ERβ expression in normal, adenomatous and carcinomatous tissues of patients with familial adenomatous polyposis

Scandinavian Journal of Gastroenterology

Volumn 45, Issue 11, 2010, Pages 1320-1328

  Barone, Michele ^a   Scavo, Maria Principia ^a   Papagni, Samanta ^a   Piscitelli, Domenico ^a   Guido, Raffaella ^a   Di Lena, Maria ^a   Comelli, Maria Cristina ^b   Di Leo, Alfredo ^a  

^a UNIVERSITY OF BARI   (Italy)

^b CM and D Pharma Limited   (United Kingdom)

Author keywords

Colon cancer; Estrogen receptor; Familial adenomatous polyposis

Indexed keywords

BIOLOGICAL MARKER; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA;

ADENOMATOUS POLYP; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; COLON RESECTION; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE MUTATION; HUMAN; HUMAN TISSUE; INTESTINE MUCOSA; MALE; NICK END LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH;

ADENOCARCINOMA; ADENOMATOUS POLYPOSIS COLI; ADULT; APOPTOSIS; BIOPSY; CELL PROLIFERATION; COLON, DESCENDING; COLORECTAL NEOPLASMS; DISEASE PROGRESSION; DNA, NEOPLASM; ESTROGEN RECEPTOR BETA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IN SITU NICK-END LABELING; INTESTINAL MUCOSA; MALE; PROGNOSIS; SEVERITY OF ILLNESS INDEX;

EID: 77958483597     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2010.487915     Document Type: Article

References (28)

1. Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, et al. Genetic alterations during colorectal-tumor development. N Engl J Med 1988;319: 525-532
2. Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996;87:159-170
3. Di Leo A, Messa C, Russo F, Misciagna G, Guerra V, Taveri R, et al. Prognostic value of cytosolic estrogen receptors in human colorectal carcinoma and surrounding mucosa. Preliminary results. Dig Dis Sci 1994;39:2038-2042
4. Fernandez E, La Vecchia C, Braga C, Talamini R, Negri E, Parazzini F, et al. Hormone replacement therapy and risk of colon and rectal cancer. Cancer Epidemiol Biomarkers Prev 1998;7:329-333
5. Notarnicola M, Gristina R, Messa C, Cariola F, Fiorente P, Caruso ML, et al. Oestrogen receptors and microsatellite instability in colorectal cancer patients. Cancer Lett 2001; 168:65-70.
6. Tangrea JA, Albert PS, Lanza E, Woodson K, Corle D, Hasson M, et al. Hormone replacement therapy and colorectal adenoma recurrence among women in the polyp prevention trial. Report J Natl Cancer Inst 2001;93:1799-1805
7. Newcomb PA, Storer BE. Postmenopausal hormone replacement therapy: scientific review. JAMA 2002;110:219-227
8. Weyant MJ, Carothers AM, Mahmoud NN, Bradlow HL, Remotti H, Bilinski RT, et al. Reciprocal expression of ERa and ERb is associated with estrogen-mediated modulation of intestinal tumorigenesis. Cancer Res 2001;61:2547-2551
9. Javid SH, Moran AE, Carothers AM, Redston M, Bertagnolli MM. Modulation of tumor formation and intestinal cell migration by estrogens in the ApcMin/+ mouse model of colorectal cancer. Carcinogenesis 2005;26:587-595
10. Giroux V, Lemay F, Bernatchez G, Robitaille Y, Carrier JC. Estrogen receptor beta deficiency enhances small intestinal tumorigenesis in ApcMin/+ mice. Int J Cancer 2008;123: 303-311
11. Barone M, Tanzi S, Lofano K, Scavo MP, Pricci M, Demarinis L, et al. Dietary-induced ERb upregulation counteracts intestinal neoplasia development in intact male ApcMin/+ mice. Carcinogenesis 2010;31:269-274
12. Bardin A, Boulle N, Lazennec G, Vignon F, Pujol P, et al. Loss of ERbeta expression as a common step in estrogendependent tumor progression. Endocr Relat Cancer 2004; 11:537-551
13. Jassam N, Bell SM, Speirs V, Quirke P. Loss of expression of oestrogen receptor beta in colon cancer and its association with Dukes' staging. Oncol Rep 2005;14:17-21.
14. Kennelly R, Kavanagh DO, Hogan AM, Winter DC. Oestrogen and the colon: potential mechanisms for cancer prevention. Lancet Oncol 2008;9:385-391
15. Talbot IC, Burt R, Jarvinen H, Thomas G. Familial Adenomatous Polyposis (FAP), pathology and genetics of tumors of the digestive system. In: Stanley R, Hamilton Lauri A, editor. Aaltonen: IARC Press Lyon; 2000. pp 120-125
16. Cattoretti G, Becker MHG, Key G, Duchrow M, Schlüter C, Galtet J. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 e MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin section. J Pathol 1992;168:357-363
17. Parkin DM. International variation. Oncogene 2004;23: 6329-6340
18. Bisgaard ML, Fenger K, Bülow S, Niebuhr E, Mohr J. Familial adenomatous polyposis (FAP): frequency, penetrance, and mutation rate. Hum Mutat 1994;3:121-125
19. Miyoshi Y, Nagase H, Ando H, Horii A, Ichii S, Nakatsuru S, et al. Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum Mol Genet 1992;1:229-233
20. Giles RH, van Es JH, Clevers H. Caught up in a Wnt storm: Wnt signaling in cancer. Biochim Biophys Acta 2003; 1:1-24.
21. Fearnhead NS. The ABC of the APC. Hum Mol Genet 2001;7:721-733.
22. Cho NL, Javid SH, Carothers AM, Redston M, Bertagnolli MM. Estrogen receptors alpha and beta are inhibitory modifiers of Apc-dependent tumorigenesis in the proximal colon of Min/+ mice. Cancer Res 2007;67: 2366-2372
23. Cleveland AG, Oikarinen SI, Bynoté KK, Marttinen M, Rafter JJ, Gustafsson JA, et al. Disruption of estrogen receptor signaling enhances intestinal neoplasia in APCMin/+ Mice. Carcinogenesis 2009;30:1581-1590
24. Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, et al. Risk and benefit of estrogen plus progestin in health postmenopausal women: principals results from the Women's Health Initiative randomized controlled trial. JAMA 2002;3:321-333
25. Qiu Y, Waters CE, Lewis AE, Langman MJ, Eggo MC. Oestrogen induced apoptosis in colonocytes expressing oestrogen receptor beta. J Endocrinol 2002;174:369-377
26. Ierardi E, Di Leo A, Barone M, Marangi S, Burattini O, Panarese A, et al. Tumor necrosis factor alpha and apoptosis in Helicobacter pylori related progressive gastric damage a possible mechanism of immune system involvement in epithelial turnover regulation. Immunopharmacol Immunotoxicol 2003;25:203-211
27. Gieseler F, Rudolph P, Kloeppel G, Foelsch UR. Resistance mechanism of gastrointestinal cancers: why does conventional chemotherapy fail? Int J Colorectal Dis 2003;18: 470-480.
28. Pereira MA, Tao L, Wang W, Li Y, Umar A, Steele VE, et al. Modulation by celecoxib and difluoromethylornithine of the methylation of DNA and the estrogen receptor- a gene in rat colon tumors. Carcinogenesis 2004;25:1917-1923