Retinoic acid receptor-α signalling antagonizes both intracellular and extracellular amyloid-β production and prevents neuronal cell death caused by amyloid-β

European Journal of Neuroscience

Volumn 32, Issue 8, 2010, Pages 1246-1255

  Jarvis, C I ^a   Goncalves, M B ^a   Clarke, E ^a   Dogruel, M ^a   Kalindjian, S B ^a   Thomas, S A ^a   Maden, M ^a   Corcoran, J P T ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

ADAM10; Alzheimer's disease; Neuronal survival; RAR ; Retinoic acid; Small molecule

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; DISINTEGRIN; HEPARIN; METALLOPROTEINASE; NEUROPROTECTIVE AGENT; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR ALPHA AGONIST; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; RETINOID; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; BRAIN CORTEX; BRAIN PERFUSION; EMBRYO; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ADAM PROTEINS; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANALYSIS OF VARIANCE; ANIMALS; BENZOATES; BLOTTING, WESTERN; CELL DEATH; CEREBRAL CORTEX; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PROTEINS; MICE; NEURONS; RECEPTORS, RETINOIC ACID; RETINOIDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TETRAHYDRONAPHTHALENES;

EID: 77958480110     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2010.07426.x     Document Type: Article

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