Risk of sudden death in asymptomatic brugada syndrome: Not as high as we thought and not as low as we wished ... but the contrary

Journal of the American College of Cardiology

Volumn 56, Issue 19, 2010, Pages 1585-1588

  Viskin, Sami ^a   Rosso, Raphael ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Brugada syndrome; exercise testing; ST segment elevation

Indexed keywords

AJMALINE; FLECAINIDE;

BRUGADA SYNDROME; DEFIBRILLATOR; ELECTROCARDIOGRAPHY; EXERCISE TEST; HEART ARREST; HEART ARRHYTHMIA; HEART ELECTROPHYSIOLOGY; HEART VENTRICLE FIBRILLATION; HUMAN; NOTE; PRIORITY JOURNAL; RISK ASSESSMENT; ST SEGMENT ELEVATION; SUDDEN DEATH;

EID: 78049326581     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2010.07.019     Document Type: Editorial

References (35)

1. M. Paul, J. Gerss, and E. Schulze-Bahr Role of programmed ventricular stimulation in patients with Brugada syndrome: a meta-analysis of worldwide published data Eur Heart J 28 2007 2126 2133
2. I. Goldenberg, A.J. Moss, and D.R. Peterson Risk factors for aborted cardiac arrest and sudden cardiac death in children with the congenital long-QT syndrome Circulation 117 2008 2184 2191
3. S. Viskin, and O. Rogowski Asymptomatic Brugada syndrome: a cardiac ticking time-bomb? Europace 9 2007 707 710
4. F. Sacher, V. Probst, and Y. Iesaka Outcome after implantation of a cardioverter-defibrillator in patients with Brugada syndrome: a multicenter study Circulation 114 2006 2317 2324
5. R. Rosso, A. Glick, and M. Glikson Outcome after implantation of cardioverter defibrillator in patients with Brugada syndrome: a multicenter Israeli study (ISRABRU) Isr Med Assoc J 10 2008 435 439
6. P. Brugada, R. Brugada, L. Mont, M. Rivero, P. Geelen, and J. Brugada Natural history of Brugada syndrome: the prognostic value of programmed electrical stimulation of the heart J Cardiovasc Electrophysiol 14 2003 455 457
7. S.G. Priori, C. Napolitano, and M. Gasparini Natural history of Brugada syndrome: insights for risk stratification and management Circulation 105 2002 1342 1347 (Pubitemid 34260426)
8. L. Eckardt, V. Probst, and J.P. Smits Long-term prognosis of individuals with right precordial ST-segment-elevation Brugada syndrome Circulation 111 2005 257 263
9. A.K. Gehi, T.D. Duong, L.D. Metz, J.A. Gomes, and D. Mehta Risk stratification of individuals with the Brugada electrocardiogram: a meta-analysis J Cardiovasc Electrophysiol 17 2006 577 583
10. V. Probst, C. Veltmann, and L. Eckardt Long-term prognosis of patients diagnosed with Brugada syndrome: results from the FINGER Brugada syndrome registry Circulation 121 2010 635 643
11. S. Kamakura, T. Ohe, and K. Nakazawa Long-term prognosis of probands with Brugada-pattern ST-segment elevation in leads V1-V3 Circ Arrhythm Electrophysiol 2 2009 495 503
12. B. Benito, A. Sarkozy, and L. Mont Gender differences in clinical manifestations of Brugada syndrome J Am Coll Cardiol 52 2008 1567 1573
13. F. Sacher, P. Meregalli, and C. Veltmann Are women with severely symptomatic Brugada syndrome different from men? J Cardiovasc Electrophysiol 19 2008 1181 1185
14. S. Viskin Brugada syndrome in children: don't ask, don't tell? Circulation 115 2007 1970 1972
15. S. Richter, A. Sarkozy, and C. Veltmann Variability of the diagnostic ECG pattern in an ICD patient population with Brugada syndrome J Cardiovasc Electrophysiol 20 2009 69 75
16. W. Shimizu, K. Matsuo, and M. Takagi Body surface distribution and response to drugs of ST segment elevation in Brugada syndrome: clinical implication of eighty-seven-lead body surface potential mapping and its application to twelve-lead electrocardiograms J Cardiovasc Electrophysiol 11 2000 396 404
17. T. Ikeda, A. Abe, and S. Yusu The full stomach test as a novel diagnostic technique for identifying patients at risk of Brugada syndrome J Cardiovasc Electrophysiol 17 2006 602 607
18. K. Shimeno, M. Takagi, K. Maeda, H. Tatsumi, A. Doi, and M. Yoshiyama Usefulness of multichannel Holter ECG recording in the third intercostal space for detecting type 1 Brugada ECG: comparison with repeated 12-lead ECGs J Cardiovasc Electrophysiol 20 2009 1026 1031
19. D.I. Keller, H. Huang, and J. Zhao A novel SCN5A mutation, F1344S, identified in a patient with Brugada syndrome and fever-induced ventricular fibrillation Cardiovasc Res 70 2006 521 529
20. A. Sarkozy, G.B. Chierchia, and G. Paparella Inferior and lateral electrocardiographic repolarization abnormalities in Brugada syndrome Circ Arrhythm Electrophysiol 2 2009 154 161
21. M.J. Junttila, P. Brugada, and K. Hong Differences in 12-lead electrocardiogram between symptomatic and asymptomatic Brugada syndrome patients J Cardiovasc Electrophysiol 19 2008 380 383
22. H. Morita, K.F. Kusano, and D. Miura Fragmented QRS as a marker of conduction abnormality and a predictor of prognosis of Brugada syndrome Circulation 118 2008 1697 1704
23. A. Grimster, O.R. Segal, and E.R. Behr Type I Brugada electrocardiogram pattern during the recovery phase of exercise testing Europace 10 2008 897 898
24. M.E. Guevara-Valdivia, P. Iturralde Torres, A. de Micheli, L. Colin Lizalde, A. Medeiros Domingo, and J.A. Gonzalez-Hermosillo [Electrocardiographic changes during stress test in a patient with "Brugada syndrome"] Arch Cardiol Mex 71 2001 66 72
25. M. Papadakis, E. Petzer, and S. Sharma Unmasking of the Brugada phenotype during exercise testing and its association with ventricular arrhythmia on the recovery phase Heart 95 2009 2022
26. A.S. Amin, E.A. de Groot, J.M. Ruijter, A.A. Wilde, and H.L. Tan Exercise-induced ECG changes in Brugada syndrome Circ Arrhythm Electrophysiol 2 2009 531 539
27. H. Makimoto, E. Nakagawa, and H. Takaki Augmented ST-segment elevation during recovery from exercise predicts cardiac events in patients with Brugada syndrome J Am Coll Cardiol 56 2010 1576 1584
28. T. Miyazaki, H. Mitamura, S. Miyoshi, K. Soejima, Y. Aizawa, and S. Ogawa Autonomic and antiarrhythmic drug modulation of ST-segment elevation in patients with Brugada syndrome J Am Coll Cardiol 27 1996 1061 1070
29. M. Yokokawa, H. Okamura, and T. Noda Neurally mediated syncope as a cause of syncope in patients with Brugada electrocardiogram J Cardiovasc Electrophysiol 21 2010 186 192
30. Empiric Quinidine for Asymptomatic Brugada Syndrome http://www. brugadasyndrome.info/ Accessed September 22, 2010
31. S. Viskin, A.A. Wilde, H.L. Tan, C. Antzelevitch, W. Shimizu, and B. Belhassen Empiric quinidine therapy for asymptomatic Brugada syndrome: time for a prospective registry Heart Rhythm 6 2009 401 404
32. N.A. Estes III, and R.L. Page To the editorresponse: irreplaceable antiarrhythmic medications are disappearing: the case of quinidine Heart Rhythm 7 2010 863 864
33. G. Olsson To the editormarket withdrawal of quinidine bisulfate (kinidin durules) in 2006 Heart Rhythm 7 2010 864
34. S. Viskin, B. Belhassen, and A.A. Wilde To the editorirreplaceable antiarrhythmic medications are disappearing: the case of quinidine Heart Rhythm 7 2010 863
35. P.E. Vardas, and E.M. Kanoupakis To the editorold drugs never die; they just fade away Heart Rhythm 7 2010 864