Why do intensivists still use hydroxyethyl starch?

Critical Care Medicine

Volumn 38, Issue 11, 2010, Pages 2260-2262

  Kellum, John A ^a   James, Michael F M ^b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

acute kidney injury (AKI); colloids; fluid resuscitation; Hydroxyethyl starch (HES); volume expansion

Indexed keywords

HETASTARCH; HUMAN ALBUMIN; ISOTONIC SOLUTION; VASOACTIVE AGENT; ORAL REHYDRATION SOLUTION; PLASMA SUBSTITUTE;

BLOOD GLUCOSE MONITORING; COST EFFECTIVENESS ANALYSIS; EDITORIAL; FACTORIAL DESIGN; FLUID RESUSCITATION; HOSPITALIZATION; HUMAN; INTENSIVE CARE; INTENSIVE CARE UNIT; KIDNEY INJURY; LUNG CAPILLARY PRESSURE; MOLECULAR WEIGHT; PRIORITY JOURNAL; RENAL REPLACEMENT THERAPY; RISK FACTOR; COLLOID; FLUID THERAPY; HEART SURGERY; METHODOLOGY; NOTE; POSTOPERATIVE CARE;

CARDIAC SURGICAL PROCEDURES; COLLOIDS; FLUID THERAPY; HETASTARCH; HUMANS; PLASMA SUBSTITUTES; POSTOPERATIVE CARE; REHYDRATION SOLUTIONS;

EID: 78049415090     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181f8fa15     Document Type: Editorial

References (17)

1. Kozek-Langenecker SA: Effects of hydroxyethyl starch solutions on hemostasis. Anesthesiology 2005;103:654-660
2. Dickenmann M, Oettl T, Mihatsch MJ: Osmotic nephrosis: Acute kidney injury with accumulation of proximal tubular lysosomes due to administration of exogenous solutes. Am J Kidney Dis 2008;51:491-503
3. Ertmer C, Rehberg S, Van Aken H, et al: Relevance of non-albumin colloids in intensive care medicine. Best Pract Res Clin Anaesthesiol 2009;23:193-212
4. Schortgen F, Lacherade JC, Bruneel F, et al: Effects of hydroxyethylstarch and gelatin on renal function in severe sepsis: A multicentre randomised study. Lancet 2001;357:911-916
5. Brunkhorst FM, Engel C, Bloos F, et al: Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 2008;358:125-139
6. Eisenbach C, Schonfeld AH, Vogt N, et al: Pharmacodynamics and organ storage of hydroxyethyl starch in acute hemodilution in pigs: Influence of molecular weight and degree of substitution. Intensive Care Med 2007;33:1637-1644
7. Thomas G, Balk EM, Jaber BL: Effect of intensive insulin therapy and pentastarch resuscitation on acute kidney injury in severe sepsis. Am J Kidney Dis 2008;52:13-17
8. Boldt J, Brosch C, Ducke M, et al: Influence of volume therapy with a modern hydroxyethylstarch preparation on kidney function in cardiac surgery patients with compromised renal function: A comparison with human albumin. Crit Care Med 2007;35:2740-2746
9. Wiedermann CJ: Systematic review of randomized clinical trials on the use of hydroxyethyl starch for fluid management in sepsis. BMC Emerg Med 2008;8:1
10. Sakr Y, Payen D, Reinhart K, et al: Effects of hydroxyethyl starch administration on renal function in critically ill patients. Br J Anaesth 2007;98:216-224
11. Finfer S, Bellomo R, Boyce N, et al: A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 2004;350:2247-2256
12. Perel P, Roberts I: Colloids versus crystalloids for fluid resuscitation in critically ill patients. Cochrane Database Systc Rev 2007;4:CD000567
13. Wiedemann HP, Wheeler AP, Bernard GR, et al: Comparison of two fluid-management strategies in acute lung injury. N Engl J Med 2006;354:2564-2575
14. Bouchard J, Soroko SB, Chertow GM, et al: Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury. Kidney Int 2009;76:422-427
15. Magder S, Potter BJ, De Varennes B, et al: Fluids after cardiac surgery: A pilot study of the use of colloids versus crystalloids. Crit Care Med 2010;38:2117-2124
16. Arellano R, Gan BS, Salpeter MJ, et al: A triple-blinded randomized trial comparing the hemostatic effects of large-dose 10% hydroxyethyl starch 264/0.45 versus 5% albumin during major reconstructive surgery. Anesth Analg 2005;100:1853
17. Osman D, Ridel C, Ray P, et al: Cardiac filling pressures are not appropriate to predict hemodynamic response to volume challenge. Crit Care Med 2007;35:64-68