Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females

Oncogene

Volumn 29, Issue 42, 2010, Pages 5678-5686

  Antico Arciuch, V G ^a   Dima, M ^a   Liao, X H ^b   Refetoff, S ^b   Di Cristofano, A ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

estrogen; Pten; thyroid cancer

Indexed keywords

ESTROGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; PTEN PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CANCER RISK; CANCER SURVIVAL; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; FEMALE; FOLLICULAR CARCINOMA; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOLECULAR INTERACTION; MOUSE; MUTANT; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; SEX DIFFERENCE; THYROID FOLLICULAR CARCINOMA; TUMOR SUPPRESSOR GENE; ADENOCARCINOMA; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETICS; INCIDENCE; METABOLISM; MUTANT MOUSE STRAIN; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEXUAL DEVELOPMENT; SIGNAL TRANSDUCTION; THYROID GLAND; THYROID TUMOR; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOCARCINOMA, FOLLICULAR; ANIMALS; BLOTTING, WESTERN; CYCLIN-DEPENDENT KINASE INHIBITOR P27; ESTROGENS; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; INCIDENCE; MALE; MICE; MICE, MUTANT STRAINS; PTEN PHOSPHOHYDROLASE; RECEPTOR CROSS-TALK; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEX CHARACTERISTICS; THYROID GLAND; THYROID NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES;

MUS;

EID: 77958510966     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.308     Document Type: Article

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