Partition behavior and partition mechanism of antibiotics in ethanol/2-propanol-ammonium sulfate aqueous two-phase systems

Separation and Purification Technology

Volumn 75, Issue 3, 2010, Pages 352-357

  Wang, Yun ^a   Han, Juan ^a   Xu, Xiaohui ^a   Hu, Shiping ^a   Yan, Yongsheng ^a  

^a JIANGSU UNIVERSITY   (China)

Author keywords

Alcohol; Antibiotics; Aqueous two phase system; Salting out effect

Indexed keywords

2-PROPANOL; AMMONIUM SULFATE; AQUEOUS SOLUTIONS; AQUEOUS TWO PHASE SYSTEM; AQUEOUS TWO-PHASE EXTRACTION; DRIVING FORCES; EXTRACTION EFFICIENCIES; ISO-ELECTRIC POINTS; PARTITION BEHAVIORS; PARTITION COEFFICIENT; RICH PHASE; SALTING-OUT EFFECT; TETRACYCLINE HYDROCHLORIDE; UNDERLYING MECHANISM;

AMMONIUM COMPOUNDS; ANTIBIOTICS; ETHANOL; PHASE SEPARATION; PROPANOL; SOLUTIONS; SOLVENT EXTRACTION;

PH EFFECTS;

EID: 78049429640     PISSN: 13835866     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seppur.2010.09.004     Document Type: Article

References (15)

1. A.M. Azevedo, A.G. Gomes, P.A.J. Rosa, I.F. Ferreira, A.M.M.O. Pisco, and M.R. Aires-Barros Partitioning of human antibodies in polyethylene glycol-sodium citrate aqueous two-phase systems Sep. Purif. Technol. 65 2009 14 21
2. S. Dreyer, and U. Krag Ionic liquids for aqueous two-phase extraction and stabilization of enzymes Biotechnol. Bioeng. 99 2008 1416 1424
3. A. Frerix, P. Geilenkirchen, M. Müller, M.R. Kula, and J. Hubbuch Separation of genomic DNA, RNA, and open circular plasmid DNA from supercoiled plasmid DNA by combining denaturation, selective renaturation and aqueous two-phase extraction Biotechnol. Bioeng. 96 2007 57 66
4. F. Rahimpour, F. Feyzi, S. Maghsoudi, and R. Hatti-Kaul Purification of plasmid DNA with polymer-salt aqueous two-phase system: optimization using response surface methodology Biotechnol. Bioeng. 95 2006 627 637
5. W.Y. Yang, C.D. Lin, I.M. Chu, and C.J. Lee Extraction of cephalosporin C from whole broth and separation of desacetyl cephalosporin C by aqueous two-phase partition Biotechnol. Bioeng. 43 1994 439 445
6. M.M. Bora, S. Borthakur, P.C. Rao, and N.N. Dutta Aqueous two-phase partitioning of cephalosporin antibiotics: effect of solute chemical nature Sep. Purif. Technol. 45 2005 153 156
7. Q. Le, L. Shong, and Y. Shi Extraction of erythromycin from fermentation broth using salt-induced phase separation processes Sep. Purif. Technol. 24 2001 85 91
8. C.K. Lee, and S.I. Sandler Vancomycin partitioning in aqueous two-phase systems: effects of pH, salts, and an affinity ligand Biotechnol. Bioeng. 35 1990 408 416
9. B. Mokhtarani, R. Karimzadeh, M.H. Amini, and S.D. Manesh Partitioning of ciprofloxacin in aqueous two-phase system of poly(ethylene glycol) and sodium sulphate Biochem. Eng. J. 38 2008 241 247
10. Y. Jiang, H. Xia, J. Yu, C. Guo, and H. Liu Hydrophobic ionic liquids-assisted polymer recovery during penicillin extraction in aqueous two-phase system Chem. Eng. J. 147 2009 22 26
11. Y. Guan, Z. Zhu, and L. Mei Technical aspects of extractive purification of penicillin fermentation broth by aqueous two-phase partitioning Sep. Sci. Technol. 31 1996 2589 2597
12. Y. Jiang, H. Xia, C. Guo, I. Mahmood, and H. Liu Phenomena and mechanism for separation and recovery of penicillin in ionic liquids aqueous solution Ind. Eng. Chem. Res. 46 2007 6303 6312
13. K.E. Gutowski, G.A. Broker, H.D. Willauer, J.G. Huddleston, R.P. Swatloski, J.D. Holbrey, and R.D. Rogers Controlling the aqueous miscibility of ionic liquids: aqueous biphasic systems of water-miscible ionic liquids and water-structuring salts for recycle, metathesis, and separations J. Am. Chem. Soc. 125 2003 6632 6633
14. N.J. Bridges, K.E. Gutowski, and R.D. Rogers Investigation of aqueous biphasic systems formed from solutions of chaotropic salts with kosmotropic salts (salt-salt ABS) Green Chem. 9 2007 177 183
15. Y. Wang, Y.S. Yan, S.P. Hu, J. Han, and X.H. Xu Phase diagrams of ammonium sulfate + ethanol/1-propanol/2-propanol + water aqueous two-phase systems at 298.15 K and correlation J. Chem. Eng. Data 55 2010 876 881