Signaling from fibroblast growth factor receptor 2 in immature hematopoietic cells facilitates donor hematopoiesis after intra-bone marrow-bone marrow transplantation

Stem Cells and Development

Volumn 19, Issue 11, 2010, Pages 1679-1686

  Shigematsu, Akio ^a,b   Shi, Ming ^a   Okigaki, Mitsuhiko ^c   Adachi, Yasushi ^a   Koike, Naoko ^a   Che, Jishan ^c   Iwasaki, Masayoshi ^a   Matsubara, Hiroaki ^c   Imamura, Masahiro ^b   Ikehara, Susumu ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KYOTO PREFECTURAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN RECEPTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL COUNT; CELL CULTURE; CELL LINEAGE; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; COLONY FORMING UNIT; CONTROLLED STUDY; HEMATOPOIESIS; HEMATOPOIETIC CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; ANTIGENS, LY; BONE MARROW TRANSPLANTATION; CELL LINEAGE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; RNA, MESSENGER; SIGNAL TRANSDUCTION;

MUS;

EID: 78049363036     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2009.0370     Document Type: Article

References (38)

1. Basilico C and D Moscatelli. (1992). The FGF family of growth factors and oncogenes. Adv Cancer Res 59:115-165.
2. Baird A. (1994). Fibroblast growth factors: activities and significance of non-neurotrophin neurotrophic growth factors. Curr Opin Neurobiol 4:78-86.
3. Krejci P, J Prochazkova, V Bryja, A Kozubik and WR Wilcox. (2009). Molecular pathology of the fibroblast growth factor family. Hum Mutat 30:1245-1255.
4. Fischer S, BW Draper and CJ Neumann (2003). The zebrafish fgf24 mutant identifies an additional level of Fgf signaling involved in vertebrate forelimb initiation. Development 130, 3515-3524.
5. Böttcher RT and C Niehrs (2005) Fibroblast growth factor signaling during early vertebrate development. Endocr Rev 26, 63-77.
6. Braun S, U Aufdem Keller, H Steiling and S Werner. (2004). Fibroblast growth factors in epithelial repair and cytoprotection. Philos Trans R Soc Lond B Biol Sci 359:753-757.
7. Ziche M, S Donnini and L Morbidelli. (2004). Development of new drugs in angiogenesis. Curr Drug Targets 5:485-493.
8. Powers CJ, SW McLeskey and A Wellstein. (2000). Fibroblast growth factors, their receptors and signaling. Endocr Relat Cancer 7:165-197.
9. Wilson EL, DB Rifkin, F Kelly, MJ Hannocks and JL Gabrilove. (1991). Basic fibroblast growth factor stimulates myelopoiesis in long-term human bone marrow cultures. Blood 77:954-960.
10. Kashiwakura I and TA Takahashi. (2005). Fibroblast growth factor and ex vivo expansion of hematopoietic progenitor cells. Leuk Lymphoma 46:329-333.
11. Allouche M and A Bikfalvi. (1995). The role of fibroblast growth factor-2 (FGF-2) in hematopoiesis. Prog Growth Factor Res 6:35-48.
12. Dumont DJ, TP Yamaguchi, RA Conlon, J Rossant and ML Breitman. (1992). tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors. Oncogene 7:1471-1480.
13. Sato TN, Y Qin, CA Kozak and KL Audus. (1993). Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system. Proc Natl Acad Sci USA 90:9355-9358.
14. Arai F, A Hirao, M Ohmura, H Sato, S Matsuoka, K Takubo, K Ito, GY Koh and T Suda. (2004). Tie2=angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 118:149-161.
15. Arai F and T Suda. (2007). Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche. Ann N Y Acad Sci 1106:41-53.
16. Matsunaga S, M Okigaki, M Takeda, A Matsui, S Honsho, A Katsume, E Kishita, C Jishan, T Kurihara, Y Adachi, A Mansukhani, M Kobara, Y Matoba, T Tatsumi and H Matsubara. (2009). Endothelium-targeted overexpression of constitutively active FGF receptor induces cardioprotection in mice myocardial infarction. J Mol Cell Cardiol 46:663-673.
17. Adachi Y, S Taketani, H Oyaizu, K Ikebukuro, R Tokunaga and S Ikehara. (1999). Apoptosis of colorectal adenocarcinoma induced by 5-FU and=or IFN-gamma through caspase 3 and caspase 8. Int J Oncol 15:1191-1196.
18. Koike-Kiriyama N, Y Adachi, K Minamino, M Iwasaki, K Nakano, K Koike, H Yamada, H Mukaide, A Shigematsu, T Mizokami, M Matsumura and S Ikehara. (2007). Human cord blood cells can differentiate into retinal nerve cells. Acta Neurobiol Exp 67:359-365.
19. Sugihara A, Y Adachi, M Inaba, H Hisha, K Sugiura, S Miyashima, Y Amoh, S Taketani, H Oyaizu, K Ikebukuro, M Kawamura, H Genba, T Horio and S Ikehara. (1999). Age-dependent abnormalities of hematopoietic stem cells in (NZW x BXSB)F1 mice. Stem Cells 17:357-365.
20. Kushida T, M Inaba, H Hisha, N Ichioka, T Esumi, R Ogawa, H Iida and S Ikehara. (2001). Intra-bone marrow injection of allogeneic bone marrow cells: a powerful new strategy for treatment of intractable autoimmune diseases in MRL=lpr mice. Blood 97:3292-3299.
21. Dexter TM, E Spooncer, P Simmons and TD Allen. (1984). Long-term marrow culture: an overview of techniques and experience. Kroc Found Ser 18:57-96.
22. Okada S, H Nakauchi, K Nagayoshi, S Nishikawa, Y Miura and T Suda. (1992). In vivo and in vitro stem cell function of c-kit-and Sca-1-positive murine hematopoietic cells. Blood 80:3044-3050.
23. Yamamoto O, T Hamada, N Tokui and Y Sasaguri. (2001). Comparison of three in vitro assay systems used for assessing cytotoxic effect of heavy metals on cultured human keratinocytes. J UOEH 23:35-44.
24. Garcia RL, MD Coltrera and AM Gown. (1989). Analysis of proliferative grade using anti-PCNA=cyclin monoclonal antibodies in fixed, embedded tissues. Comparison with flow cytometric analysis. Am J Pathol 134:733-739.
25. van Engeland M, LJ Nieland, FC Ramaekers, B Schutte and CP Reutelingsperger. (1998). Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 31:1-9.
26. Ikehara S. (2003). New strategies for BMT, organ transplantation, and regeneration therapy. Hematology 8:77-81.
27. Ikebukuro K, Y Adachi, Y Suzuki, M Iwasaki, K Nakano, Y Koike,HMukaide, Y Yamada, S Fujimoto, Y Seino,HOyaizu, A Shigematsu, N Kiriyama, Y Hamada, Y Kamiyama and S Ikehara. (2006). Synergistic effects of injection of bone marrow cells into both portal vein and bone marrow on tolerance induction in transplantation of allogeneic pancreatic islets. Bone Marrow Transplant 38:657-664.
28. Suzuki Y, Y Adachi, K Minamino, Y Zhang, M Iwasaki, K Nakano, Y Koike and S Ikehara. (2005). A new strategy for treatment of malignant tumor: intra-bone marrow-bone marrow transplantation plus CD4-donor lymphocyte infusion. Stem Cells 23:365-370.
29. Frassoni F, F Gualandi, M Podestà, AM Raiola, A Ibatici, G Piaggio, M Sessarego, N Sessarego, M Gobbi, N Sacchi, M Labopin and A Bacigalupo. (2008). Direct intrabone transplant of unrelated cord-blood cells in acute leukaemia: a phase I=II study. Lancet Oncol 9:831-839.
30. Mauch P, JS Greenberger, L Botnick, E Hannon and S Hellman. (1980). Evidence for structured variation in selfrenewal capacity within long-term bone marrow cultures. Proc Natl Acad Sci USA 77:2927-2930.
31. Kiel MJ and SJ Morrison. (2008). Uncertainty in the niches that maintain haematopoietic stem cells. Nat Rev Immunol 8:290-301.
32. LaVallee TM, IA Prudovsky, GA McMahon, X Hu and T Maciag. (1998). Activation of the MAP kinase pathway by FGF-1 correlates with cell proliferation induction while activation of the Src pathway correlates with migration. J Cell Biol 141:1647-1658.
33. Lao DH, P Yusoff, S Chandramouli, RJ Philp, CW Fong, RA Jackson, TY Saw, CY Yu and GR Guy. (2007). Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation. J Biol Chem 282:9117-9126.
34. Allouche M and A Bikfalvi. (1995). The role of fibroblast growth factor-2 (FGF-2) in hematopoiesis. Prog Growth Factor Res 6:35-48.
35. Allouche M, F Bayard, S Clamens, G Fillola, P Sié and F Amalric. (1995). Expression of basic fibroblast growth factor (bFGF) and FGF-receptors in human leukemic cells. Leukemia 9:77-86.
36. Gabrilove JL, K White, Z Rahman and EL Wilson. (1994). Stem cell factor and basic fibroblast growth factor are synergistic in augmenting committed myeloid progenitor cell growth. Blood 83:907-910.
37. Chen QS, ZY Wang and ZC Han. (1999). Enhanced growth of megakaryocyte colonies in culture in the presence of heparin and fibroblast growth factor. Int J Hematol 70: 155-162.
38. Koritschoner NP, P Bartunek, S Knespel, G Blendinger and M Zenke. (1999). The fibroblast growth factor receptor FGFR-4 acts as a ligand dependent modulator of erythroid cell proliferation. Oncogene 18:5904-5914.