Urinary collagen fragments are significantly altered in diabetes: A link to pathophysiology

PLoS ONE

Volumn 5, Issue 9, 2010, Pages

  Maahs, David M ^a   Siwy, Justyna ^b   Argilés, Àngel ^c   Cerna, Marie ^d   Delles, Christian ^e   Dominiczak, Anna F ^e   Gayrard, Nathalie ^c   Iphöfer, Alexander ^f   Jänsch, Lothar ^f   Jerums, George ^g   Medek, Karel ^d   Mischak, Harald ^b,e   Navis, Gerjan J ^h   Roob, Johannes M ⁱ   Rossing, Kasper ^j   Rossing, Peter ^j   Rychlík, Ivan ^d   Schiffer, Eric ^b   Schmieder, Roland E ^k   Wascher, Thomas C ⁱ   Winklhofer Roob, Brigitte M ^l   Zimmerli, Lukas U ^e   Zürbig, Petra ^b   Snell Bergeon, Janet K ^a   more..

^a UNIVERSITY OF COLORADO DENVER   (United States)

^b MOSAIQUES DIAGNOSTICS GMBH   (Germany)

^c RD Nephrologie   (France)

^d CHARLES UNIVERSITY   (Czech Republic)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

^f HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^g UNIVERSITY OF MELBOURNE   (Australia)

^h UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

ⁱ MEDICAL UNIVERSITY OF GRAZ   (Austria)

^j STENO DIABETES CENTER   (Denmark)

^k UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^l UNIVERSITY OF GRAZ   (Austria)

more..

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; INSULIN; ORAL ANTIDIABETIC AGENT; PROTEOME;

ADULT; AMINO ACID SEQUENCE; ARTICLE; CAPILLARY ELECTROPHORESIS; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION REGULATION; HUMAN; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOPHYSIOLOGY; PROTEIN METABOLISM; PROTEOMICS; SEQUENCE ANALYSIS; URINE LEVEL; VALIDATION PROCESS;

ADULT; BIOLOGICAL MARKERS; COHORT STUDIES; COLLAGEN; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; EXTRACELLULAR MATRIX; FEMALE; HUMANS; MALE; MASS SPECTROMETRY; MIDDLE AGED; PROTEOMICS;

EID: 77958524202     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013051     Document Type: Article

References (56)

1. Thongboonkerd V (2007) Practical Points in Urinary Proteomics. J Proteome Res 6: 3881-3890.
2. Kolch W, Neususs C, Pelzing M, Mischak H (2005) Capillary electrophoresismass spectrometry as a powerful tool in clinical diagnosis and biomarker discovery. Mass Spectrom Rev 24: 959-977.
3. von Zur Muhlen C, Schiffer E, Zuerbig P, Kellmann M, Brasse M, et al. (2009) Evaluation of Urine Proteome Pattern Analysis for Its Potential To Reflect Coronary Artery Atherosclerosis in Symptomatic Patients. J Proteome Res 8: 335-345.
4. Decramer S, Wittke S, Mischak H, Zürbig P, Walden M, et al. (2006) Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis. Nat Med 12: 398-400.
5. Weissinger EM, Schiffer E, Hertenstein B, Ferrara JL, Holler E, et al. (2007) Proteomic patterns predict acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Blood 109: 5511-5519.
6. Mischak H, Kaiser T, Walden M, Hillmann M, Wittke S, et al. (2004) Proteomic analysis for the assessment of diabetic renal damage in humans. Clin Sci (Lond) 107: 485-495.
7. Meier M, Kaiser T, Herrmann A, Knueppel S, Hillmann M, et al. (2005) Identification of urinary protein pattern in type 1 diabetic adolescents with early diabetic nephropathy by a novel combined proteome analysis. J Diabetes Complications 19: 223-232.
8. Zimmerli LU, Schiffer E, Zürbig P, Kellmann M, Mouls L, et al. (2008) Urinary proteomics biomarkers in coronary artery disease. Mol Cell Proteomics 7: 290-298.
9. Rossing K, Mischak H, Rossing P, Schanstra JP, Wiseman A, et al. (2008) The urinary proteome in diabetes and diabetes-associated complications: new ways to assess disease progression and evaluate therapy. Proteomics Clin Appl 2: 997-1007.
10. Rossing K, Mischak H, Dakna M, Zürbig P, Novak J, et al. (2008) Urinary Proteomics in Diabetes and CKD. J Am Soc Nephrol 19: 1283-1290.
11. Snell-Bergeon JK, Maahs DM, Ogden LG, Kinney GL, Hokanson JE, et al. (2009) Evaluation of urinary biomarkers for coronary artery disease, diabetes, and diabetic kidney disease. Diabetes Technol Ther 11: 1-9.
12. Hull RL, Westermark GT, Westermark P, Kahn SE (2004) Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes. J Clin Endocrinol Metab 89: 3629-3643.
13. Marzban L, Park K, Verchere CB (2003) Islet amyloid polypeptide and type 2 diabetes. Exp Gerontol 38: 347-351.
14. Catania JM, Chen G, Parrish AR (2007) Role of matrix metalloproteinases in renal pathophysiologies. Am J Physiol Renal Physiol 292: F905-F911.
15. Kitsiou PV, Tzinia AK, Stetler-Stevenson WG, Michael AF, Fan WW, et al. (2003) Glucose-induced changes in integrins and matrix-related functions in cultured human glomerular epithelial cells. Am J Physiol Renal Physiol 284: F671-F679.
16. Tsilibary EC (2003) Microvascular basement membranes in diabetes mellitus. J Pathol 200: 537-546.
17. Mischak H, Coon JJ, Novak J, Weissinger EM, Schanstra JP, et al. (2009) Capillary electrophoresis-mass spectrometry as a powerful tool in biomarker discovery and clinical diagnosis: An update of recent developments. Mass Spectrom Rev 28: 703-724.
18. Dominiczak AF, Herget-Rosenthal S, Delles C, Fliser D, Fournier I, et al. (2010) Systems biology to battle vascular disease. Nephrol Dial Transplant 25: 1019-1022.
19. Molina F, Dehmer M, Perco P, Graber A, Girolami M, et al. (2010) Systems biology: opening new avenues in clinical research. Nephrol Dial Transplant 25: 1015-1018.
20. Ahmed N (2005) Advanced glycation endproducts-role in pathology of diabetic complications. Diabetes Res Clin Pract 67: 3-21.
21. Verzijl N, Degroot J, Thorpe SR, Bank RA, Shaw JN, et al. (2000) Effect of collagen turnover on the accumulation of advanced glycation end products. J Biol Chem 275: 39027-39031.
22. Rossing K, Mischak H, Dakna M, Zürbig P, Novak J, et al. (2008) Urinary Proteomics in Diabetes and CKD. J Am Soc Nephrol 19: 1283-1290.
23. Gettins PG (2002) Serpin structure, mechanism, and function. Chem Rev 102: 4751-4804.
24. Sandler M, Gemperli BM, Hanekom C, Kuhn SH (1988) Serum alpha 1- protease inhibitor in diabetes mellitus: reduced concentration and impaired activity. Diabetes Res Clin Pract 5: 249-255.
25. Hashemi M, Naderi M, Rashidi H, Ghavami S (2007) Impaired activity of serum alpha-1-antitrypsin in diabetes mellitus. Diabetes Res Clin Pract 75: 246-248.
26. Sandstrom CS, Ohlsson B, Melander O, Westin U, Mahadeva R, et al. (2008) An association between Type 2 diabetes and alpha-antitrypsin deficiency. Diabet Med 25: 1370-1373.
27. Sharma K, Lee S, Han S, Lee S, Francos B, et al. (2005) Two-dimensional fluorescence difference gel electrophoresis analysis of the urine proteome in human diabetic nephropathy. Proteomics 5: 2648-2655.
28. Grant PJ (2007) Diabetes mellitus as a prothrombotic condition. J Intern Med 262: 157-172.
29. Cahill MA (2007) Progesterone receptor membrane component 1: an integrative review. J Steroid Biochem Mol Biol 105: 16-36.
30. Gras F, Brunmair B, Quarre L, Szocs Z, Waldhausl W, et al. (2007) Progesterone impairs cell respiration and suppresses a compensatory increase in glucose transport in isolated rat skeletal muscle: a non-genomic mechanism contributing to metabolic adaptation to late pregnancy? Diabetologia 50: 2544-2552.
31. Lapolla A, Seraglia R, Molin L, Williams K, Cosma C, et al. (2009) Low molecular weight proteins in urines from healthy subjects as well as diabetic, nephropathic and diabetic-nephropathic patients: a MALDI study. J Mass Spectrom 44: 419-425.
32. Holmquist P, Torffvit O, Jorgensen PE, Torring N, Nexo E, et al. (2001) Early urinary changes in Tamm-Horsfall protein and epidermal growth factor in diabetic children. Pediatr Nephrol 16: 488-492.
33. Holmquist P, Torffvit O (2008) Tubular function in diabetic children assessed by Tamm-Horsfall protein and glutathione S-transferase. Pediatr Nephrol 23: 1079-1083.
34. Zhang R, Barker L, Pinchev D, Marshall J, Rasamoelisolo M, et al. (2004) Mining biomarkers in human sera using proteomic tools. Proteomics 4: 244-256.
35. Costacou T, Ferrell RE, Orchard TJ (2008) Haptoglobin genotype: a determinant of cardiovascular complication risk in type 1 diabetes. Diabetes 57: 1702-1706.
36. Costacou T, Ferrell RE, Ellis D, Orchard TJ (2009) Haptoglobin genotype and renal function decline in type 1 diabetes. Diabetes 58: 2904-2909.
37. Good DM, Wirtala M, McAlister GC, Coon JJ (2007) Performance characteristics of electron transfer dissociation mass spectrometry. Mol Cell Proteomics 6: 1942-1951.
38. Good DM, Coon JJ (2006) Advancing proteomics with ion/ion chemistry. Biotechniques 40: 783-789.
39. Gebauer P, Beckers JL, Bocek P (2002) Theory of system zones in capillary zone electrophoresis. Electrophoresis 23: 1779-1785.
40. Theodorescu D, Wittke S, Ross MM, Walden M, Conaway M, et al. (2006) Discovery and validation of new protein biomarkers for urothelial cancer: a prospective analysis. Lancet Oncol 7: 230-240.
41. Li J, Wang C, Kelly JF, Harrison DJ, Thibault P (2000) Rapid and sensitive separation of trace level protein digests using microfabricated devices coupled to a quadrupole-time-of-flight mass spectrometer. Electrophoresis 21: 198-210.
42. Li J, LeRiche T, Tremblay TL, Wang C, Bonneil E, et al. (2002) Application of microfluidic devices to proteomics research: identification of trace-level protein digests and affinity capture of target peptides. Mol Cell Proteomics 1: 157-168.
43. Rossing K, Mischak H, Dakna M, Zürbig P, Novak J, et al. (2008) Urinary Proteomics in Diabetes and CKD. J Am Soc Nephrol 19: 1283-1290.
44. American Diabetes Association (2008) Diagnosis and classification of diabetes mellitus. Diabetes Care 31 Suppl 1: S55-S60.
45. Finley JW, Burrell JB, Reeves PG (2007) Pinto bean consumption changes SCFA profiles in fecal fermentations, bacterial populations of the lower bowel, and lipid profiles in blood of humans. J Nutr 137: 2391-2398.
46. Zürbig P, Decramer S, Dakna M, Jantos J, Good DM, et al. (2009) The human urinary proteome reveals high similarity between kidney aging and chronic kidney disease. Proteomics 9: 2108-2117.
47. Good DM, Zurbig P, Argiles A, Bauer HW, Behrens G, et al. (2010) Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease. Mol Cell Proteomics Epub ahead of print.
48. Neuhoff N, Kaiser T, Wittke S, Krebs R, Pitt A, et al. (2004) Mass spectrometry for the detection of differentially expressed proteins: a comparison of surfaceenhanced laser desorption/ionization and capillary electrophoresis/mass spectrometry. Rapid Communications in Mass Spectrometry 18: 149-156.
49. Theodorescu D, Schiffer E, Bauer HW, Douwes F, Eichhorn F, et al. (2008) Discovery and validation of urinary biomarkers for prostate cancer. Proteomics Clin Appl 2: 556-570.
50. Jantos-Siwy J, Schiffer E, Brand K, Schumann G, Rossing K, et al. (2009) Quantitative Urinary Proteome Analysis for Biomarker Evaluation in Chronic Kidney Disease. J Proteome Res 8: 268-281.
51. Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc B (Methodological) 57: 125-133.
52. Kruskal WH, Wallis WA (1952) Use of ranks in one-criterion variance analysis. JASA 47: 583-621.
53. DeLeo JM (1993) Receiver operating characteristic laboratory (ROCLAB): Software for developing decision strategies that account for uncertainty. pp 318-325.
54. Zürbig P, Renfrow MB, Schiffer E, Novak J, Walden M, et al. (2006) Biomarker discovery by CE-MS enables sequence analysis via MS/MS with platformindependent separation. Electrophoresis 27: 2111-2125.
55. Coon JJ, Shabanowitz J, Hunt DF, Syka JE (2005) Electron transfer dissociation of peptide anions. J Am Soc Mass Spectrom 16: 880-882.
56. Syka JE, Coon JJ, Schroeder MJ, Shabanowitz J, Hunt DF (2004) Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry. Proc Natl Acad Sci U S A 101: 9528-9533.