Bone status of children with hemophilia a assessed with quantitative ultrasound sonography (QUS) and dual energy X-ray absorptiometry (DXA)

Journal of Pediatric Hematology/Oncology

Volumn 32, Issue 7, 2010, Pages e259-e263

  Christoforidis, Athanasios ^a   Economou, Marina ^a   Papadopoulou, Eleni ^a   Kazantzidou, Eirini ^b   Gompakis, Nikolaos ^a   Athanassiou Metaxa, Miranda ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b Ippokration Hospital Thessaloniki   (Greece)

Author keywords

Children; Dual energy X ray absorptiometry; Hemophilia; Osteoporosis; Quantitative ultrasonography

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BONE DENSITY; CHILD; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL ASSESSMENT TOOL; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DUAL ENERGY X RAY ABSORPTIOMETRY; ECHOGRAPHY; HEMOPHILIA A; HEMOPHILIA JOINT HEALTH SCORE; HUMAN; LUMBAR SPINE; OSTEOPOROSIS; PRESCHOOL CHILD; PRIORITY JOURNAL; QUANTITATIVE ULTRASOUND SONOGRAPHY; RADIODIAGNOSIS; SCHOOL CHILD; TIBIA; ANTHROPOMETRY; LUMBAR VERTEBRA; MALE; METABOLIC BONE DISEASE; PHOTON ABSORPTIOMETRY; PREVALENCE; RADIOGRAPHY; RADIUS; RISK FACTOR;

ABSORPTIOMETRY, PHOTON; ADOLESCENT; ANTHROPOMETRY; BONE DENSITY; BONE DISEASES, METABOLIC; CHILD; CHILD, PRESCHOOL; HEMOPHILIA A; HUMANS; LUMBAR VERTEBRAE; MALE; OSTEOPOROSIS; PREVALENCE; RADIUS; RISK FACTORS; TIBIA; ULTRASONOGRAPHY;

EID: 77958156352     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e3181e8cd40     Document Type: Article

References (40)

1. Gallacher SJ, Deighan C, Wallace AM, et al. Association of severe haemophilia A with osteoporosis: a densitometric and biochemical study. Q J Med. 1994; 87: 181-186.
2. Wallny TA, Scholz DT, Oldenburg J, et al. Osteoporosis in haemophilia-an underestimated comorbidity? Haemophilia. 2007; 13: 79-84.
3. Mansouritorghabeh H, Rezaieyazdi Z, Badiei Z. Are individuals with severe haemophilia A prone to reduced bone density? Rheumatol Int. 2008; 28: 1079-1083.
4. Gerstner G, Damiano ML, Tom A, et al. Prevalence and risk factors associated with decreased bone mineral density in patients with haemophilia. Haemophilia. 2009; 15: 559-565.
5. Katsarou O, Terpos E, Chatzismalis P, et al. Increased bone resorption is implicated in the pathogenesis of bone loss in hemophiliacs: correlations with hemophilic arthropathy and HIV infection. Ann Hematol. 2010; 89: 67-74.
6. Barnes C, Wong P, Egan B, et al. Reduced bone density among children with severe hemophilia. Pediatrics. 2004; 114: e177-e181.
7. Abdelrazik N, Reda M, El-Ziny M, et al. Evaluation of bone mineral density in children with hemophilia: Mansoura University children hospital (MUCH) experience, Mansoura, Egypt. Hematology. 2007; 12: 431-437.
8. Nair AP, Jijina F, Ghosh K, et al. Osteoporosis in young haemophiliacs from western India. Am J Hematol. 2007; 82: 453-457.
9. Tlacuilo-Parra A, Morales-Zambrano R, Tostado-Rabago N, et al. Inactivity is a risk factor for low bone mineral density among haemophilic children. Br J Haematol. 2008; 140: 562-567.
10. Brown TT, Qaqish RB. Antiretroviral therapy and the prevalence of osteopenia and osteoporosis: a meta-analytic review. AIDS. 2006; 20: 2165-2174.
11. De Crignis E, Cimatti L, Borderi M, et al. Bone alterations during HIV infection. New Microbiol. 2008; 31: 155-164.
12. Lewiecki EM. Update on bone density testing. Curr Osteoporos Rep. 2005; 3: 136-142.
13. Sanchez MM, Gilsanz V. Pediatric DXA bone measurements. Pediatr Endocrinol Rev. 2005; 2(suppl 3): 337-341.
14. Specker BL, Schoenau E. Quantitative bone analysis in children: current methods and recommendations. J Pediatr. 2005; 146: 726-731.
15. Van Rijn RR, van der Sluis IM, Link TM, et al. Bone densitometry in children: a critical appraisal. Eur Radiol. 2003; 13: 700-710.
16. Gonnelli S, Cepollaro C. The use of ultrasound in the assessment of bone status. J Endocrinol Invest. 2002; 25: 389-397.
17. Hans D, Dargent-Molina P, Schott AM, et al. Ultrasonographic heel measurements to predict hip fracture in elderly women: the EPIDOS prospective study. Lancet. 1996; 348: 511-514.
18. Bauer DC, Gluer CC, Cauley JA, et al. Broadband ultrasound attenuation predicts fractures strongly and independently of densitometry in older women. A prospective study. Study of osteoporotic fractures research group. Arch Intern Med. 1997; 157: 629-634.
19. Njeh CF, Hans D, Li J, et al. Comparison of six calcaneal quantitative ultrasound devices: precision and hip fracture discrimination. Osteoporos Int. 2000; 11: 1051-1062.
20. Hartl F, Tyndall A, Kraenzlin M, et al. Discriminatory ability of quantitative ultrasound parameters and bone mineral density in a population-based sample of postmenopausal women with vertebral fractures: results of the Basel osteoporosis study. J Bone Miner Res. 2002; 17: 321-330.
21. Huopio J, Kroger H, Honkanen R, et al. Calcaneal ultrasound predicts early postmenopausal fractures as well as axial BMD. A prospective study of 422 women. Osteoporos Int. 2004; 15: 190-195.
22. Stewart A, Kumar V, Reid DM. Long-term fracture prediction by DXA and QUS: a 10-year prospective study. J Bone Miner Res. 2006; 21: 413-418.
23. Njeh CF, Fuerst T, Diessel E, et al. Is quantitative ultrasound dependent on bone structure? A reflection. Osteoporos Int. 2001; 12: 1-15.
24. Raum K, Leguerney I, Chandelier F, et al. Bone microstructure and elastic tissue properties are reflected in QUS axial transmission measurements. Ultrasound Med Biol. 2005; 31: 1225-1235.
25. Cortet B, Boutry N, Dubois P, et al. Does quantitative ultrasound of bone reflect more bone mineral density than bone microarchitecture?. Calcif Tissue Int. 2004; 74: 60-67.
26. Chiotis D, Krikos X, Tsiftis G, et al. Body mass index and prevalence of obesity in subjects of Hellenic origin aged 0-18 years, living in the Athens area. Ann Clin Pediatr Unive Atheniensis. 2004; 51: 139-154.
27. Chiotis D, Tsiftis G, Hatzisymeon M, et al. Height and weight of children of Hellenic origin aged 0-18 years (2000-2001): comparison with data collected during the period 1978-1979. Ann Clin Pediatr Unive Atheniensis. 2003; 50: 136-155.
28. Christoforidis A, Papadopoulou E, Dimitriadou M, et al. REFERENCE values for quantitative ultrasonography (QUS) of radius and tibia in healthy Greek pediatric population: clinical correlations. J Clin Densitom. 2009; 12: 360-368.
29. Hilliard P, Funk S, Zourikian N, et al. Hemophilia joint health score reliability study. Haemophilia. 2006; 12: 518-525.
30. Koch GG, Landis JR, Freeman JL, et al. A general methodology for the analysis of experiments with repeated measurement of categorical data. Biometrics. 1977; 33: 133-158.
31. Khawaji M, Akesson K, Berntorp E. Long-term prophylaxis in severe haemophilia seems to preserve bone mineral density. Haemophilia. 2009; 15: 261-266.
32. Falk B, Portal S, Tiktinsky R, et al. Anaerobic power and muscle strength in young hemophilia patients. Med Sci Sports Exerc. 2000; 32: 52-57.
33. Falk B, Portal S, Tiktinsky R, et al. Bone properties and muscle strength of young haemophilia patients. Haemophilia. 2005; 11: 380-386.
34. Tiktinsky R, Falk B, Heim M, et al. The effect of resistance training on the frequency of bleeding in haemophilia patients: a pilot study. Haemophilia. 2002; 8: 22-27.
35. Gregg EW, Kriska AM, Salamone LM, et al. The epidemiology of quantitative ultrasound: a review of the relationships with bone mass, osteoporosis and fracture risk. Osteoporos Int. 1997; 7: 89-99.
36. Schwartz DA, Connolley CD, Koyama T, et al. Calcaneal ultrasound bone densitometry is not a useful tool to screen patients with inflammatory bowel disease at high risk for metabolic bone disease. Inflamm Bowel Dis. 2005; 11: 749-754.
37. Rossini M, Viapiana O, Del Marco A, et al. Quantitative ultrasound in adults with cystic fibrosis: correlation with bone mineral density and risk of vertebral fractures. Calcif Tissue Int. 2007; 80: 44-49.
38. Oswiecimska J, Ziora K, Pluskiewicz W, et al. Skeletal status and laboratory investigations in adolescent girls with anorexia nervosa. Bone. 2007; 41: 103-110.
39. Christoforidis A, Perifanis V, Papadopoulou E, et al. Poor correlations between measurements of bone quality by quantitative ultrasound sonography and dual energy x-ray absorptiometry in patients with beta-thalassaemia major. Eur J Haematol. 2009; 82: 15-21.
40. Jenson F, Padilla F, Bousson V, et al. In vitro ultrasonic characterization of human cancellous femoral bone using transmission and backscatter measurements: relationships to bone mineral density. J Acoust Soc Am. 2006; 119: 654-663.