Past and current tendency for facial flushing after a small dose of alcohol is a marker for increased risk of upper aerodigestive tract cancer in Japanese drinkers

Cancer Science

Volumn 101, Issue 11, 2010, Pages 2497-2498

  Yokoyama, Akira ^a   Yokoyama, Tetsuji ^b   Omori, Tai ^c  

^a KURIHAMA NATIONAL HOSPITAL   (Japan)

^b NATIONAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^c KAWASAKI MUNICIPAL HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ALDEHYDE DEHYDROGENASE ISOENZYME 2;

ALCOHOL CONSUMPTION; CANCER RISK; CONTROLLED STUDY; ESOPHAGUS CANCER; FLUSHING; FOLLOW UP; HEAD AND NECK CANCER; HUMAN; JAPANESE; LETTER; MALE; PRIORITY JOURNAL; SCREENING TEST; SENSITIVITY AND SPECIFICITY; SQUAMOUS CELL CARCINOMA; STRUCTURED QUESTIONNAIRE; WORLD HEALTH ORGANIZATION;

ALCOHOL DRINKING; ALDEHYDE DEHYDROGENASE; ASIAN CONTINENTAL ANCESTRY GROUP; ESOPHAGEAL NEOPLASMS; FLUSHING; GENETIC PREDISPOSITION TO DISEASE; HUMANS; JAPAN; LARYNGEAL NEOPLASMS; MALE; MOUTH NEOPLASMS; PHARYNGEAL NEOPLASMS; POLYMORPHISM, GENETIC; QUESTIONNAIRES; RISK FACTORS;

EID: 77958592146     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2010.01709.x     Document Type: Letter

References (10)

1. Oze I, Matsuo K, Hosono S et al. Comparison between self-reported facial flushing after alcohol consumption and ALDH2 Glu504Lys polymorphisms for risk of upper aerodigestive tract cancer in a Japanese population. Cancer Sci 2010; 101: 1875-80.
2. Secretan B, Straif K, Baan R et al. A review of human carcinogens-Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish. Lancet Oncol 2009; 10: 1033-4.
3. Brooks PJ, Enoch MA, Doldman D, Li TK, Yokoyama A. The alcohol flushing response: an unrecognized risk factor of esophageal cancer from alcohol consumption. PLoS Med 2009; 6: e50.
4. Higuchi S, Muramatsu T, Shigemori K et al. The relationship between low Km aldehyde dehydrogenase phenotype and drinking behavior in Japanese. J Stud Alcohol 1992; 53: 170-5.
5. Ishiguro S, Sasazuki S, Inoue M et al. Effect of alcohol consumption, cigarette smoking and flushing response on esophageal cancer risk: a population-based cohort study (JPHC study). Cancer Lett 2009; 275: 240-6.
6. Yokoyama T, Yokoyama A, Kato H et al. Alcohol flushing, alcohol and aldehyde dehydrogenase genotypes, and risk for esophageal squamous cell carcinoma in Japanese men. Cancer Epidemiol Biomarkers Prev 2003; 12: 1227-33.
7. Asakage T, Yokoyama A, Haneda T et al. Genetic polymorphisms of alcohol and aldehyde dehydrogenases and drinking, smoking, and diet in Japanese men with oral and pharyngeal squamous cell carcinoma. Carcinogenesis 2007; 28: 865-74.
8. Yokoyama A, Yokoyama T, Muramatsu T et al. Macrocytosis, a new predictor for esophageal squamous cell carcinoma in Japanese men. Carcinogenesis 2003; 24: 1773-8.
9. Yokoyama A, Omori T, Yokoyama T et al. Risk of squamous cell carcinoma of the upper aerodigestive tract in cancer-free alcoholic Japanese men: an endoscopic follow-up study. Cancer Epidemiol Biomarkers Prev 2006; 15: 2209-15.
10. Yokoyama T, Yokoyama A, Kumagai Y et al. Health risk appraisal models for mass screening of esophageal cancer in japanese men. Cancer Epidemiol Biomarkers Prev 2008; 17: 2846-54.