Antioxidative effects of thiazide diuretics in refractory hypertensive patients: A randomized crossover trial of chlortalidone and trichlormethiazide

Arzneimittel-Forschung/Drug Research

Volumn 60, Issue 10, 2010, Pages 612-616

  Sato, Koichi ^a   Dohi, Yasuaki ^b   Kojima, Masayoshi ^b   Takase, Hiroyuki ^b   Suzuki, Shin ^a   Ito, Shigenori ^a  

^a East Medical Center Higashi Municipal Hospital City of Nagoya   (Japan)

^b NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

24 h ambulatory blood pressure monitoring; Chlortalidone; Oxidative stress; Refractory hypertension; Thiazide diuretics; Trichlormethiazide

Indexed keywords

8 ISOPROSTANE; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CAS 133 67 5; CAS 137682 53 4; CAS 21829 25 4; CAS 77 36 1; CHLORTALIDONE; LOW DENSITY LIPOPROTEIN; MALONALDEHYDE; NIFEDIPINE; TRICHLORMETHIAZIDE; UNCLASSIFIED DRUG; VALSARTAN;

ADD ON THERAPY; AMBULATORY MONITORING; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD LEVEL; BLOOD PRESSURE; BLOOD PRESSURE REGULATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; HYPERTENSION; INFLAMMATION; MALE; OXIDATIVE STRESS; RANDOMIZED CONTROLLED TRIAL;

EID: 78049341738     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296334     Document Type: Article

References (25)

1. The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA. 2002;288:2981-97.
2. Wright JT Jr, Dunn JK, Cutler JA, Davis BR, Cushman WC, Ford CE, et al., the ALLHAT Coolaborative Research Group. Outcomes in hypertensive black and nonblack patirnts treated with chlortalidone, amlodipine, and lisinopril. JAMA. 2005;293:1595-608.
3. Psaty BM, Lumley T, Furberg CD, Schellenbaum G, Pahor M, Alderman MH, et al. Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis. JAMA. 2003;289:2534-44.
4. Hypertension Detection and Follow-up Program Cooperative Group. Five-year findings of the Hypertension Detection and Follow-up Program I. Reduction in mortality of persons with high blood pressure, including mild hypertension. JAMA. 1979;242:2562-71.
5. The Multiple Risk Factor Intervention Trial Research Group (MRFIT). Mortality rates after 10.5 years for hypertensive participants in the Multiple Risk Factor Intervension Trial. Circulation. 1990;82:1616-28.
6. SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA. 1991;265:3255-64.
7. Neaton JD, Girmm RH Jr, Prineas RJ, Stamler J, Granditis GA, Elmer PJ, et al., the Treatment of Mild Hypertension study. Final results. Treatment of Mild Hypertension Study Research Group. JAMA. 1993:270:713-24.
8. Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. The Seventh report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7). JAMA. 2003;289:2560-72.
9. Skalska A, Gasowski J, Stepniewski M, Grodzicki T. Antioxidative protection in hypertensive patients treated with diuretics. Am J Hypertens. 2005;18:1130-2.
10. Redon J, Oliva MR, Tormos C, Giner V, Chaves J, Iradi A, et al. Antioxidant activities and oxidative stress byproducts in human hypertension. Hypertension. 2003;41:1096-101. (Pubitemid 36548609)
11. de Champlain J, Wu R, Girouard H, Karas M, El Midaoui A, Laplante MA, et al. Oxidative stress in hypertension. Clin Exp Hypertens. 2004;26:593-601.
12. Sato K, Dohi Y, Kojima M, Miyagawa K, Takase H, Katada E, et al. Effects of ascorbic acid on ambulatory blood pressure in elderly patients with refractory hypertension. Arzneimittelforschung. 2006;56:535-40. (Pubitemid 44196683)
13. Miyagawa K, Ohashi M, Yamashita S, Kojima M, Sato K, Ueda R, et al. Increased oxidative stress impairs endothelial modulation of contractions in arteries from sponteously hypertensive rats. J Hypertens. 2007;25:415-21.
14. Uehara Y, Kawabata Y, Shirahase H, Wada K, Hashizume Y, Morishita S, et al. Oxygen radical scavengers and renal protection by indapamide diuretic in salt-induced hypertension of Dahl strain rats. J Cardiovasc Pharmacol. 1993;22(Suppl 6):S42-6.
15. DellOmo G, Penno G, Prato SD, Pedrinelli R. Chlortalidone improves endothelial-mediated vascular responses in hypertension complicated by nondiabetic metabolic syndrome. J Cardiovasc Pharmacol Ther. 2005:10:265-72. (Pubitemid 43003336)
16. Cooperative Study in Elderly Hypertensives Study. Randomized double-blind comparison of a calcium antagonist and a diuretic in elderly hypertensives. Hypertension 1999;34:1129-33.
17. Rifai N, Tracy R, Ridker PM. Clinical efficacy of an automated high-sensitivity C-reactive protein assay. Clin Chem. 1999:45:2136-41.
18. Kitano S, Kanno T, MaekawaM, Sakurabashi I, Kotani K, Hisatomi H, et al. Improvedmethod for the immunological detection of malondialdehyde-modified low-density lipoproteins in human serum. Anal Chim Acta. 2004;509:229-35. (Pubitemid 38340721)
19. Walsh SW, Vaugham JE, Wang Y, Roberts LJ II. Placental isoprostane is significantly increased in preeclampsia. FASEB J. 2000;14:1289-96. (Pubitemid 30439737)
20. Boegehold MA. Flow-dependent arteriolar dilation in normotensive rats fed low or high-salt diets. Am J Physiol Heart Circ Physiol. 1995;269:H1407-14.
21. Fujita T, Ito Y. Salt loads attenuate potassium-induced vasodilation of forearmvasculature in humans. Hypertension. 1993;21:772-8. (Pubitemid 23171639)
22. Zhou MS, Schulman IH, Jaimes EA, Raij L. Thiazide diuretics endothelial function, and vascular oxidative stress. J Hypertens. 2008:26:494-500.
23. Dohi Y, Ohashi M, Sugiyama M, Takase H, Sato K, Ueda R. Candesartan reduces oxidative stress and inflammation in patients with essential hypertension. Hypertens Res. 2003;26:691-7.
24. Portaluppi F, Boari B, Manfredini R. Oxidative stress in essential hypertension. Curr Pharm Des. 2004;10:1695-8.
25. Japanese Society of Hypertension. The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009). Hypertens Res. 2009;32:3-107.