Metabolism, transformation and distribution of Coptis chinensis total alkaloids in rat

Zhongguo Zhongyao Zazhi

Volumn 35, Issue 15, 2010, Pages 2017-2020

  Wang, Liang ^a   Ye, Xiaoli ^a   Li, Xuegang ^a   Chen, Zhu ^a   Chen, Xiaodan ^b   Gao, Ying ^a   Zhao, Zhongqi ^a   Huang, Wenwen ^a   Chen, Xin ^a   Yi, Jun ^a  

^a SOUTHWEST UNIVERSITY   (China)

^b Department of polytechnic engineering   (China)

Author keywords

Coptis chinensis total alkaloids; Distribution; Pharmacokinetics; Reversed phase hplc; Transformation

Indexed keywords

ALKALOID; COPTISINE; HERBERINE; JATRORRHIZINE; PALMATINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; COPTIS CHINENSIS; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG TISSUE LEVEL; DRUG TRANSFORMATION; FEEDING; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TRACT; LIVER; LUNG; MAXIMUM PLASMA CONCENTRATION; MEDICINAL PLANT; NONHUMAN; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STOMACH;

ALKALOIDS; ANIMALS; BIOTRANSFORMATION; COPTIS; DRUGS, CHINESE HERBAL; FEMALE; MALE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

EID: 77958518514     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: 10.4268/cjcmm20101523     Document Type: Article

References (13)

1. Nicholson J K, Wilson I D. Understanding 'global' systems biology. etabonomics and the continuum of metabolism [J]. Nat Rev Drug Discov, 2003,2(8):668.