Multiple brain pathologies in dementia are common

European Geriatric Medicine

Volumn 1, Issue 5, 2010, Pages 259-265

  Woodward, M ^a   MacKenzie, I R A ^b   Hsiung, G Y R ^c   Jacova, C ^c   Feldman, H ^d,e  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b VANCOUVER GENERAL HOSPITAL   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e BRISTOL MYERS SQUIBB   (United States)

Author keywords

Clinical pathological correspondence; Dementia; Dementia cohort study; Neuropathology

Indexed keywords

TAR DNA BINDING PROTEIN;

AGED; ALZHEIMER DISEASE; ARGYROPHILIA; ARTICLE; AUTOPSY; BRAIN DISEASE; CEREBROVASCULAR DISEASE; CLINICAL ARTICLE; COGNITIVE DEFECT; DEMENTIA; DIFFUSE LEWY BODY DISEASE; DISEASE SEVERITY; FEMALE; FRONTOTEMPORAL DEMENTIA; HIPPOCAMPAL SCLEROSIS; HOSPITAL; HUMAN; MALE; NEUROLOGIC EXAMINATION; NEUROPATHOLOGY; POPULATION; PROGRESSIVE SUPRANUCLEAR PALSY; PROSPECTIVE STUDY; SCORING SYSTEM; VASCULAR LESION;

EID: 78049420077     PISSN: 18787649     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurger.2010.07.012     Document Type: Article

References (58)

1. J.A. Schneider, Z. Arvanitakis, and M.S. Bang Woojeong Mixed brain pathologies account for most dementia cases in community-dwelling older persons Neurology 69 2007 2197 2204
2. M. Gearing, S.S. Mirra, and J.C. Hedreen The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathological confirmation of the clinical diagnosis of Alzheimer's disease Neurology 45 1995 461 466
3. A. Heyman, G.G. Fillenbaum, and K.A. Welsh-Bohmer Cerebral infarcts in patients with autopsy-proven Alzheimer's disease: CERAD, part XV111 Neurology 51 1998 159 162
4. D.A. Snowdon, L.H. Greiner, and J.A. Mortimer Brain infarction and the clinical expression of Alzheimer's disease: the Nun Study JAMA 227 1997 813 817
5. D. Zekry, J.J. Hauw, and G. Gold Mixed dementia: epidemiology, diagnosis and treatment J Am Geriatr Soc 50 2002 1431 1438
6. R.G. Riekse, J.B. Leverenz, and W. McCormick Effect of vascular lesions on cognition in Alzheimer's disease: a community-based study J Am Geriatr Soc 52 2004 1442 1448
7. C.F. Lindboe, and H.B. Hansen The frequency of Lewy bodies in a consecutive autopsy series Clin Neuropathol 17 1998 204 209
8. E. Londos, U. Passant, and L. Gustafsson Neuropathological correlates to clinically defined dementia with Lewy bodies Int J Geriatr Psychiatry 16 2001 667 679
9. M.L. Kraybill, E.B. Larson, and D.W. Tsuang Cognitive differences in dementia patients with autopsy-verified AD, Lewy body pathology, or both Neurology 64 2005 2069 2073
10. W. Samuel, M. Alford, and C.R. Hofstetter Dementia with Lewy bodies versus pure Alzheimer's disease: differences in cognition, neuropathology, cholinergic dysfunction and synapse density J Neuropath Exp Neurol 56 1997 499 508
11. C. Amador-Ortiz, W.L. Lin, and Z. Ahmed TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease Ann Neurol 61 2007 435 445
12. T. Arai, I.R.A. Mackenzie, and M. Hasegawa Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies Acta Neuropathol 117 2009 125 136
13. S. Higashi, E. Iseki, and R. Yamamoto Concurrence of TDP-43, tau and α-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies Brain Res 1184 2007 284 294
14. H. Nakashima-Yasuda, K. Uryu, and J. Robinson Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases Acta Neuropathol (Berl) 114 2007 221 229
15. K. Uryu, H. Nakashima-Yasuda, and M.S. Forman Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies J Neuropathol Exp Neurol 67 2008 555 564
16. I.R.A. Mackenzie, M. Neumann, and E.H. Bigio Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations Acta Neuropathol 117 2009 15 18
17. K.A. Josephs, J.L. Whitwell, and D.S. Knopman Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype Neurology 70 2008 1850 1857
18. D.R. Thal, C. Schultz, and G. Botez The impact of argyrophilic grain disease on the development of dementia and its relationship to concurrent Alzheimer's disease- related pathology Neuropath Applied Neurobiol 31 2005 270 279
19. H. Feldman, A.R. Levy, and G.Y. Hsiung A Canadian Cohort Study of Cognitive Impairment and Related Dementias (ACCORD): study methods and baseline results Neuroepidemiology 22 2003 265 274
20. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-IIIR). American Psychiatric Association. Washington, DC. 1987.
21. G. McKhann, D. Drachman, and M. Folstein Clinical diagnosis of Alzheimer's disease Report of the NINCDS-ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease Neurology. 34 1984 939 944
22. Lund and Manchester Groups (1994). Clinical and neuropathological criteria for frontotemporal dementia. J Neurol Neurosurg Psychiatry 1994;57:416-8.
23. I.G. McKeith, D. Galasko, and K. Kosaka Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop Neurology 47 1996 1113 1124
24. S.S. Mirra, A. Heyman, and D. McKeel The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) Part II. Standardization of the neuropathologic assessment of Alzheimer's disease Neurology 41 1991 479 486
25. The National Institute on Aging and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease. Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. Neurobiol Aging 1997;18(Suppl. 4):S1-S2.
26. D.G. Munoz The pathological basis of multi-infarct dementia Alz Dis Assoc Disord 5 1991 77 90
27. M. Jackson, G. Lennox, and J. Lowe Motor neurone disease-inclusion dementia Neurodegeneration 5 1996 339 350
28. M. Neumann, D.M. Sampathu, and L.K. Kwong Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Science 314 2006 130 133
29. J.J. Hauw, S.E. Daniel, and D. Dickson Preliminary NINDS neuropathologic criteria for Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy) Neurology 44 1994 2015 2019
30. D.W. Dickson, C. Bergeron, and S.S. Chin Office of rare diseases neuropathologic criteria for corticobasal degeneration J Neuropathol Exp Neurol 61 2002 935 946
31. D.W. Dickson Pick's disease: a modern approach Brain Pathol 8 1998 339 354
32. D.W. Dickson Neuropathologic differentiation of progressive supranuclear palsy and corticobasal degeneration J Neurol 246 Suppl. 2 1999 6 15
33. H. Braak, and E. Braak Cortical and subcortical argyrophilic grains characterize a disease associated with adult onset dementia Neuropathol Appl Neurobiol 15 1989 13 26
34. P. Martinez-Lage, and D.G. Munoz Prevalence and disease association of argyrophilic grains of Braak J Neuropathol Exp Neurol 56 1997 157 164
35. M. Tolnay, A.U. Monsch, and A. Probst Argyrophilic grain disease: a frequent dementing disorder in aged patients Adv Exp Med Biol 487 2001 39 58
36. B.L. Plassman, A.S. Khachaturian, and J.L. Townsend Comparison of the clinical and neuropathologic diagnoses of Alzheimer's disease in 3 epidemiological samples Alzheimer Dement 2 2006 2 11
37. L. White, B.J. Small, and H. Petrovitch Recent clinico-pathologic research on the causes of dementia in later life: update for the Honolulu-Asia Aging Study J Geriatr Psychiatry Neurol 18 2005 224 227
38. Neuropathology Group of the Medical Research Council Cognitive Function and Aging Study (MRC CFAS). Pathologic correlates of late onset dementia in a multicentre, community based population in England and Wales. Lancet 2001;357:169-75.
39. Y. Wakisaka, A. Furata, and Y. Tanizaki Age- associated prevalence and risk factors of Lewy body pathology in a general population: the Hisayama study Acta Neuropathol (Berl) 106 2003 374 382
40. J.A. Schneider, Z. Arvanitakis, and S.E. Leurgans The neuropathology of probable Alzheimer disease and mild cognitive impairment Ann Neurol 66 2009 200 208
41. A. Lim, D. Tsuang, and W. Kukull Clinico-pathological correlation of Alzheimer's disease in a community-based case series J Am Geriatr Soc 47 1999 564 569
42. G. Gold, P. Giannakopoulos, F.R. Herrmann, C. Bouras, and E. Kövari Identification of Alzheimer and vascular lesion thresholds for mixed dementia Brain 130 2007 2830 2836
43. M. Mesulam, A. Wicklund, and N. Johnson Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia Ann Neurol 63 2008 709 719
44. A. Kertesz, P. McMonagle, and M. Blair The evolution and pathology of frontotemporal dementia Brain 128 2005 1996 2005
45. M.S. Forman, J. Farmer, and J.K. Johnson Frontotemporal dementia: clinicopathological correlates Ann Neurol 59 2006 952 962
46. M.C. Woodward, C. Jacova, and I.R. Mackenzie Int J Geriatr Psychiatry 25 2010 732 738
47. G.M. Savva, S.B. Wharton, and P.C. Ince Age, neuropathology and dementia N Engl J Med 360 2009 2302 2309
48. J. Victoroff, W.J. Mack, and S.A. Lyness Multicentre clinicopathological correlation in dementia Am J Psychiatry 152 1995 1476 1484
49. I.G. McKeith, D.W. Dickson, and J. Lowe Diagnosis and management of dementia with Lewy bodies. Third report of the DLB consortium Neurology 65 2005 1863 1872
50. M. Grossman, J. Farmer, and S. Leight Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease Ann Neurol 57 2005 721 729 (Pubitemid 40628861)
51. N.S.M. Schoonenboom, Y.A.L. Pijnenburg, and C. Mulder Amyloid [beta] (1-42) and phosphorylated tau in CSF as markers for early- onset Alzheimer's disease Neurology 62 2004 1580 1584
52. E. Kapaki, G.P. Paraskevas, and S.G. Papageorgiou Diagnostic value of CSF biomarker profile in frontotemporal lobar degeneration Alzheimer Dis Assoc Disord 22 2008 47 53
53. 1H MR spectroscopy in common dementias Neurology 63 2004 1393 1398
54. C.C. Rowe, S. Ng, and U. Ackermann Imaging β-amyloid burden in aging and dementia Neurology 68 2007 1718 1725
55. W. Jagust Positron emission tomography and magnetic resonance imaging in the diagnosis and prediction of dementia Alzheimer Dement 2 2006 36 42
56. G.D. Rabinovici, A.J. Furst, and J.P. O'Neil 11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration Neurology 68 2007 1205 1212
57. 18F-fluorodopa PET study of striatal dopamine uptake in the diagnosis of dementia with Lewy bodies Neurology 55 2000 1575 1577
58. 18F-FDG PET measures in differentiating dementias J Nuc Med 46 2005 936 944