Overcoming bottlenecks in drug discovery

Drug Discovery World

Volumn 11, Issue 4, 2010, Pages 29-33

  Perrior, Trevor ^a  

^a Domainex Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NEW DRUG;

ARTICLE; AUTOMATION; BACULOVIRUS EXPRESSION SYSTEM; DRUG APPROVAL; DRUG COST; DRUG RESEARCH; HIGH THROUGHPUT SCREENING; PROCESS OPTIMIZATION; PROTEIN PROTEIN INTERACTION; REIMBURSEMENT;

EID: 78049235594     PISSN: 14694344     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Adams, CP, Brantner, VV. Spending on new drug development Health Economics 2010 19:130-141 http://onlinelibrary.wiley.com/doi/10.1002/hec.1454/ abstract
2. Keyhani, S, Diener-West, M, Powe, N. Trends in Drug Development Time and Price. Academy Health. Meeting (2005: Boston, Mass.). Abstr AcademyHealth Meet. 2005; 22: abstract no. 3676 http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f= 103623139.html.
3. Colas, P. High-throughput screening assays to discover small-molecule inhibitors of protein interactions Current Drug Discovery Technologies 2008 5:190-199.
4. Kool, J, Lingeman, H, Niessen, W, Irth, H. High throughput screening methodologies classified for major drug target classes according to target signalling pathways. Combinatorial Chemistry and High Throughput Screening 2010 13:548-561.
5. Zhu, Z and Cuozzo, J. High-throughput affinity-based technologies for small-molecule drug discovery. Journal of Biomolecular Screening 2009 1157-1164.
6. Makela, A and Oker-Blom, C. The Baculovirus Display Technology - an evolving instrument for molecular screening and drug delivery. Combinatorial Chemistry and High Throughput Screening 2008 11:86-98. (Pubitemid 351347213)