Phase solubility studies of the inclusion complexes of repaglinide with β-cyclodextrin and β-cyclodextrin derivatives

Farmacia

Volumn 58, Issue 5, 2010, Pages 620-628

  Nicolescu, Camelia ^a   Aramǎ, Corina ^a   Nedelcu, Angela ^a   Monciu, Crina Maria ^a  

^a CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

cyclodextrin; Hydroxypropyl cyclodextrin; Inclusion complexes; Phase solubility diagrams; Randomly methylated cyclodextrin; Repaglinide

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; BETA CYCLODEXTRIN; BETA CYCLODEXTRIN DERIVATIVE; PHOSPHATE; RANDOMLY METHYLATED BETA CYCLODEXTRIN; REPAGLINIDE; UNCLASSIFIED DRUG; WATER;

ARTICLE; DRUG DETERMINATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; LIPOPHILICITY;

EID: 77958579211     PISSN: 00148237     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Aleem O., Kuchekar B., Pore Y., Late S., Effect of β- cyclodextrin and hydroxypropyl-β- cyclodextrin complexation on physicochemical properties and antimicrobial activity of cefdinir, J.Pharm.Biomed. Anal, 47, 535-540, (2008).
2. Araujo D., Tsuneda S., Cereda C., Carvalho., Prete P. et. al., Development and pharmacological evaluation of ropivacaine-2- hydroxypropyl - β-cyclodextrin inclusion complex, Eur. J. Pharm. Sci., 33, 60-71, (2008).
3. Brewster M.E., Loftsson T., Cyclodextrins as pharmaceutical solubilizers, Adv.Drug Deliv.Rev., 59, 645-666, (2007).
4. Brewster M.E., Vandecruys, R., Peeters J., Neeskens P., Verreck G., Loftsson T., Comparative interaction of 2- hydroxypropyl - β-cyclodextrin and sulfobutylether-β- cyclodextrin with itraconazole: Phase-solubility behavior and stabilization of supersaturated drug solutions, Eur. J. Pharm. Sci., 34, 94-103, (2008).
5. Hassan H.A., Al-Marzouqi A.H., Jobe B., Hamza A., Ramadan G.A., Enhancement of dissolution amount and in vivo bioavailability of itraconazole by complexation with β- cyclodextrin using supercritical carbon dioxide, J.Pharm.Biomed. Anal, 45, 243-250, (2007).
6. Higuchi T., Connors K.A., Phase-solubility techniques, Adv.Anal.Chem.Instr., 4, 117-122, (1965).
7. Mandic Z., Gabelica V., Ionization, lipophilicity and solubility properties of repaglinide, J.Pharm.Biomed. Anal, 41, 866-871 (2006)
8. Munoz-Botella S., Martin M., Lerner D.A., Analytical applications of retinoid-cyclodextrin inclusion complexes, J.Pharm.Biomed. Anal, 14, 909-915 (1996)
9. Nicolescu C., Aramǎ C., Monciu C.M., Preparation and characterization of inclusion complexes between repaglinide and β-cyclodextrin, 2-hydroxypropyl- β-cyclodextrin and randomly methylated β-cyclodextrin, Farmacia, 58, 1, 78-88 (2010)
10. th Edition, Merck&Co., Inc.,Whitehouse Station, NJ, USA, (2006).
11. Ozkan Y., Atay T., Dikmen N., Işimer A., Aboul-Enein H.Y., Improvement of water solubility and in vitro dissolution rate of gliclazide by complexation with β -cyclodextrin, Pharm. Acta Helv., 74, 365-370, (2000).
12. Schalley, C., Analytical Methods in Supramolecular Chemistry, Wiley-VCH Verlag GmbH, Weinheim, 817-854 (2007)
13. Trandafirescu C., Gyeresi A., Aigner Z., Kata M., Epure C., Szabadai Z., Study of influence of citric acid on albendazole complexation with random methylated β - cyclodextrin, Farmacia, LVI, 1, 24-29 (2008)
14. Vica L., Bota S., Moisa C., Ganea M., Evaluation study of the inclusion complex of captopril - β - cyclodextrin, Farmacia, LV, 1, 93-97 (2007)