The effect of sulfur mustard and nitrogen mustard on corneal collagen degradation induced by the enzyme collagenase

Cutaneous and Ocular Toxicology

Volumn 29, Issue 4, 2010, Pages 234-240

  Naderi, Mostafa ^a   Jadidi, Khosro ^a   Falahati, Farzaneh ^b   Alavi, Saayyed Ali ^b  

^a BAQIYATALLAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Department of Biochemistry   (Iran)

Author keywords

Collagenase; Cornea; Nitrogen mustard; Sulfur mustard

Indexed keywords

CHLORMETHINE; COLLAGENASE; HYDROXYPROLINE; MUSTARD GAS; TOXIN;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ARTICLE; COLLAGEN DEGRADATION; CONTROLLED STUDY; CORNEA; DRUG EFFECT; INCUBATION TIME; NONHUMAN; PROTEIN CONTENT; SEDIMENT;

ALKYLATING AGENTS; ANIMALS; CATTLE; COLLAGEN; COLLAGENASES; CORNEA; DRUG THERAPY, COMBINATION; HYDROXYPROLINE; IRRITANTS; MECHLORETHAMINE; MUSTARD GAS;

EID: 78049361330     PISSN: 15569527     EISSN: 15569535     Source Type: Journal    
DOI: 10.3109/15569527.2010.491102     Document Type: Article

References (41)

1. Borak J, Sidell FR. Agents of chemical warfare: SM. Ann Emerg Med 1992; 21:303-308.
2. Smith KJ, Hurst CG, Moeller RB, Skelton HG, Sidell FR. SM: its continuing threat as a chemical warfare agent, the cutaneous lesions induced, progress in understanding its mechanism of action, its long-term health efects, and new developments for protection and therapy. J Am Acad Dermatol 1995; 32:765-776.
3. Watson AP, Grifn GD. Toxicity of vesicant agents scheduled for destruction by the chemical stockpile disposal program. Environ Health Perspect 1992; 98:259-280.
4. Papirmeister B, Gross CL, Meier HL, et al. Molecular basis for mustard-induced vesication. Fundam Appl Toxicol 1985; 5(suppl):S134-S149.
5. Gross CL, Meier HL, Papirmeister B, Brinkley FB, Johnson JB. SM lowers nicotinamide adenine dinucleotide concentrations in human skin grafted to athymic nude mice. Toxicol Appl Pharmacol 1985; 81:85-90.
6. Dacre JC, Goldman M. Toxicology and pharmacology of the chemical warfare agent SM. Pharmacol Rev 1996; 48:289-326.
7. Geeraets WJ, Abedi S, Blanke RV. Acute corneal injury by mustard gas. South Med J 1977; 70:348-350.
8. Dahl H, Gluud B, Vangsted P, Norn M. Eye lesions induced by mustard gas. Acta Ophthalmol Suppl 1985; 63: 30-31.
9. Mann I. Delayed mustard gas-keratitis: a study of eighty-four cases of delayed mustard gas keratitis ft-ted with contact lenses. Br J Ophthalmol 1944; 28: 441-447.
10. Farhoodi M. Intoxications and Burns Induced by Chemical Warfare Agents; Mashad, Iran: JDM Press. 1986.
11. Safarinejad MR, Moosavi SA, Montazeri B. Ocular injuries caused by mustard gas: diagnosis, treatment, and medical defense. Mil Med 2001; 166:67-70.
12. Hughes WF. Mustard gas injuries to the eyes. Arch Ophthalmol 1942; 27:582-589.
13. Etezad-Razavi M, Mahmoudi M, Hefazi M, Balali-Mood M. Delayed ocular complications of mustard gas poisoning and the relationship with respiratory and cutaneous complications. Clin Exp Ophthalmol 2006; 34: 342-346.
14. Benezra D, Foidart JM. Collagens and non collagen-ous proteins in the human eye. I. Corneal stroma in vivo and keratocyte production in vitro. Curr Eye Res 1981; 1: 101-110.
15. Fini ME, Girard MT, Matsubara M. Collagenolytic/gelatino-lytic enzymes in corneal wound healing. Acta Ophthalmol Suppl 1992; 202:26-33.
16. Birkedal-Hansen H. Catabolism and turnover of col-lagens: collagenases. Methods Enzymol 1987; 144: 140-171.
17. Fields GB, Van Wart HE, Birkedal-Hansen H. Sequence spe-cifcity of human skin fbroblast collagenase: evidence for the role of collagen structure in determining the collagenase cleavage site. J Biol Chem 1987; 262:6221.
18. Leung EW, Fife L, Smith RE, Kay E P. Extracellular matrix components in retrocorneal fbrous membrane in comparison to corneal endothelium and Descemet̀s membrame. Mol Vis 2000; 6:5-23.
19. Berman MB. Regulation of corneal fbbroblast MMP-1 collagenase secretion by plasmin. Cornea 1993; 12: 420-432.
20. Riley GP, Harrall RL, Watson PG, Cawston TE, Hazleman BL. Collagenase (MMP-1) and TIMP-1 in destructive corneal disease associated with rheumatoid arthritis. Eye 1995; 6:703-718.
21. Daniels JT, Limb GA, Saarialho-Kere U, Murphy G, Khaw PT. Human corneal epithelial cells require MMP-1 for HGF-mediated migration on collagen I. Invest Ophthalmol Vis Sci 2003; 44:1048-1055.
22. Bergmann M, Stein WH. A new principle for the determination of amino acids, and its application to collagen and gelatin. J Biol Chem 1939; 128:217-232.
23. Bradford MM. A rapid and sensitive method for the quan-titation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
24. Zor T, Selinger Z. Linearization of the Bradford protein assay increases its sensitivity: theoretical and experimental studies. Anal Biochem 1996; 236:302-308.
25. Jampol LM, Axelrod A, Tessler H. Pathways of the eyes response to topical nitrogen mustard. Invest Ophthalmol 1976; 15:486-489.
26. Banin E, Morad Y, Berenshtein E, Obolensky A, Yahalom C, Goldich J, et al. Injury induced by chemical warfare agents: characterization and treatment of ocular tissues exposed to nitrogen mustard. Invest Ophthalmol Vis Sci 2003; 44:2966-2972.
27. Pleyer U, Sherif Z, Baatz H, Hartmann C. Delayed mustard gas keratopathy: clinical fndings and confocal microscopy. Am J Ophthalmol 1999; 128:506-507.
28. Mann I, Pullinger BD. Te pathology of cholesterin and fat deposition in mustard gas injuries of the cornea. Br J Ophthalmol 1942; 26:503-507.
29. Mann I, Pullinger BD. A study of mustard gas lesion of the eyes for rabbits and men. Am J Ophthalmol 1944; 26: 1253-1277.
30. Waring GO, Bourne WM, Edelhauser HF, Kenyon KR. Te corneal endothelium: normal and pathologic structure and function. Ophthalmology 1982; 89: 531-590.
31. Doughman DJ, Van Horn D, Rodman WP, Byrnes P, Lindstrom RL. Human corneal endothelial layer repair during organ culture. Arch Ophthalmol 1976; 94: 1791-1796.
32. Van Horn DL, Hyndiuk RA. Endothelial wound repair in primate cornea. Exp Eye Res 1975; 21:113-124.
33. Ross WCJ. Biological Alkylating Agents. London, UK: Butterworths. 1962.
34. Wheeler GP. Studies related to the mechanisms of action of cytotoxic alkylating agents: a review. Cancer Res 1962; 22:651-688.
35. Byrne MP, Broomfeld CA, Stites WE. Mustard gas crosslink-ing of proteins through referential alkylation of cysteines. J Protein Chem 1996; 15:131-136.
36. Goodlad GA. Esterifcation of protein and amino acid car-boxyl groups by mustard gas and related compounds. Biochim Biophys Acta 1957; 24:645-646.
37. Moore S, Stein WH, Fruton JS. Chemical reactions of mustard gas and related compounds. II. Te reaction of mustard gas with carboxy groups and with the amino groups of amino acids and peptides. J Org Chem 1946; 11:675-680.
38. Herriott RM, Anson ML, Northrup JH. Reaction of enzymes and proteins with mustard gas. J Gen Physiol 1946; 30:185-210.
39. Davis SB, Ross W F. Te reaction of mustard gas with proteins. J Am Chem Soc 1947; 69:1177-1185.
40. Noort D, Verheij ER, Hulst AG, de Jong LP, Benschop HP. Characterization of SM induced structural modifca-tions in human hemoglobin by liquid chromatography-tandem mass spectrometry. Chem Res Toxicol 1996; 9: 781-787.
41. Dillman JF, McGary KL, Schlager JJ. SM induces the formation of keratin aggregates in human epidermal keratinocytes. Toxicol Appl Pharmacol 2003; 193:228-236.