Analysis of in vitro drug dissolution from PCL melt extrusion

Chemical Engineering Journal

Volumn 164, Issue 2-3, 2010, Pages 359-370

  Douglas, P ^a   Andrews, G ^a   Jones, D ^a   Walker, G ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Drug dissolution; Drug release kinetics; Melt extrusion; Polycaprolactone

Indexed keywords

AMORPHOUS REGIONS; AQUEOUS CONDITION; BULK DIFFUSIONS; CONTROLLED COOLING; COOLING RATES; DEGRADATION RATE; DIFFUSION COEFFICIENTS; DRUG DELIVERY SYSTEM; DRUG DISSOLUTION; DRUG RELEASE; DRUG RELEASE KINETICS; EXPERIMENTAL DATA; EXPERIMENTAL KINETICS; EXTERNAL ENVIRONMENTS; EXTRUDATES; EXTRUSION PROCESS; HIGHER-DEGREE; HYDROLYTIC DEGRADATION; IN-VITRO; MASS TRANSPORT; MATRIX; MATRIX STRUCTURE; MELT EXTRUSION; NALIDIXIC ACID; PEPPAS MODEL; PLLA; POLYMER CRYSTALS; PORE FORMERS; SIMPLE APPROACH; THREE COMPONENT; TWIN SCREW EXTRUSION;

ACIDS; COOLING; DEGRADATION; DISSOLUTION; DRUG DELIVERY; DRUG PRODUCTS; MATRIX ALGEBRA; MELT SPINNING; POLYCAPROLACTONE; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMER BLENDS; SOLUBILITY; TRANSPORTATION;

EXTRUSION;

EID: 77958150715     PISSN: 13858947     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cej.2010.03.077     Document Type: Article

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