Gain of cellular adaptation due to prolonged p53 impairment leads to functional switchover from p53 to p73 during DNA damage in acute myeloid leukemia cells

Journal of Biological Chemistry

Volumn 285, Issue 43, 2010, Pages 33104-33112

  Chakraborty, Juni ^a   Banerjee, Shuvomoy ^a   Ray, Pallab ^a   Hossain, Dewan Md Sakib ^a   Bhattacharyya, Sankar ^a   Adhikary, Arghya ^a   Chattopadhyay, Sreya ^a   Das, Tanya ^a   Sa, Gaurisankar ^a  

^a BOSE INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE MYELOID LEUKEMIA; ANTAGONISTIC INTERACTIONS; APOPTOSIS; CANCER CELLS; CANCER THERAPY; CELLULAR ADAPTATION; CELLULAR MICROENVIRONMENT; DNA DAMAGES; DOMINANT NEGATIVE; DOWN-REGULATION; ECTOPIC EXPRESSIONS; EVOLUTIONARY PERSPECTIVE; EXPERIMENTAL APPROACHES; GENOTOXIC STRESS; INDUCED APOPTOSIS; P53 FUNCTION; REGULATORY PROTEIN; SWITCHOVER; TUMOR SUPPRESSORS; WILD TYPES;

CELL DEATH; LAWS AND LEGISLATION; PROTEINS;

DNA;

CHECKPOINT KINASE 2; DNA; PROTEIN P53; PROTEIN P73;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; TUMOR MICROENVIRONMENT;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; DNA DAMAGE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, LEUKEMIC; GENE SILENCING; HL-60 CELLS; HUMANS; LEUKEMIA, MYELOID, ACUTE; NUCLEAR PROTEINS; PROTEIN KINASES; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; U937 CELLS;

EID: 77958452164     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.122705     Document Type: Article

References (38)

1. Green, D. R., and Kroemer, G. (2009) Nature 458, 1127-1130
2. Johnstone, R. W., Ruefli, A. A., and Lowe, S. W. (2002) Cell 108, 153-164
3. Kravchenko, J. E., Ilyinskaya, G. V., Komarov, P. G., Agapova, L. S., Kochetkov, D. V., Strom, E., Frolova, E. I., Kovriga, I., Gudkov, A. V., Feinstein, E., and Chumakov, P. M. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 6302-6307
4. Whibley, C., Pharoah, P. D., and Hollstein, M. (2009) Nat. Rev. Cancer 9, 95-107
5. Yang, A., and McKeon, F. (2000) Nat. Rev. Mol. Cell Biol. 1, 199-207
6. Johnson, R. A., Shepard, E. M., and Scotto, K. W. (2005) J. Biol. Chem. 280, 13213-13219
7. Aqeilan, R. I., Pekarsky, Y., Herrero, J. J., Palamarchuk, A., Letofsky, J., Druck, T., Trapasso, F., Han, S. Y., Melino, G., Huebner, K., and Croce, C. M. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 4401-4406
8. Grob, T. J., Fey, M. F., and Tobler, A. (2002) Cell Death Differ. 9, 229-230
9. Blint, E., Phillips, A. C., Kozlov, S., Stewart, C. L., and Vousden, K. H. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 3529-3534
10. Ra, H., Kim, H. L., Lee, H. W., and Kim, Y. H. (2009) FEBS Lett. 583, 1516-1520
11. Zhang, J., and Chen, X. (2007) Mol. Cell. Biol. 27, 3868-3880
12. Tannapfel, A., John, K., Mise, N., Schmidt, A., Buhlmann, S., Ibrahim, S. M., and Pützer, B. M. (2008) Carcinogenesis 29, 211-218
13. Ehrhardt, H., Häcker, S., Wittmann, S., Maurer, M., Borkhardt, A., Toloczko, A., Debatin, K. M., Fulda, S., and Jeremias, I. (2008) Oncogene 27, 783-793
14. Seifert, H., Mohr, B., Thiede, C., Oelschlägel, U., Schäkel, U., Illmer, T., Soucek, S. Ehninger, G., and Schaich, M. (2009) Leukemia 23, 656-663
15. Bhattacharyya, S., Mandal, D., Saha, B., Sen, G. S., Das, T., and Sa, G. (2007) J. Biol. Chem. 282, 15954-15964
16. Choudhuri, T., Pal, S., Das, T., and Sa, G. (2005) J. Biol. Chem. 280, 20059-20068
17. Sa, G., and Das, T. (2008) Cell Div. 3, 14
18. Bhattacharyya, S., Mandal, D., Sen, G. S., Pal, S., Banerjee, S., Lahiry, L., Finke, J. H., Tannenbaum, C. S., Das, T., and Sa, G. (2007) Cancer Res. 67, 362-370
19. Ng, C. P., Lee, H. C., Ho, C. W., Arooz, T., Siu, W. Y., Lau, A., and Poon, R. Y. (2004) J. Biol. Chem. 279, 8808-8819
20. Urist, M., Tanaka, T., Poyurovsky, M. V., and Prives, C. (2004) Genes Dev. 18, 3041-3054
21. Gonzalez, S., Prives, C., and Cordon-Cardo, C. (2003) Mol. Cell. Biol. 23, 8161-8171
22. Durland-Busbice, S., and Reisman, D. (2002) Leukemia 16, 2165-2167
23. Kramer, S., Ozaki, T., Miyazaki, K., Kato, C., Hanamoto, T., and Nakagawara, A. (2005) Oncogene 24, 938-944
24. Belloni, L., Moretti, F., Merlo, P., Damalas, A., Costanzo, A., Blandino, G., and Levrero, M. (2006) Oncogene 25, 3606-3612
25. Pietsch, E. C., Sykes, S. M., McMahon, S. B., and Murphy, M. E. (2008) Oncogene 27, 6507-6521
26. Flores, E. R., Sengupta, S., Miller, J. B., Newman, J. J., Bronson, R., Crowley, D., Yang, A., McKeon, F., and Jacks, T. (2005) Cancer Cell 7, 363-373
27. Hollstein, M., Hergenhahn, M., Yang, Q., Bartsch, H., Wang, Z. Q., and Hainaut, P. (1999) Mutat. Res. 431, 199-209
28. Kaelin, W. G., Jr. (1999) Oncogene 18, 7701-7705
29. Vilgelm, A., El-Rifai, W., and Zaika, A. (2008) Drug Resist. Updates 11, 152-163
30. Tse, A. N., Carvajal, R., and Schwartz, G. K. (2007) Clin. Cancer Res. 13, 1955-1960
31. Bartek, J., and Lukas, J. (2003) Cancer Cell 3, 421-429
32. Damia, G., and Broggini, M. (2004) Cell Cycle 3, 46-50
33. Damia, G., Sanchez, Y., Erba, E., and Broggini, M. (2001) J. Biol. Chem. 276, 10641-10645
34. Gottifredi, V., Karni-Schmidt, O., Shieh, S. S., and Prives, C. (2001) Mol. Cell. Biol. 21, 1066-1076
35. Nakagawa, T., Takahashi, M., Ozaki, T., Watanabe, Ki, K., Todo, S., Mizuguchi, H., Hayakawa, T., and Nakagawara, A. (2002) Mol. Cell. Biol. 22, 2575-2585
36. Zaika, A. I., Slade, N., Erster, S. H., Sansome, C., Joseph, T. W., Pearl, M., Chalas, E., and Moll, U. M. (2002) J. Exp. Med. 196, 765-780
37. Grob, T. J., Novak, U., Maisse, C., Barcaroli, D., Lüthi, A. U., Pirnia, F., Hügli, B., Graber, H. U., De Laurenzi, V., Fey, M. F., Melino, G., and Tobler, A. (2001) Cell Death Differ. 8, 1213-1223
38. Kartasheva, N. N., Contente, A., Lenz-Stöppler, C., Roth, J., and Dobbelstein, M. (2002) Oncogene 21, 4715-4727