In vivo uptake and acute immune response to orally administered chitosan and PEG coated PLGA nanoparticles

Toxicology and Applied Pharmacology

Volumn 249, Issue 2, 2010, Pages 158-165

  Semete, B ^a   Booysen, L I J ^a,b   Kalombo, L ^a   Venter, J D ^c   Katata, L ^a   Ramalapa, B ^a   Verschoor, J A ^d   Swai, H ^a  

^a Future production Chemicals Cluster   (South Africa)

^b NORTH WEST UNIVERSITY   (South Africa)

^c SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^d UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

Cytokines; Inflammation; PLGA nanoparticles

Indexed keywords

CHITOSAN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MACROGOL; MONOCYTE CHEMOTACTIC PROTEIN 1; NANOPARTICLE; POLYGLACTIN; TUMOR NECROSIS FACTOR ALPHA; ZINC OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG UPTAKE; FEMALE; IMMUNE RESPONSE; IN VIVO STUDY; MACROPHAGE; MALE; MATERIAL COATING; MOUSE; NONHUMAN; PERITONEUM LAVAGE; PROTEIN EXPRESSION;

ADMINISTRATION, ORAL; ANIMALS; CHITOSAN; CYTOKINES; DRUG DELIVERY SYSTEMS; FEMALE; LACTIC ACID; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; NANOPARTICLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID;

MUS;

EID: 77958192352     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.09.002     Document Type: Article

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