Dynamic object representations in infants with and without fragile X syndrome

Frontiers in Human Neuroscience

Volumn 4, Issue , 2010, Pages

  Farzin, Faraz ^a   Rivera, Susan M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Attention; Dorsal ventral visual streams; Motion; Object tracking; Occlusion

Indexed keywords

ARTICLE; ATTENTION; BRAIN DEVELOPMENT; BRAIN REGION; CHILD; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; EVOKED VISUAL RESPONSE; EYE TRACKING; FEMALE; FRAGILE X SYNDROME; HUMAN; INFANT; MALE; NERVE CELL NETWORK; PRESCHOOL CHILD; TASK PERFORMANCE; VISION; VISUAL STIMULATION; VISUAL SYSTEM FUNCTION;

EID: 78049254019     PISSN: 16625161     EISSN: 16625161     Source Type: Journal    
DOI: 10.3389/neuro.09.012.2010     Document Type: Article

References (51)

1. Atkinson, J. (1993). A neurobiological approach to the development of "where" and "what" systems for spatial representation in human infants. In Spatial Representation: Problems in Philosophy and Psychology, N. Eilan, R. McCarthy and B. Brewer, eds (Oxford, UK, Blackwell), pp. 325-339.
2. Atkinson, J. (2000). The Developing Visual Brain. Oxford, Oxford University Press.
3. Awh, E., and Jonides, J. (1999). Overlapping mechanisms of attention and spatial working memory. Trends Cogn. Sci. (Regul. Ed.) 10, 433-437.
4. Baillargeon, R. (1993). The object concept revisited: new directions in the investigation of infants' physical knowledge. In Visual Perception and Cognition in Infancy, C. E. Granrud, ed. (London, Lawrence Erlbaum Associates), pp. 265-315.
5. Battelli, L., Cavanagh, P., Intriligator, J., Tramo, M. J., Henaff, M. A., Michel, F., and Barton, J. J. (2001). Unilateral right parietal damage leads to bilateral defi cit for high-level motion. Neuron 32, 985-995.
6. Battelli, L., Pascual-Leone, A., and Cavanagh, P. (2007). The 'when' pathway of the right parietal lobe. Trends Cogn. Sci. (Regul. Ed.) 11, 204-210.
7. Beckett, L., Qilu, Y., and Long, A. N. (2005). The Impact of Fragile X: Prevalence, Numbers Affected, and Economic Impact. A white paper prepared for the National Fragile X Foundation. Davis, CA, University of California.
8. Brown, W. T., Jenkins, E. C., Friedman, E., Brooks, J., Wisniewski, K., Raguthu, S., and French, J. (1982). Autism is associated with the fragile-X syndrome. J. Autism Dev. Disord. 12, 303-308.
9. Cavanagh, P. (1992). Attention-based motion perception. Science 257, 1563-1565.
10. Comery, T. A., Harris, J. B., Willems, P. J., Oostra, B. A., Irwin, S. A., Weiler, I. J., and Greenough, W. T. (1997). Abnormal dendritic spines in fragile X knockout mice: maturation and pruning defi cits. Proc. Natl. Acad. Sci. U.S.A. 94, 5401-5404.
11. Cornish, K. M., Munir, F., and Cross, G. (1999). Spatial cognition in males with Fragile-X syndrome: evidence for a neuropsychological phenotype. Cortex 35, 263-271.
12. Crawford, D., Acuna, J. M., and Sherman, S. L. (2001). FMR1 and the fragile X syndrome: human genome epidemiology review. Genet. Med. 3, 359-371.
13. Culham, J. C., Brandt, S. A., Cavanagh, P., Kanwisher, N. G., Dale, A. M., and Tootell, B. (1998). Cortical fMRI activation produced by attentive tracking of moving targets. J. Neurophysiol. 80, 2657-2670.
14. Culham, J. C., Cavanagh, P., and Kanwisher, N. G. (2001). Attention response functions: Characterizing brain areas using fMRI activation during parametric variations of attentional load. Neuron 32, 737-745.
15. Farzin, F., Whitney, D., Hagerman, R. J., and Rivera, S. M. (2008). Contrast detection in infants with fragile X syndrome. Vision Research, 48, 1471-1478.
16. Irwin, S. A., Galvez, R., Weiler, I. J., Beckel- Mitchener, A., and Greenough, W. T. (2002). Brain structure and functions of fMR1 protein. In Fragile X Syndrome: Diagnosis, Treatment and Research, 3rd Edn, R. J. Hagerman and P. J. Hagerman, eds (Baltimore, The Johns Hopkins University Press), pp. 191-205.
17. Johnson, M. H., Mareschal, D., and Csibra, G. (2001). The functional development and integration of the dorsal and ventral visual pathways: a neurocomputational approach. In The Handbook of Developmental Cognitive Neuroscience, C. A. Nelson and M. Luciana eds (Cambridge, MA, MIT Press), pp. 339-351.
18. Johnston, A., McOwan, P. W., and Buxton, H. (1992). A computational model of the analysis of some first-order and second-order motion patterns by simple and complex cells. Proc. R. Soc. Lond. B. 250, 297-306.
19. Kaldy, Z., and Leslie, A., M. (2003). Identifi cation of objects in 9 month old infants: integrating what and where information. Dev. Sci. 6, 360-373.
20. Kogan, C. S., Boutet, I., Cornish, K., Zangenehpour, S., Mullen, K. T., Holden, J. J., Der Kaloustian, V. M., Andermann, E., and Chaudhuri, A. (2004a). Differential impact of the fMR1 gene on visual processing in fragile X syndrome. Brain 127(Pt. 3), 591-601.
21. Kogan, C. S., Bertone, A., Cornish, K., Boutet, I., Der Kaloustian, V. M., Andermann, E., Faubert, J., and Chaudhuri, A. (2004b). Integrative cortical dysfunction and pervasive motion perception defi cit in fragile X syndrome. Neurology 63, 1634-1639.
22. Leslie, A. M., and Kaldy, Z. (2001). Indexing individual objects in infant working memory. J. Exp. Child. Psychol. 78, 61-74
23. Leslie, A. M., Xu, F., Tremoulet, P. D., and Scholl, B. J. (1998). Indexing and the object concept: developing 'what' and 'where' systems. Trends Cogn. Sci. (Regul. Ed.) 2, 10-18.
24. Mareschal, D., and Johnson, M. H. (2003). The "what" and "where" of object representations in infancy. Cognition 88, 259-276a.
25. McDowell, J. E., Dyckman, K. A., Austin, B. P., and Clementz, B. A. (2008). Neurophysiology and neuroanatomy of reflexive and volitional saccades: evidence from studies of humans. Brain Cogn. 68, 255-270.
26. Milner, A. D., and Goodale, M. A. (1995). The Visual Brain in Action. Oxford, Oxford University Press.
27. Mohr, H. M., and Linden, D. E. J. (2005). Separation of the systems for color and spatial manipulation in working memory revealed by a dual-task procedure. J. Cogn. Neurosci. 17, 355-366.
28. Mullen, E. M. (1995). Mullen Scales of Early Learning. Circle Pines, MN, American Guidance Service Inc.
29. Nishida, S., and Sato, T. (1995). Motion aftereffect with fl ickering test patterns reveal higher stages of motion processing. Vision Res. 35, 477-490.
30. Olson, I. R., Gatenby, J. C., Leung, H. C., Skudlarski, P., and Gore, J. C. (2003). Neuronal representation of occluded objects in the human brain. Neuropsychologia 42, 95-104.
31. Pasternak, T., and Greenlee, M. (2005). Working memory in primate visual systems. Nat. Rev. Neurosci. 6, 97-107.
32. Rao, S. C., Rainer, G., and Miller, E. K. (1997). Integration of what and where in the primate prefontal cortex. Science 276, 821-824.
33. Reddy, K. S. (2005). Cytogenetic abnormalities and fragile-X syndrome in Autism Spectrum Disorder. BMC Med. Genet. 6, 3.
34. Richardson, D. C., and Kirkham, N. Z. (2004). Multimodal events and moving locations: Eye movements of 6-month-olds reveal dynamic spatial indexing. J. Exp. Psychol. Gen. 133, 46-62.
35. Rivera, S. M., Menon, V., White, C. D., Glaser, B., and Reiss, A. L. (2002). Functional brain activation during arithmetic processing in females with fragile X Syndrome is related to FMR1 protein expression. Hum. Brain Mapp. 16, 206-18.
36. Rossetti, Y., and Pisella, L. (2002). Several "vision for action" systems: A guide to dissociating and integrating dorsal and ventral functions. In Attention and Performance XIX: Common mechanisms in Perception and Action. W. Prinz and B. Hommel, eds (Oxford, England, Oxford University Press). pp. 62-119.
37. Scerif, G., Cornish, K., Wilding, J., Driver, J., and Karmiloff-Smith, A. (2004). Visual search in typically developing toddlers and toddlers with Fragile X or Williams syndrome. Dev. Sci. 7, 116-130.
38. Scerif, G., Karmiloff-Smith, A., Campos, R., Elsabbagh, M., Driver, J., and Cornish, K. (2005). To look or not to look? Typical and atypical development of oculomotor control. J. Cogn. Neurosci. 17, 591-604.
39. Scholl, B. J., Pylyshyn, Z. W., and Feldman, J. (2001). What is a visual object? Evidence from target merging in multiple object tracking. Cognition 80, 159-177.
40. Seiffert, A. E., and Cavanagh, P. (1998). Position displacement, not velocity, is the cue to motion detection of second-order stimuli. Vision Res. 38, 3569-3582.
41. Shuwairi, S. M., Curtis, C. E., and Johnson, S. P. (2007). Neural substrates of dynamic object occlusion. J. Cogn. Neurosci. 19, 1275-1285.
42. Spelke, S. E., Katz, G., Purcell, S. E., Ehrlich, S. M., and Breilinger, K. (1994). Early knowledge of object motion: continuity and inertia. Cognition 51, 131-176.
43. Sperling, G. (1989). Three stages and two systems of visual processing. Spat. Vis. 4, 183-207.
44. Todd, J. J., and Marois, R. (2004). Capacity limit of visual short-term memory in human posterior parietal cortex. Nature 428, 751-754.
45. Tremoulet, P. D., Leslie, A. M., and Hall, D. G. (2000). Infant individuation and identifi cation of objects. Cogn. Dev. 15, 499-522.
46. Ungerleider, L. G., and Mishkin, M. (1982). Two cortical visual systems. In Analysis of Visual Behavior, D. J. Ingle, M. A. Goodale and R. J. W. Mansfield, eds (Cambridge, MIT Press). pp. 549-586.
47. Verkerk, A. J., Pieretti, M., Sutcliffe, J. S., Fu, Y. H., Kuhl, D. P., Pizzuti, A., Reiner, O., Richards, S., Victoria, M. F., Zhang, F. P., Eussen, B.E., van Ommen, G.-J. B., Blonden, L. A. J., Riggins, G. J., Chastain, J. L., Kunst, C. B., Galjaard, H., Caskey, C. T., Nelson, D. L., Oostra, B.A., and Warren, S. T. (1991). Identifi cation of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell 65, 905-914.
48. Wilcox, T. (1999). Object individuation: infants' use of shape, size, pattern, and color. Cognition 72, 125-166.
49. Wilcox, T., and Schweinle, A. (2002). Object individuation and event mapping: developmental changes in infants' use of featural information. Dev. Sci. 5, 132-150.
50. Xu, Y., and Chun, M. M. (2006). Dissociable neural mechanisms supporting visual short-term memory for objects. Nature 440, 91-95.
51. Yantis, S. (1992). Multi-element visual tracking: attention and perceptual organization. Cogn. Psychol. 24, 295-340.