Hypertrophy, gene expression, and beating of neonatal cardiac myocytes are affected by microdomain heterogeneity in 3D

Biomedical Microdevices

Volumn 12, Issue 6, 2010, Pages 1073-1085

  Curtis, Matthew W ^a   Sharma, Sadhana ^b   Desai, Tejal A ^c   Russell, Brenda ^b  

^a University of Illinois at Chicago   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Beat frequency; Cardiomyocyte; Cell remodeling; Focal adhesion; Hypertrophy; Mechanotransduction; Microenvironment; Microstructure; Spontaneous contraction; Three dimensions

Indexed keywords

BEAT FREQUENCY; CARDIOMYOCYTES; FOCAL ADHESIONS; HYPERTROPHY; MECHANOTRANSDUCTION; MICROENVIRONMENTS; SPONTANEOUS CONTRACTION; THREE DIMENSIONS;

ADHESION; CELL CULTURE; GENE EXPRESSION; HEART; MICROSTRUCTURE; PATHOLOGY; PEDIATRICS; THREE DIMENSIONAL; TISSUE ENGINEERING;

ANIMAL CELL CULTURE;

ALPHA ACTININ; ANKYRIN; BETA 1 ADRENERGIC RECEPTOR; BETA 2 MICROGLOBULIN; CYTOCHROME C OXIDASE; ETHYLENE GLYCOL DIMETHACRYLATE; PHENYLEPHRINE; POLYMER; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DENSITY; CELL PROLIFERATION; CELL SIZE; CELL STRUCTURE; CONTROLLED STUDY; GENE EXPRESSION; HEART BEAT; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HYPERTROPHY; IMAGE RECONSTRUCTION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MYOFIBROBLAST; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SARCOMERE; THREE DIMENSIONAL IMAGING; TISSUE ENGINEERING; TOPOGRAPHY;

ANIMALS; ANIMALS, NEWBORN; CARDIOMEGALY; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; FIBROBLASTS; GENE EXPRESSION PROFILING; MUSCLE CONTRACTION; MYOCYTES, CARDIAC; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY;

CYPRINIDAE; RATTUS;

EID: 78049290317     PISSN: 13872176     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10544-010-9461-y     Document Type: Article

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