Potential uses of topical opioids in palliative care - Report of 6 cases

Pain

Volumn 80, Issue 1-2, 1999, Pages 121-125

  Krajnik, Mal̃gorzata ^a   Zylicz, Zbigniew ^b   Finlay, Ilora ^c   Łuczak, Jacek ^d   Van Sorge, Adriaan A ^e  

^a NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^b Hospice Rozenheuvel   (Netherlands)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^e RIJNSTATE HOSPITAL   (Netherlands)

Author keywords

Cutaneous pain; Palliative care; Topical opioids

Indexed keywords

AMITRIPTYLINE; ANTIBIOTIC AGENT; CARBAMAZEPINE; DIAMORPHINE; FENTANYL; MORPHINE; MORPHINE SULFATE; OPIATE; OPIATE RECEPTOR; PARACETAMOL; SULFADIAZINE SILVER; TROMETAMOL;

ADULT; AGED; ANALGESIA; ARTICLE; CANCER PAIN; CLINICAL ARTICLE; CONSTIPATION; DRUG EFFICACY; DRUG USE; FEMALE; HUMAN; INTRAARTICULAR DRUG ADMINISTRATION; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; NAUSEA; ORAL DRUG ADMINISTRATION; PAIN; PALLIATIVE THERAPY; PRIORITY JOURNAL; SKIN CANCER; SKIN ULCER; TOPICAL DRUG ADMINISTRATION; WOUND;

ADMINISTRATION, TOPICAL; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; FEMALE; GELS; HUMANS; MALE; MIDDLE AGED; MORPHINE; NEOPLASMS; PAIN, INTRACTABLE; PALLIATIVE CARE;

EID: 0033061510     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(98)00211-5     Document Type: Article

References (39)

1. Antonijevic, I., Mousa, S.A., Schäfer, M. and Stein, C., Perineurial defect and peripheral opioid analgesia in inflammation, J. Neurosci., 15 (1995) 165-172.
2. Back, I.N. and Finlay, I., Analgesic effect of topical opioids on painful skin ulcers, J. Pain. Symptom Manage., 10 (1995) 493.
3. Basbaum, A.I. and Levine, J.D., Opiate analgesia. How central is a peripheral target?, N. Engl. J. Med., 325 (1991) 1168-1169.
4. Boerner, U., Abbott, S. and Roe, R.L., The metabolism of morphine and heroin in man, Drug Metab. Rev., 41 (1975) 39-73.
5. Cabot, P.J., Dodd, P.R., Cramond, T. and Smith, M.T., Characterization of non-conventional opioid binding sites in rat and human lung, Eur. J. Pharmacol., 268 (1994) 247-255.
6. Cabot, P.J., Cramond, T. and Smith, M.T., Quantitative autoradiography of peripheral opioid binding sites in rat lung, Eur. J. Pharmacol., 310 (1996) 47-53.
7. Dickenson, A.H., Where and how do opioids act? In: G.F. Gebhart, D.L. Hammond and T.S. Jensen (Eds.), Proceedings of the 7th World Congress on Pain. Progress in Pain Research and Management, Vol. 2, IASP Press, Seattle, WA, 1994, pp. 525-549.
8. Dickenson, A.H., Pharmacology of pain transmission and control, Pain, 1996. An Updated Review Refresher Course Syllabus (8th World Congress on Pain), IASP Press, Seattle, WA, 1996, pp. 113-121.
9. Duckett, J.W., Cangiano, T., Cubina, M., Howe, C. and Cohen, D., Intravesical morphine analgesia after bladder surgery, J. Urol., 157 (1997) 1407-1409.
10. Eisenberg, E., Vos, B.P. and Strassman, A.M., The peripheral antinociceptive effect of morphine in a rat model of facial pain, Neurosci., 72 (1996) 519-525.
11. Feldberg, W. and Paton, W.D.M., Release of histamine from skin and muscle in the cat by opium alkaloids and other histamine liberators, J. Physiol. (London), 114 (1951) 490-509.
12. Hassan, A.H.S., Ableitner, A., Stein, C. and Herz, A., Inflammation of the rat paw enhances axonal transport of opioid receptors in the sciatic nerve and increases their density in the inflamed tissue, Neurosci., 55 (1993) 185-195.
13. Heberden, W., Commentaries on the history and cure of disease, Hafner, New York, 1962, p. 213.
14. Hermens, J.M., Ebertz, J.M., Hanifin, J.M. and Hirshman, C.A., Comparison of histamine release in human skin mast cells induced by morphine, fentanyl and oxymorphone, Anesthesiology, 62 (1985) 124-129.
15. Hughes, J., Peripheral opiate receptor mechanisms, Trends Pharmacol. Sci., 2 (1981) 21-24.
16. Karlsson, J.A., Lanner, A.S. and Persson, C.G.A., Airway opioid receptors mediate inhibition of cough and reflex bronchoconstriction in guinea pigs, J. Pharmacol. Exp. Therap., 252 (1990) 863-867.
17. Krajnik, M. and Zylicz, Z., Topical morphine for malignant cutaneous pain, Palliative. Med., 11 (1997a) 325.
18. Krajnik, M. and Zylicz, Z., Topical opioids - fact or fiction?, Prog. Palliative Care, 5 (1997b) 101-106.
19. Lawrence, A.J., Joshi, G.P., Michalkiewicz, A., Blunnie, W.P. and Moriarty, B.C., Evidence for analgesia mediated by peripheral opioid receptors in inflamed synovial tissue, Eur. J. Clin. Pharmacol., 43 (1992) 351-355.
20. Likar, R., Sittl, R., Gragger, K., Pert, C.B. and Snyder, S.H., Opiate receptors, its demonstration in nervous tissue, Science, 179 (1973) 1011-1014.
21. Likar, R., Schafer, M., Paulak, F., Sittl, R., Pipam, W., Schalk, H., Geissler, D. and Bernatzky, G., Intraarticular morphine analgesia in chronic pain patients with osteoarthritis, Anesth. Analg., 84 (1997) 1313-1317.
22. Likar, R., Sittl, R., Gragger, K., Pipam, H., Blanting, H., Breschan, C., Schalk, H.V., Stein, C. and Schäfer, M., Peripheral morphine analgesia in dental surgery, Pain, 76 (1998) 145-150.
23. Przewlocki, R., Hassan, A.H.S., Lason, W., Epplen, C., Herz, A. and Stein, C., Gene expression and localization of opioid peptides in immune cells of inflamed tissue: functional role in antinociception, Neurosci., 48 (1992) 491-500.
24. Roy, S.D. and Flynn, G.L., Transdermal delivery of narcotic analgesics: comparative permeabilities of narcotic analgesics through human cadaver skin, Pharm. Res., 6 (1989) 825-832.
25. Schäfer, M., Imai, Y., Uhl, G.R. and Stein, C., Inflammation enhances peripheral mu-opioid receptor-mediated analgesia, but not m-opioid receptor transcription in dorsal root ganglia, Eur. J. Pharmacol., 279 (1995) 165-169.
26. Sibinga, N.E.S. and Goldstein, A., Opioid peptides and opioid receptors in cells of the immune system, Annu. Rev. Immunol., 6 (1988) 219-249.
27. +-evoked release of substance P in rat peripheral airways, Abstracts, 8th Congress on Pain, IASP Press Seattle, WA, 1996, p. 455.
28. Stein, C., Hassan, A.H.S., Przewlocki, R., Gramsch, C., Peter, K. and Herz, A., Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation, Proc. Natl. Acad. Sci. USA, 87 (1990) 5935-5939.
29. Stein, C., Comisel, K., Haimerl, E., Yassouridis, A., Lehrberger, K., Herz, A. and Peter, K., Analgesic effect of intraarticular morphine after arthroscopic knee surgery, N. Engl. J. Med., 325 (1991) 1123-1126.
30. Stein, C., Hassan, A.H.S., Lehrberger, K., Giefing, J. and Yassouridis, A., Local analgesic effect of endogenous opioid peptides, Lancet, 342 (1993) 321-324.
31. Stein, C., Pfluger, M., Yassouridis, A., Hoeizi, J., Lehrberger, K. and Welte, C., No tolerance to peripheral morphine analgesia in presence of opioid expression in inflamed synovia, J. Clin. Invest., 98 (1996) 793-799.
32. Torebjork, E., Nociceptor dynamics in humans, In: G.F. Gebhart, D.L. Hammond and T.S. Jensen (Eds.), Proceedings of the 7th World Congress on Pain. Progress in Pain Research and Management, Vol 2, IASP Press, Seattle, WA, 1994, pp. 277-284.
33. 2+ release from an intracellular pool in myocytes and neurons, Circ. Res, 70 (1992) 66-81.
34. Wall, P.D., The mechanisms by which tissue damage and pain are related. Pain 1996 - An Updated Review. Refresher Course Syllabus (8th World Congress on Pain), IASP Press, Seattle, WA, 1996, pp. 123-126.
35. Watkins, L.R., Maier, S.F. and Goehler, L.E., Immune activation: the role of proinflammatory cytokines in inflammation, illness responses and pathological pain states, Pain, 63 (1995) 289-302.
36. Westerling, D., Hoglund, P., Lundin, S. and Svedman, P., Transdermal administration of morphine to healthy subjects, Br. J. Clin. Pharmac., 37 (1994) 571-576.
37. Willis, W.D., Signal transduction mechanisms. Pain 1996 - An Updated Review. Refresher Course Syllabus (8th World Congress on Pain), IASP Press, Seattle, WA, 1996, pp. 527-531.
38. Wood, A., New method of treating neuralgia by the direct application of opiates to the painful points, Edinburgh Med. Surg. J., 82 (1885) 265-281.
39. Zimlichman, R., Gefel, D., Eliahou, H., Matas, Z., Rosen, B., Gass, S., Ela, C., Eilam, Y., Vogel, Z. and Barg, J., Expression of opioid receptors during heart ontogeny in normotensive and hypertensive rats, Circulation, 93 (1996) 1020-1025.