The welcome resurgence of the α-cell: A pro glucagon commentary

Diabetes

Volumn 59, Issue 11, 2010, Pages 2735-2736

  Robertson, R Paul ^a  

^a PACIFIC NORTHWEST RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; GHRELIN; GLUCAGON; GLUTAMIC ACID; PROGLUCAGON; SOMATOSTATIN; ZINC;

AUTONOMIC NERVOUS SYSTEM; GLUCAGON RELEASE; GLUCOSE TRANSPORT; GLYCEMIC CONTROL; GLYCOGENOLYSIS; HUMAN; HYPOGLYCEMIA; INSULIN RELEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NOTE; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

GLUCAGON; GLUCAGON-SECRETING CELLS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ZINC;

EID: 78049287284     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-1238     Document Type: Note

References (6)

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2. Zhou H, Tran PO, Yang S, Zhang T, LeRoy E, Oseid E, Robertson RP. Regulation of alpha cell function by the beta cell during hypoglycemia in Wistar rats: the "switch-off" hypothesis. Diabetes 2004;53:1482-1487
3. Gromada J, Franklin I, Wollheim CB. Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains. Endocrine Reviews 2007;28:84-116
4. Cooperberg BA, Cryer PE. Insulin reciprocally regulates glucagon secretion in humans. Diabetes 2010;59:2936-2940
5. Zhou H, Zhang T, Harmon JS, Bryan J, Robertson RP. Zinc, not insulin, regulates the rat alpha-cell response to hypoglycemia in vivo. Diabetes 2007;56:1107-1112
6. Slucca M, Harmon JS, Oseid EA, Bryan J, Robertson RP. ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation. Diabetes, 2010;59:128-134