquid Chromatography and Simulated Moving Bed (SMB) Systems. Sudienarbeit Technische Universitat: Hamburg-Harburg.
6. Leser, EW. 1996. Prot_Ex: an expert system for selecting the sequence of processes for the downstream purification of proteins. Ph.D. Thesis, University of Reading.
7. Leser, EW, Asenjo, JA. 1992. The rational design of purification processes for recombinant proteins. J. Chromatogr. 584: 35-42.
8. Li, W., Zhang, S., Sun, Y. 2004. Modeling of the linear-gradient dye-ligand affinity chromatography with a binary adsorption isotherm. Biochem. Eng. J. 22: 63-70.
9. Lienqueo, ME, Leser, EW, Asenjo JA. 1996. An expert system for the selection and synthesis of multistep protein separation processes. Comput. Chem. Eng. 20: S189-S194.
10. Orellana CA., Shene C., Asenjo JA. 2009. Mathematical modeling of elution curves for a protein mixture in ion exchange chromatography applied to high protein concentration. Biotechnol. Bioeng. 104: 572-581.
11. Shene C, Lucero A, Andrews BA, Asenjo, JA. 2006. Mathematical modeling of elution curves for a protein mixture in ion exchange chromatography and for the optimal selection of operational conditions. Biotechnol. Bioeng. 95: 704-713.