Can D-dimer testing help emergency department physicians to detect acute aortic dissections?;D-dimer testi akut aort disseksiyonlarını belirlemede acil servis hekimlerine yardımcı olabilir mi?

Anadolu Kardiyoloji Dergisi

Volumn 10, Issue 5, 2010, Pages 434-439

  Ersel, Murat ^a   Aksay, Ersin ^a   Kiyan, Selahattin ^a   Bayraktaroǧlu, Selen ^a   Yürüktümen, Aslihan ^a   Özsaraç, Murat ^a   Çalkavur, Tanzer ^a  

^a EGE UNIVERSITY   (Turkey)

Author keywords

Acute aortic dissection; D dimer; Diagnostic value of tests; Emergency department; Fibrin degradation products

Indexed keywords

D DIMER;

ACUTE DISEASE; ADULT; AGED; AORTA DISSECTION; ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; EMERGENCY WARD; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL PRACTICE; MEDICAL RECORD REVIEW; PATIENT ASSESSMENT; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; TURBIDIMETRY;

EID: 78049336990     PISSN: 13028723     EISSN: None     Source Type: Journal    
DOI: 10.5152/akd.2010.142     Document Type: Article

References (31)

1. Mehta RH, Suzuki T, Hagan PG, Bossone E, Gilon D, Llovet A, et al. Predicting death in patients with acute type a aortic dissection. Circulation 2002; 105: 200-6.
2. Hagan PG, Nienaber CA, Isselbacher EM, Bruckman D, Karavite DJ, Russman PL, et al. The International Registry of Acute Aortic Dissection (IRAD): New insights into an old disease. JAMA 2000; 283: 897-903.
3. Sarasin FP, Louis-Simonet M, Gaspoz JM, Junod AF. Detecting acute thoracic aortic dissection in the emergency department: time constraints and choice of the optimal diagnostic test. Ann Emerg Med 1996; 28: 278-88.
4. Sie P. The value of laboratory tests in the diagnosis of venous thromboembolism. Haematologica 1995; 80: 57-60.
5. The DVTENOX Study Group. Markers of haemostatic system activation in acute deep venous thrombosis evolution during the first days of heparin treatment. Thromb Haemost 1993; 70: 909-14.
6. Weber T, Högler S, Auer J, Berent R, Lassnig E, Kvas E, et al. D-dimer in acute aortic dissection. Chest 2003; 123: 1375-8.
7. Eggebrecht H, Naber CK, Bruch C, Kröger K, Von Birgelen C, Schmermund A, et al. Value of plasma fibrin D-dimers for detection of acute aortic dissection. J Am Coll Cardiol 2004; 44: 804-9.
8. Perez A, Abbet P, Drescher MJ. D-dimers in the emergency department evaluation of aortic dissection. Acad Emerg Med 2004; 11: 397-400.
9. Hazui H, Fukumoto H, Negoro N, Hoshiga M, Muraoka H, Nishimoto M, et al. Simple and useful tests for discriminating between acute aortic dissection of the ascending aorta and acute myocardial infarction in the emergency setting. Circ J 2005; 69: 677-82.
10. Akutsu K, Sato N, Yamamoto T, Morita N, Takagi H, Fujita N, et al. A rapid bedside D-dimer assay (Cardiac D-dimer) for screening of clinically suspected acute aortic dissection. Circ J 2005; 69: 397-403.
11. Ohlmann P, Faure A, Morel O, Petit H, Kabbaj H, Meyer N, et al. Diagnostic and prognostic value of circulating D-Dimers in patients with acute aortic dissection. Crit Care Med 2006; 34: 1358-64.
12. Weber T, Rammer M, Auer J, Maurer E, Aspoeck G, Eber B. Plasma concentrations of D-dimer predict mortality in acute type A aortic dissection. Heart 2006; 92: 836-7.
13. Hazui H, Nishimoto M, Hoshiga M, Negoro N, Muraoka H, Murai M, et al. Young adult patients with short dissection length and thrombosed false lumen without ulcer-like projections are liable to have false-negative results of D-dimer testing for acute aortic dissection based on a study of 113 cases. Circ J 2006; 70: 1598-601.
14. Spinner T, Spes C, Mudra H. Elevated D-dimer at acute chest pain: Pulmonary embolism or aortic dissection? Intensivmedizin und Notfallmedizin 2006; 43: 570-4.
15. Sbarouni E, Georgiadou P, Marathias A, Geroulanos S, Kremastinos DT. D-dimer and BNP levels in acute aortic dissection. Int J Cardiol 2007; 122: 170-2.
16. Wiegand J, Koller M, Bingisser R. Does a negative D-dimer test rule out aortic dissection? Swiss Med Wkly 2007; 137: 462.
17. Sodeck G, Domanovits H, Schillinger M, Ehrlich MP, Endler G, Herkner H, et al. D-dimer in ruling out acute aortic dissection: a systematic review and prospective cohort study. Eur Heart J 2007; 28: 3067-75.
18. Paparella D, Malvindi PG, Scrascia G, De Ceglia D, Rotunno C, Tunzi F, et al. D-dimers are not always elevated in patients with acute aortic dissection. J Cardiovasc Med (Hagerstown) 2009; 10: 212-4.
19. Suzuki T, Distante A, Zizza A, Trimarchi S, Villani M, Salerno Uriarte JA, et al. Diagnosis of acute aortic dissection by D-dimer: the International Registry of Acute Aortic Dissection Substudy on Biomarkers (IRAD-Bio) experience. Circulation 2009; 119: 2702-7.
20. Knaut AL, Cleveland JC Jr. Aortic emergencies. Emerg Med Clin North Am 2003; 21: 817-45.
21. Erbel R, Alfonso F, Boileau C, Dirsch O, Eber B, Haverich A, et al. Task Force on Aortic Dissection, European Society of Cardiology. Diagnosis and management of aortic dissection. Eur Heart J 2001; 22: 1642-81.
22. Suzuki T, Katoh H, Watanabe M, Kurabayashi M, Hiramori K, Hori S, et al. Novel biochemical diagnostic method for aortic dissection. Results of a prospective study using an immunoassay of smooth muscle myosin heavy chain. Circulation 1996; 93: 1244-9.
23. Khan IA, Nair CK. Clinical, diagnostic, and management perspectives of aortic dissection. Chest 2002; 122: 311-28.
24. Woo Y, Bavaria J, Mohler M. Clinical features and diagnosis of thoracic aortic aneurysm. [CDROM] In: Rose BD, ed. UpToDate. Wellesley, MA: UpToDate; 2004. 2 CDROMs.
25. Marill KA. Serum D-dimer is a sensitive test for the detection of acute aortic dissection: a pooled meta-analysis. J Emerg Med 2008; 34: 367-76.
26. Von Kodolitsch Y, Schwartz AG, Nienaber CA. Clinical prediction of acute aortic dissection. Arch Intern Med 2000; 160: 2977-82.
27. Shinohara T, Suzuki K, Okada M, Shiigai M, Shimizu M, Maehara T, et al. Soluble elastin fragments in serum are elevated in acute aortic dissection. Arterioscler Thromb Vasc Biol 2003; 23: 1839-44.
28. Suzuki T, Katoh H, Tsuchio Y, Hasegawa A, Kurabayashi M, Ohira A, et al. Diagnostic implications of elevated levels of smooth-muscle myosin heavy-chain protein in acute aortic dissection. Ann Intern Med 2000; 133: 537-41.
29. Rapaport SI, Rao LV. The tissue factor pathway: How it has become a prima ballerina. Thromb Haemost 1995; 74: 7-17.
30. Salvagno GL, Targher G, Franchini M, Lippi G. Plasma D-dimer in the diagnosis of acute aortic dissection. Eur Heart J 2008; 29: 1207.
31. Mir MA. Aortic dissection in pursuit of a serum marker. Am J Emerg Med 2008; 26: 942-5.