BRAF drives synovial fibroblast transformation in rheumatoid arthritis

Journal of Biological Chemistry

Volumn 285, Issue 45, 2010, Pages 34299-34303

  Weisbart, Richard H ^a   Chan, Grace ^a   Heinze, Emil ^b   Mory, Rachel ^b   Nishimura, Robert N ^c   Colburn, Keith ^d,e  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^b OLIVE VIEW UCLA MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Jerry L Pettis Memorial VA Medical Center   (United States)

^e LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICULAR CARTILAGES; AUTOINHIBITORY DOMAIN; FIBROBLAST PROLIFERATION; FIRST-PASSAGE; KINASE DOMAINS; N-TERMINALS; RHEUMATOID ARTHRITIS; SPLICE VARIANTS; THERAPEUTIC INTERVENTION;

BONE; CARTILAGE; FIBROBLASTS; HEALTH; LIGAMENTS; RNA;

CELL CULTURE;

B RAF KINASE; SMALL INTERFERING RNA;

ADULT; AGED; ARTICLE; ARTICULAR CARTILAGE; CELL PROLIFERATION; CELL TRANSFORMATION; CLINICAL ARTICLE; CODON; CONTACT INHIBITION; CONTROLLED STUDY; CULTURE MEDIUM; DNA ISOLATION; DNA SEQUENCE; FEMALE; FIBROBLAST; GENE DELETION; GENE MUTATION; HUMAN; HUMAN CELL; MALE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN DOMAIN; RESTRICTION MAPPING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVIUM;

ADULT; AGED; AGED, 80 AND OVER; ARTHRITIS, RHEUMATOID; BONE AND BONES; CARTILAGE, ARTICULAR; CELL PROLIFERATION; FEMALE; FIBROBLASTS; HUMANS; MALE; MIDDLE AGED; MUTATION; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS B-RAF; RNA SPLICE SITES; RNA, SMALL INTERFERING; SYNOVIAL MEMBRANE;

EID: 78049356654     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C110.168195     Document Type: Article

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