-
1
-
-
43249115659
-
Randomized phase III trial of weekly compared with every-3-weeks paclitaxel for metastatic breast cancer, with trastuzumab for all HER-2 overexpressors and random assignment to trastuzumab or not in HER-2 nonoverexpressors: final results of Cancer and Leukemia Group B protocol 9840
-
Seidman AD, Berry D, Cirrincione C et al. Randomized phase III trial of weekly compared with every-3-weeks paclitaxel for metastatic breast cancer, with trastuzumab for all HER-2 overexpressors and random assignment to trastuzumab or not in HER-2 nonoverexpressors: final results of Cancer and Leukemia Group B protocol 9840. J Clin Oncol 2008; 26(10): 1642-1649.
-
(2008)
J Clin Oncol
, vol.26
, Issue.10
, pp. 1642-1649
-
-
Seidman, A.D.1
Berry, D.2
Cirrincione, C.3
-
2
-
-
40449109379
-
Novel taxane formulations in the treatment of breast cancer: a thought leader discussion and consensus roundtable
-
Gralow J, Rugo H, Gradishar W et al. Novel taxane formulations in the treatment of breast cancer: a thought leader discussion and consensus roundtable. Clin Breast Cancer 2008; 8(1): 33-37.
-
(2008)
Clin Breast Cancer
, vol.8
, Issue.1
, pp. 33-37
-
-
Gralow, J.1
Rugo, H.2
Gradishar, W.3
-
3
-
-
0031671094
-
Phase I and pharmacologic study of intermittent twice-daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer
-
Mackean M, Planting A, Twelves C et al. Phase I and pharmacologic study of intermittent twice-daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer. J Clin Oncol 1998; 16(9): 2977-2985.
-
(1998)
J Clin Oncol
, vol.16
, Issue.9
, pp. 2977-2985
-
-
Mackean, M.1
Planting, A.2
Twelves, C.3
-
4
-
-
0034016343
-
Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study
-
Van Cutsem E, Findlay M, Osterwalder B et al. Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study. J Clin Oncol 2000; 18(6): 1337-1345.
-
(2000)
J Clin Oncol
, vol.18
, Issue.6
, pp. 1337-1345
-
-
Van Cutsem, E.1
Findlay, M.2
Osterwalder, B.3
-
5
-
-
43749111108
-
Potential regional differences for the tolerability profiles of fluoropyrimidines
-
Haller DG, Cassidy J, Clarke SJ et al. Potential regional differences for the tolerability profiles of fluoropyrimidines. J Clin Oncol 2008; 26(13): 2118-2123.
-
(2008)
J Clin Oncol
, vol.26
, Issue.13
, pp. 2118-2123
-
-
Haller, D.G.1
Cassidy, J.2
Clarke, S.J.3
-
6
-
-
0033050165
-
Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer
-
Blum JL, Jones SE, Buzdar AU et al. Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol 1999; 17(2): 485-493.
-
(1999)
J Clin Oncol
, vol.17
, Issue.2
, pp. 485-493
-
-
Blum, J.L.1
Jones, S.E.2
Buzdar, A.U.3
-
7
-
-
0035476911
-
Multicenter, phase II study of capecitabine in taxane-pretreated metastatic breast carcinoma patients
-
Blum JL, Dieras V, Lo Russo PM et al. Multicenter, phase II study of capecitabine in taxane-pretreated metastatic breast carcinoma patients. Cancer 2001; 92(7): 1759-1768.
-
(2001)
Cancer
, vol.92
, Issue.7
, pp. 1759-1768
-
-
Blum, J.L.1
Dieras, V.2
Lo Russo, P.M.3
-
8
-
-
0041508753
-
Multicenter phase II study of oral capecitabine (Xeloda(")) in patients with metastatic breast cancer relapsing after treatment with a taxane-containing therapy
-
Reichardt P, Von Minckwitz G, Thuss-Patience PC et al. Multicenter phase II study of oral capecitabine (Xeloda(")) in patients with metastatic breast cancer relapsing after treatment with a taxane-containing therapy. Ann Oncol 2003; 14(8): 1227-1233.
-
(2003)
Ann Oncol
, vol.14
, Issue.8
, pp. 1227-1233
-
-
Reichardt, P.1
Von Minckwitz, G.2
Thuss-Patience, P.C.3
-
9
-
-
10744229320
-
Multicentre, phase II study evaluating capecitabine monotherapy in patients with anthracycline and taxane-pretreated metastatic breast cancer
-
Fumoleau P, Largillier R, Clippe C et al. Multicentre, phase II study evaluating capecitabine monotherapy in patients with anthracycline and taxane-pretreated metastatic breast cancer. Eur J Cancer 2004; 40(4): 536-542.
-
(2004)
Eur J Cancer
, vol.40
, Issue.4
, pp. 536-542
-
-
Fumoleau, P.1
Largillier, R.2
Clippe, C.3
-
10
-
-
34548294224
-
Capecitabine (X) monotherapy after anthracycline and taxane failure in metastatic breast cancer (MBC): long-term survival data
-
(Abstr 161P)
-
Largillier R, Fumoleau P, Clippe C et al. Capecitabine (X) monotherapy after anthracycline and taxane failure in metastatic breast cancer (MBC): long-term survival data. Ann Oncol 2006; 17(Suppl 9): ix74 (Abstr 161P).
-
(2006)
Ann Oncol
, vol.17
, Issue.SUPPL 9
-
-
Largillier, R.1
Fumoleau, P.2
Clippe, C.3
-
11
-
-
20044364346
-
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
-
Miller KD, Chap LI, Holmes FA et al. Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 2005; 23: 792-799.
-
(2005)
J Clin Oncol
, vol.23
, pp. 792-799
-
-
Miller, K.D.1
Chap, L.I.2
Holmes, F.A.3
-
12
-
-
36849071808
-
Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment
-
Thomas ES, Gomez HL, Li RK et al. Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment. J Clin Oncol 2007; 25(33): 5210-5217.
-
(2007)
J Clin Oncol
, vol.25
, Issue.33
, pp. 5210-5217
-
-
Thomas, E.S.1
Gomez, H.L.2
Li, R.K.3
-
13
-
-
33845886440
-
Lapatinib plus capecitabine for HER2 positive advanced breast cancer
-
Geyer CE, Forster J, Lindquist D et al. Lapatinib plus capecitabine for HER2 positive advanced breast cancer. N Engl J Med 2006; 355: 2733-2743.
-
(2006)
N Engl J Med
, vol.355
, pp. 2733-2743
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
-
15
-
-
34548225937
-
A multicenter randomized study comparing vinorelbine plus gemcitabine versus capecitabine monotherapy as salvage treatment in patients with advanced breast cancer pretreated with taxane and anthracycline chemotherapy: a preliminary report
-
Mavroudis D, Ardavanis A, Boukovinas I et al. A multicenter randomized study comparing vinorelbine plus gemcitabine versus capecitabine monotherapy as salvage treatment in patients with advanced breast cancer pretreated with taxane and anthracycline chemotherapy: a preliminary report. J Clin Oncol 2006; 24(18S): 658.
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S
, pp. 658
-
-
Mavroudis, D.1
Ardavanis, A.2
Boukovinas, I.3
-
16
-
-
34249892537
-
Intermittent capecitabine monotherapy with lower dose intensity in heavily pretreated patients with metastatic breast cancer
-
Osako T, Ito Y, Takahashi S et al. Intermittent capecitabine monotherapy with lower dose intensity in heavily pretreated patients with metastatic breast cancer. Tumori 2007; 93(2): 129-132.
-
(2007)
Tumori
, vol.93
, Issue.2
, pp. 129-132
-
-
Osako, T.1
Ito, Y.2
Takahashi, S.3
-
17
-
-
33846247078
-
Efficacy of lower dose capecitabine in patients with metastatic breast cancer and factors influencing therapeutic response and outcome
-
Sezgin C, Kurt E, Evrensel T et al. Efficacy of lower dose capecitabine in patients with metastatic breast cancer and factors influencing therapeutic response and outcome. South Med J 2007; 100(1): 27-32.
-
(2007)
South Med J
, vol.100
, Issue.1
, pp. 27-32
-
-
Sezgin, C.1
Kurt, E.2
Evrensel, T.3
-
18
-
-
23844449433
-
Lower dose capecitabine has a more favorable therapeutic index in metastatic breast cancer: retrospective analysis of patients treated at M D. Anderson Cancer Center and a review of capecitabine toxicity in the literature
-
Hennessy BT, Gauthier AM, Michaud LB et al. Lower dose capecitabine has a more favorable therapeutic index in metastatic breast cancer: retrospective analysis of patients treated at M.D. Anderson Cancer Center and a review of capecitabine toxicity in the literature. Ann Oncol 2005; 16(8): 1289-1296.
-
(2005)
Ann Oncol
, vol.16
, Issue.8
, pp. 1289-1296
-
-
Hennessy, B.T.1
Gauthier, A.M.2
Michaud, L.B.3
-
19
-
-
0002640816
-
on behalf of the Xeloda Breast Cancer Study Group Capecitabine in 162 patients with paclitaxel-pretreated MBC: updated results and analysis of dose modification
-
(Abstr 693)
-
Blum JL, Jones SE, Buzdar AU. on behalf of the Xeloda Breast Cancer Study Group. Capecitabine in 162 patients with paclitaxel-pretreated MBC: updated results and analysis of dose modification. Eur J Cancer 2001; 37 (Suppl 6): 190 (Abstr 693).
-
(2001)
Eur J Cancer
, vol.37
, Issue.SUPPL 6
, pp. 190
-
-
Blum, J.L.1
Jones, S.E.2
Buzdar, A.U.3
-
20
-
-
0034778024
-
Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer
-
O'Shaughnessy JA, Blum J, Moiseyenko V et al. Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer. Ann Oncol 2001; 12(9): 1247-1254.
-
(2001)
Ann Oncol
, vol.12
, Issue.9
, pp. 1247-1254
-
-
O'Shaughnessy, J.A.1
Blum, J.2
Moiseyenko, V.3
-
21
-
-
20244368234
-
Safety and efficacy of two different doses of capecitabine in the treatment of advanced breast cancer in older women
-
Bajetta E, Procopio G, Celio L et al. Safety and efficacy of two different doses of capecitabine in the treatment of advanced breast cancer in older women. J Clin Oncol 2005; 23(10): 2155-2161.
-
(2005)
J Clin Oncol
, vol.23
, Issue.10
, pp. 2155-2161
-
-
Bajetta, E.1
Procopio, G.2
Celio, L.3
-
22
-
-
41849091764
-
A randomized trial of capecitabine (C) given intermittently (IC) rather than continuously (CC) compared to classical CMF as first-line chemotherapy for advanced breast cancer (ABC)
-
Stockler MR, Sourjina T, Grimison P et al. A randomized trial of capecitabine (C) given intermittently (IC) rather than continuously (CC) compared to classical CMF as first-line chemotherapy for advanced breast cancer (ABC). J Clin Oncol 2007; 25(18S): 1031.
-
(2007)
J Clin Oncol
, vol.25
, Issue.18 S
, pp. 1031
-
-
Stockler, M.R.1
Sourjina, T.2
Grimison, P.3
-
23
-
-
70249097518
-
RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab (B) for first-line treatment of HER2-negative locally recurrent or metastatic breast cancer (MBC)
-
(Abstr 1005)
-
Robert NJ, Dieras V, Glaspy J et al. RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab (B) for first-line treatment of HER2-negative locally recurrent or metastatic breast cancer (MBC). J Clin Oncol 2009; 27(15S): 42s (Abstr 1005).
-
(2009)
J Clin Oncol
, vol.27
, Issue.15 S
-
-
Robert, N.J.1
Dieras, V.2
Glaspy, J.3
-
24
-
-
77952291875
-
MoniCa: a multicenter phase II study to determine the efficacy of capecitabine as first line monochemotherapy in patients with HER2 negative, medium-risk, metastatic breast cancer (GBG39)
-
(Abstr 5002)
-
Kaufmann M, Sütterlin MW, Schrader I et al. MoniCa: a multicenter phase II study to determine the efficacy of capecitabine as first line monochemotherapy in patients with HER2 negative, medium-risk, metastatic breast cancer (GBG39). Eur J Cancer Suppl 2009; 7: 260 (Abstr 5002).
-
(2009)
Eur J Cancer Suppl
, vol.7
, pp. 260
-
-
Kaufmann, M.1
Sutterlin, M.W.2
Schrader, I.3
-
25
-
-
70450208728
-
First-line capecitabine monotherapy for slowly progressing metastatic breast cancer: do we need aggressive treatment?
-
Debled M, Madranges N, Trainaud A et al. First-line capecitabine monotherapy for slowly progressing metastatic breast cancer: do we need aggressive treatment? Oncology 2009; 77: 318-327.
-
(2009)
Oncology
, vol.77
, pp. 318-327
-
-
Debled, M.1
Madranges, N.2
Trainaud, A.3
-
26
-
-
34547202465
-
Clinical efficacy of capecitabine as first-line chemotherapy in metastatic breast cancer-how low can you go?
-
Yap YS, Kendall A, Walsh G et al. Clinical efficacy of capecitabine as first-line chemotherapy in metastatic breast cancer-how low can you go? Breast 2007; 16(4): 420-424.
-
(2007)
Breast
, vol.16
, Issue.4
, pp. 420-424
-
-
Yap, Y.S.1
Kendall, A.2
Walsh, G.3
-
27
-
-
0000396108
-
A retrospective evaluation of the impact of dose reduction in patients treated with Xeloda (capecitabine)
-
(Abstr 400)
-
O'Shaughnessy J, Blum J. A retrospective evaluation of the impact of dose reduction in patients treated with Xeloda (capecitabine). Proc Am Soc Clin Oncol 2000; 19: (Abstr 400).
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
O'Shaughnessy, J.1
Blum, J.2
-
28
-
-
0036302297
-
Potential of capecitabine as first-line therapy for metastatic breast cancer: dosing recommendations in patients with diminished renal function
-
O'Shaughnessy JA. Potential of capecitabine as first-line therapy for metastatic breast cancer: dosing recommendations in patients with diminished renal function. Ann Oncol 2002; 13(6): 983.
-
(2002)
Ann Oncol
, vol.13
, Issue.6
, pp. 983
-
-
O'Shaughnessy, J.A.1
-
29
-
-
38049035076
-
Safety profile and activity of lower capecitabine dose in patients with metastatic breast cancer
-
Rossi D, Alessandroni P, Catalano V et al. Safety profile and activity of lower capecitabine dose in patients with metastatic breast cancer. Clin Breast Cancer 2007; 7(11): 857-860.
-
(2007)
Clin Breast Cancer
, vol.7
, Issue.11
, pp. 857-860
-
-
Rossi, D.1
Alessandroni, P.2
Catalano, V.3
-
30
-
-
27144459653
-
Reduced dose capecitabine is an effective and well-tolerated treatment in patients with metastatic breast cancer
-
El-Helw L, Coleman RE. Reduced dose capecitabine is an effective and well-tolerated treatment in patients with metastatic breast cancer. Breast 2005; 14(5): 368-374.
-
(2005)
Breast
, vol.14
, Issue.5
, pp. 368-374
-
-
El-Helw, L.1
Coleman, R.E.2
-
31
-
-
60549093408
-
Thymidine phosphorylase expression and benefit from capecitabine in patients with advanced breast cancer
-
Andreetta C, Puppin C, Minisini A et al. Thymidine phosphorylase expression and benefit from capecitabine in patients with advanced breast cancer. Ann Oncol 2009; 20(2): 265-271.
-
(2009)
Ann Oncol
, vol.20
, Issue.2
, pp. 265-271
-
-
Andreetta, C.1
Puppin, C.2
Minisini, A.3
-
32
-
-
77958479212
-
Randomized, phase II trial comparing continuous versus intermittent capecitabine monotherapy for metastatic breast cancer (MBC)
-
Martin M, Calvo L, Martinez N et al. Randomized, phase II trial comparing continuous versus intermittent capecitabine monotherapy for metastatic breast cancer (MBC). J Clin Oncol 2009; 27(15s): 1086.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15 S
, pp. 1086
-
-
Martin, M.1
Calvo, L.2
Martinez, N.3
-
33
-
-
33646694562
-
A pilot phase II study of capecitabine in advanced or recurrent breast cancer
-
Saeki T, Kimura T, Toi M, Taguchi T. A pilot phase II study of capecitabine in advanced or recurrent breast cancer. Breast Cancer 2006; 13(1): 49-57.
-
(2006)
Breast Cancer
, vol.13
, Issue.1
, pp. 49-57
-
-
Saeki, T.1
Kimura, T.2
Toi, M.3
Taguchi, T.4
-
34
-
-
0003277724
-
A multicenter phase II trial of XelodaTM (capecitabine) in patients with docetaxel-refractory advanced/metastatic breast cancer
-
(Abstr 1991)
-
Watanabe T, Katsumata N, Sasaki Y et al. A multicenter phase II trial of XelodaTM (capecitabine) in patients with docetaxel-refractory advanced/metastatic breast cancer. Proc Am Soc Clin Oncol 2001; 20: (Abstr 1991).
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
-
-
Watanabe, T.1
Katsumata, N.2
Sasaki, Y.3
-
35
-
-
77958094823
-
Phase II study of 4-weekly capecitabine monotherapy in advanced/metastatic breast cancer
-
[Epub ahead of print]
-
Kusama M, Nomizu T, Aogi K et al. Phase II study of 4-weekly capecitabine monotherapy in advanced/metastatic breast cancer. Breast Cancer 2009 [Epub ahead of print].
-
(2009)
Breast Cancer
-
-
Kusama, M.1
Nomizu, T.2
Aogi, K.3
-
36
-
-
74549122694
-
A novel capecitabine dosing schedule combined with bevacizumab is safe and active in patients with metastatic breast cancer: a phase II study
-
(Abstr 1101)
-
Traina T, Theodoulou M, Dugan U et al. A novel capecitabine dosing schedule combined with bevacizumab is safe and active in patients with metastatic breast cancer: a phase II study. J Clin Oncol 2008; 26 (Suppl): (66s Abstr 1101).
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL
-
-
Traina, T.1
Theodoulou, M.2
Dugan, U.3
-
37
-
-
42949171085
-
Phase I study of a novel capecitabine schedule based on the Norton-Simon mathematical model in patients with metastatic breast cancer
-
Traina TA, Theodoulou M, Feigin K et al. Phase I study of a novel capecitabine schedule based on the Norton-Simon mathematical model in patients with metastatic breast cancer. J Clin Oncol 2008; 26(11): 1797-1-802.
-
(2008)
J Clin Oncol
, vol.26
, Issue.11
, pp. 1797-1801
-
-
Traina, T.A.1
Theodoulou, M.2
Feigin, K.3
-
38
-
-
84898698983
-
Randomized study evaluating an alternative schedule of capecitabine (X) as monotherapy for metastatic breast cancer (MBC): safety and pharmacokinetic (PK) results
-
(Abstr 188)
-
Levy E, Pierga J, Largillier R et al. Randomized study evaluating an alternative schedule of capecitabine (X) as monotherapy for metastatic breast cancer (MBC): safety and pharmacokinetic (PK) results. ASCO Breast Cancer Symposium 2008 (Abstr 188).
-
(2008)
ASCO Breast Cancer Symposium
-
-
Levy, E.1
Pierga, J.2
Largillier, R.3
-
39
-
-
65349110371
-
Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a German breast group 26/breast international group 03-05 study
-
von Minckwitz G, du Bois A, Schmidt M et al. Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a German breast group 26/breast international group 03-05 study. J Clin Oncol 2009; 27(12): 1999-2006.
-
(2009)
J Clin Oncol
, vol.27
, Issue.12
, pp. 1999-2006
-
-
von Minckwitz, G.1
du Bois, A.2
Schmidt, M.3
-
40
-
-
33749356788
-
Pharmacogenetics of capecitabine in advanced breast cancer patients
-
Largillier R, Etienne-Grimaldi MC, Formento JL et al. Pharmacogenetics of capecitabine in advanced breast cancer patients. Clin Cancer Res 2006; 12(18): 5496-5502.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.18
, pp. 5496-5502
-
-
Largillier, R.1
Etienne-Grimaldi, M.C.2
Formento, J.L.3
-
41
-
-
45249110175
-
A carboxylesterase 2 gene polymorphism as predictor of capecitabine on response and time to progression
-
Ribelles N, López-Siles J, Sánchez A et al. A carboxylesterase 2 gene polymorphism as predictor of capecitabine on response and time to progression. Curr Drug Metab 2008; 9(4): 336-343.
-
(2008)
Curr Drug Metab
, vol.9
, Issue.4
, pp. 336-343
-
-
Ribelles, N.1
Lopez-Siles, J.2
Sanchez, A.3
|