Evaluation of the topical application of opioid analgesia for a leg ulcer of a sickle cell disease patient;Avaliação da analgesia de opioide tópico em úlcera de perna de paciente falcêmico

Revista Brasileira de Hematologia e Hemoterapia

Volumn 32, Issue 2, 2010, Pages 123-125

  Neves, Alexandre F ^a   Martins, Amanda ^b   Queiroz, Ana Maria M ^c   Thomé, Eleonora D'Avila ^d   Queiroz, Ana Paula A ^e   Lobo, Clarisse L C ^c  

^a Farmácia Hospitalar ^*  (Brazil)

^b Enfermeira   (Brazil)

^c Hematologista   (Brazil)

^d Dermatologista   (Brazil)

^e Chefe do Serviço de Farmácia   (Brazil)

Author keywords

Analgesics; Hemoglobin sc disease; Pain

Indexed keywords

EID: 77958511709     PISSN: 15168484     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1516-84842010005000033     Document Type: Article

References (21)

1. WHO. Advisory Group on Hereditary Disease. Geneve: WHO, 1985.
2. Schechter AN, Noguchi CT. Sickle hemoglobin polymer: structurefunction correlates. In: Embury SH, Hebbel RP, Mohandas N et al. (eds.). Sickle Cell Disease: basic principles and clinical practice. New York: Lippincott-Raven, 1994. p. 33-51.
3. Fadlon E, Vordermeier S, Person TC. Blood polymorphonuclear leukocytes from the majority of sickle cells patients in the crisis phase of the disease show enhanced adhesion to vascular endothelium and increased expression of CD64. Blood. 1998;91(1):266-274.
4. Hebbel RP, Vercellotti GM. The endothelial biology of sickle cell disease. J Lab Clin Med. 1997;129(3):288-293.
5. Hebbel RP, Moldow CF, Steinberg MH. Modulation of erythrocyteendotelial interactions and the vasocclusive severity of sickling disorders. Blood. 1981;58(5):947-952.
6. Wang CW. The patophisiology, prevention, and treatment of stroke in sickle cell disease. Curr Opin Hematol. 2007;14(3):191-197.
7. Platt OS, Thorington BD, Brambilla DJ. Pain in sickle cell disease. Rates and risk factors. N Engl J Med. 1991;325(1):11-16.
8. Serjeant GR, Ceulaer CD, Lethbridge R. The painful crisis of homozygous sickle cell disease: clinical features. Br J Haematol. 1994;87(3):586-591.
9. Koshy M, Entsuah R, Koranda A. Leg ulcers in patients with sickle cell disease. Blood. 1989;74(4):1403-1408.
10. Ademiluyi SA, Rotimi VO, Cocker AO. The anaerobic and aerobic bacterial flora of leg ulcers in patients with sickle-cell disease. J Infect. 1988;17(2):115-120.
11. Flock P, Gibbs L, Sykes N. Diamorphine-metronidazole gel effective for treatment of painful infected leg ulcers. J Pain Symptom Manage. 2000;20(6):396-397.
12. Krajnik M, Zylicz Z, Finlay I, Luczak J, van Sorge AA. Potencial uses of topical opioids in palliative care - report of 6 cases. Pain. 1999;80(1-2):121-125.
13. Twillman RK, Long TD, Cathers TA, Mueller DW. Treatment of painful skin ulcers with topical opioids. J Pain Symptom Manage. 1999;17(4):288-292.
14. Ballas SK. Treatment of painful sickle cell leg ulcers with topical opioids. Blood. 2002;99(3):1096.
15. Zeppetella G, Paul J, Ribeiro MD. Analgesic efficacy of morphine applied topically to painful ulcers. J Pain Symptom Manage. 2003; 25(6):555-558.
16. Zeppetella G, Ribeiro MD. Morphine in intrasite gel applied topically to painful ulcers. J Pain Symptom Manage. 2005;29(2):118-119.
17. Abdelmageed R, Labyad N, Watson DG, Pournamdari M, Cable CG, Stanley E. Evaluation of the stability of morphine sulphate in combination with Instillagel. J Clin Pharm Ther. 2008;33(3):263-271.
18. Levine JD, Taiwo YO. Involvement of the mu-opiate receptor in peripheral analgesia. Neuroscience. 1989;32:571-575.
19. Samczewska G, Kolodziejska J, Cialkowska-Rysz A, Piechota- Urbanska M. The effect of cross-linking base on the properties of hydrogels with carbopol and on pharmaceutical availability of morphine sulphate. Arch Med Sci. 2007;3(1):19-26.
20. Nahata MC, Morosco RS, Hipple TF. Stability of morphine sulfate in bacteriostatic 0.9% sodium chloride injection stored in glass vials at two temperatures. Am J Hosp Pharm. 1992;49(11):2785-2786.
21. Lobo CLC, Marra VN, Silva RMG. Crises dolorosas na doença falciforme. Rev. Bras. Hematol. Hemoter. 2007;29(3):247-258.