Post-stroke apathy and hypoperfusion in Basal ganglia: SPECT study

Cerebrovascular Diseases

Volumn 31, Issue 1, 2010, Pages 6-11

  Onoda, Keiichi ^a   Kuroda, Yoko ^a   Yamamoto, Yasushi ^b   Abe, Satoshi ^a   Oguro, Hiroaki ^a   Nagai, Atsushi ^a   Bokura, Hirokazu ^c   Yamaguchi, Shuhei ^a  

^a SHIMANE UNIVERSITY   (Japan)

^b SHIMANE UNIVERSITY HOSPITAL   (Japan)

^c SHIMANE PREFECTURAL CENTRAL HOSPITAL   (Japan)

Author keywords

Apathy; Basal ganglia; SPECT; Stroke

Indexed keywords

IOFETAMINE I 123;

ADULT; AGED; APATHY; ARTICLE; BASAL GANGLION; BRAIN BLOOD FLOW; BRAIN INFARCTION; BRAIN PERFUSION; COGNITION; CONTROLLED STUDY; DEPRESSION; FEMALE; FRONTAL CORTEX; FUNCTIONAL ASSESSMENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCIPITAL CORTEX; PARIETAL CORTEX; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STROKE; TEMPORAL CORTEX; THALAMUS;

AGED; AGED, 80 AND OVER; APATHY; BASAL GANGLIA; CEREBROVASCULAR CIRCULATION; CHI-SQUARE DISTRIBUTION; COGNITION; DEPRESSION; FEMALE; HUMANS; IOFETAMINE; JAPAN; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PERFUSION IMAGING; PSYCHIATRIC STATUS RATING SCALES; RADIOPHARMACEUTICALS; REGIONAL BLOOD FLOW; STROKE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 77958508190     PISSN: 10159770     EISSN: None     Source Type: Journal    
DOI: 10.1159/000319771     Document Type: Article

References (42)

1. Marin RS: Apathy: A neuropsychiatric syndrome. J Neuropsychiatry Clin Neurosci 1991;3:243-254.
2. Marin RS, Biedrzycki RC, Firinciogullari S: Reliability and validity of the apathy evaluation scale. Psychiatry Res 1991;38:143-162.
3. Ferro JM, Caeiro L, Santos C: Poststroke emotional and behavior impairment: a narrative review. Cerebrovasc Dis 2009;27(suppl 1):197-203.
4. Ishii S, Weintraub N, Mervis JR: Apathy: A common psychiatric syndrome in the elderly. J Am Med Dir Assoc 2009;10:381-393.
5. Orfei MD, Caltagirone C, Spalletta G: The evaluation of anosognosia in stroke patients. Cerebrovasc Dis 2009;27:280-289.
6. Kuzis G, Sabe L, Tiberti C, Dorrego F, Starkstein SE: Neuropsychological correlates of apathy and depression in patients with dementia. Neurology 1999;52:1403-1407.
7. Levy ML, Cummings JL, Fairbanks LA, Masterman D, Miller BL, Craig AH, Paulsen JS, Litvan I: Apathy is not depression. J Neuropsychiatry Clin Neurosci 1998;10:314-319.
8. Starkstein SE, Ingram L, Garau ML, Mizrahi R: On the overlap between apathy and depression in dementia. J Neurol Neurosurg Psychiatry 2005;76:1070-1074.
9. Brodaty H, Sachdev PS, Withall A, Altendorf A, Valenzuela MJ, Lorentz L: Frequency and clinical, neuropsychological and neuroimaging correlates of apathy following stroke: the Sydney stroke study. Psychol Med 2005;35:1707-1716.
10. Glodzik-Sobanska L, Slowik A, Kieltyka A, Kozub J, Sobiecka B, Urbanik A, Szczudlik A: Reduced prefrontal N-acetylaspartate in stroke patients with apathy. J Neurol Sci 2005;238:19-24.
11. Hama S, Yamashita H, Shigenobu M, Watanabe A, Hiramoto K, Kurisu K, Yamawaki S, Kitaoka T: Depression or apathy and functional recovery after stroke. Int J Geriatr Psychiatry 2007;22:1046-1051.
12. Mayo NE, Fellows LK, Scott SC, Cameron J, Wood-Dauphinee S: A longitudinal view of apathy and its impact after stroke. Stroke 2009;40:3299-3307.
13. Piamarta F, Iurlaro S, Isella V, Atzeni L, Grimaldi M, Russo A, Forapani E, Appollonio I: Unconventional affective symptoms and executive functions after stroke in the elderly. Arch Gerontol Geriatr Suppl 2004;9:315-323.
14. Starkstein SE, Fedoroff JP, Price TR, Leiguarda R, Robinson RG: Apathy following cerebrovascular lesions. Stroke 1993;24:1625-1630.
15. Bonelli RM, Cummings JL: Frontal-subcortical circuitry and behavior. Dialogues Clin Neurosci 2007;9:141-151.
16. Tekin S, Cummings JL: Frontal-subcortical neuronal circuits and clinical neuropsychiatry: an update. J Psychosom Res 2002;53:647-654.
17. Benoit M, Clairet S, Koulibaly PM, Darcourt J, Robert PH: Brain perfusion correlates of the apathy inventory dimensions of Alzheimer's disease. Int J Geriatr Psychiatry 2004;19:864-869.
18. Benoit M, Dygai I, Migneco O, Robert PH, Bertogliati C, Darcourt J, Benoliel J, Aubin-Brunet V, Pringuey D: Behavioral and psychological symptoms in Alzheimer's disease: relation between apathy and regional cerebral perfusion. Dement Geriatr Cogn Disord 1999;10:511-517.
19. Benoit M, Koulibaly PM, Migneco O, Darcourt J, Pringuey DJ, Robert PH: Brain perfusion in Alzheimer's disease with and without apathy: a SPECT study with statistical parametric mapping analysis. Psychiatry Res 2002;114:103-111.
20. Lanctot KL, Moosa S, Herrmann N, Leibovitch FS, Rothenburg L, Cotter A, Black SE: A SPECT study of apathy in Alzheimer's disease. Dement Geriatr Cogn Disord 2007;24:65-72.
21. Lopez OL, Zivkovic S, Smith G, Becker JT, Meltzer CC, DeKosky ST: Psychiatric symptoms associated with cortical-subcortical dysfunction in Alzheimer's disease. J Neuropsychiatry Clin Neurosci 2001;13:56-60.
22. Migneco O, Benoit M, Koulibaly PM, Dygai I, Bertogliati C, Desvignes P, Robert PH, Malandain G, Bussiere F, Darcourt J: Perfusion brain SPECT and statistical parametric mapping analysis indicate that apathy is a cingulate syndrome: a study in Alzheimer's disease and nondemented patients. Neuroimage 2001;13:896-902.
23. Robert PH, Darcourt G, Koulibaly MP, Clairet S, Benoit M, Garcia R, Dechaux O, Darcourt J: Lack of initiative and interest in Alzheimer's disease: a single photon emission computed tomography study. Eur J Neurol 2006;13:729-735.
24. Okada K, Kobayashi S, Yamagata S, Takahashi K, Yamaguchi S: Poststroke apathy and regional cerebral blood flow. Stroke 1997;28:2437-2441.
25. Roman GC, Tatemichi TK, Erkinjuntti T, Cummings JL, Masdeu JC, Garcia JH, Amaducci L, Orgogozo JM, Brun A, Hofman A, et al: Vascular dementia: diagnostic criteria for research studies. Report of the NINDSAIREN international workshop. Neurology 1993;43:250-260.
26. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM: Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services task force on Alzheimer's disease. Neurology 1984;34:939-944.
27. Shinohara Y, Minematsu K, Amano T, Ohashi Y: Modified Rankin scale with expanded guidance scheme and interview questionnaire: interrater agreement and reproducibility of assessment. Cerebrovasc Dis 2006;21:271-278.
28. Okada K, Kobayashi S, Aoki K, Suyama N, Yamagata S: Assessment of motivational loss in poststroke patients using the Japanese version of Starkstein's Apathy Scale (in Japanese). Jpn J Stroke 1998;20:318-327.
29. Starkstein SE, Mayberg HS, Preziosi TJ, Andrezejewski P, Leiguarda R, Robinson RG: Reliability, validity, and clinical correlates of apathy in Parkinson's disease. J Neuropsychiatry Clin Neurosci 1992;4:134-139.
30. Folstein MF, Folstein SE, McHugh PR: 'Mini-mental state': a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198.
31. Katou S, Onodera A, Ueda H, Oikawa K, Ikeda K, Kosaka A, Imai Y, Hasegawa K: Development of the revised version of Hasegewa's dementia scale. Japanese J Geriat Psychiatry 1991;2:1339-1347.
32. Dubois B, Slachevsky A, Litvan I, Pillon B: The FAB: a frontal assessment battery at bedside. Neurology 2000;55:1621-1626.
33. Zung WW: A self-rating depression scale. Arch Gen Psychiatry 1965;12:63-70.
34. Okamoto K, Ushijima Y, Okuyama C, Nakamura T, Nishimura T: Measurement of cerebral blood flow using graph plot analysis and i-123 iodoamphetamine. Clin Nucl Med 2002;27:191-196.
35. Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH: An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 2003;19:1233-1239.
36. Andersson S, Krogstad JM, Finset A: Apathy and depressed mood in acquired brain damage: relationship to lesion localization and psychophysiological reactivity. Psychol Med 1999;29:447-456.
37. Erhan H, Ochoa E, Borod J, Feinberg T: Consequences of right cerebrovascular accident on emotional functioning: diagnostic and treatment implications. CNS Spectr 2000;5:25-38.
38. Marin RS, Firinciogullari S, Biedrzycki RC: The sources of convergence between measures of apathy and depression. J Affect Disord 1993;28:117-124. (Pubitemid 23178099)
39. Yamagata S, Yamaguchi S, Kobayashi S: Impaired novelty processing in apathy after subcortical stroke. Stroke 2004;35:1935-1940.
40. David R, Koulibaly M, Benoit M, Garcia R, Caci H, Darcourt J, Robert P: Striatal dopamine transporter levels correlate with apathy in neurodegenerative diseases a SPECT study with partial volume effect correction. Clin Neurol Neurosurg 2008;110:19-24.
41. Kohno N, Abe A, Toyoda G, Oruro H, Bokura H, Yamaguchi S: Successful treatment of post-stroke apathy by dopamine receptor agonist ropinirole. J Cli Neurosci 2010;17:804-806.
42. Reyes S, Viswanathan A, Godin O, Dufouil C, Benisty S, Hernandez K, Kurtz A, Jouvent E, O'Sullivan M, Czernecki V, Bousser MG, Dichgans M, Chabriat H: Apathy: a major symptom in cadasil. Neurology 2009;72:905-910.