Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10

Biochemical and Biophysical Research Communications

Volumn 401, Issue 3, 2010, Pages 412-416

  Kim, Joanna ^a   Shin, Sook ^b   Subramaniam, Malayannan ^a   Bruinsma, Elizabeth ^a   Kim, Tae Dong ^b   Hawse, John R ^a   Spelsberg, Thomas C ^a   Janknecht, Ralf ^b  

^a MAYO GRADUATE SCHOOL   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Cancer; Corepressor; Histone demethylase; Kr ppel like transcription factor; Smad7; Transforming growth factor

Indexed keywords

HISTONE H3; JUMONJI AT RICH INTERACTIVE DOMAIN 1B; KRUPPEL LIKE FACTOR 10; LYSINE SPECIFIC DEMETHYLASE 5B; OSTEOPROTEGERIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA INDUCIBLE EARLY GENE 1 PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ARTICLE; BONE METABOLISM; BREAST CANCER; CANCER INHIBITION; CARCINOGENESIS; CELL STRAIN; CELL STRAIN HEK293; CELL STRAIN MDA MB 231; CHROMATIN; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MELANOMA; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

CELL LINE; EARLY GROWTH RESPONSE TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; REPRESSOR PROTEINS; TRANSCRIPTION, GENETIC;

EID: 77958150187     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.09.068     Document Type: Article

References (38)

1. Yamane K., Tateishi K., Klose R.J., Fang J., Fabrizio L.A., Erdjument-Bromage H., Taylor-Papadimitriou J., Tempst P., Zhang Y. PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. Mol. Cell 2007, 25:801-812.
2. Christensen J., Agger K., Cloos P.A., Pasini D., Rose S., Sennels L., Rappsilber J., Hansen K.H., Salcini A.E., Helin K. RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3. Cell 2007, 128:1063-1076.
3. Seward D.J., Cubberley G., Kim S., Schonewald M., Zhang L., Tripet B., Bentley D.L. Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins. Nat. Struct. Mol. Biol. 2007, 14:240-242.
4. Xiang Y., Zhu Z., Han G., Ye X., Xu B., Peng Z., Ma Y., Yu Y., Lin H., Chen A.P., Chen C.D. JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:19226-19231.
5. Martin C., Zhang Y. The diverse functions of histone lysine methylation. Nat. Rev. Mol. Cell Biol. 2005, 6:838-849.
6. Tan K., Shaw A.L., Madsen B., Jensen K., Taylor-Papadimitriou J., Freemont P.S. Human PLU-1 has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9. J. Biol. Chem. 2003, 278:20507-20513.
7. Scibetta A.G., Santangelo S., Coleman J., Hall D., Chaplin T., Copier J., Catchpole S., Burchell J., Taylor-Papadimitriou J. Functional analysis of the transcription repressor PLU-1/JARID1B. Mol. Cell Biol. 2007, 27:7220-7235.
8. Lu P.J., Sundquist K., Baeckstrom D., Poulsom R., Hanby A., Meier-Ewert S., Jones T., Mitchell M., Pitha-Rowe P., Freemont P., Taylor-Papadimitriou J. A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer. J. Biol. Chem. 1999, 274:15633-15645.
9. Barrett A., Madsen B., Copier J., Lu P.J., Cooper L., Scibetta A.G., Burchell J., Taylor-Papadimitriou J. PLU-1 nuclear protein, which is upregulated in breast cancer, shows restricted expression in normal human adult tissues: a new cancer/testis antigen?. Int. J. Cancer 2002, 101:581-588.
10. Hayami S., Yoshimatsu M., Veerakumarasivam A., Unoki M., Iwai Y., Tsunoda T., Field H.I., Kelly J.D., Neal D.E., Yamaue H., Ponder B.A., Nakamura Y., Hamamoto R. Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway. Mol. Cancer 2010, 9:59.
11. Roesch A., Becker B., Meyer S., Wild P., Hafner C., Landthaler M., Vogt T. Retinoblastoma-binding protein 2-homolog 1: a retinoblastoma-binding protein downregulated in malignant melanomas. Mod. Pathol. 2005, 18:1249-1257.
12. Roesch A., Becker B., Schneider-Brachert W., Hagen I., Landthaler M., Vogt T. Re-expression of the retinoblastoma-binding protein 2-homolog 1 reveals tumor-suppressive functions in highly metastatic melanoma cells. J. Invest. Dermatol. 2006, 126:1850-1859.
13. Subramaniam M., Hawse J.R., Johnsen S.A., Spelsberg T.C. Role of TIEG1 in biological processes and disease states. J. Cell. Biochem. 2007, 102:539-548.
14. Subramaniam M., Hefferan T.E., Tau K., Peus D., Pittelkow M., Jalal S., Riggs B.L., Roche P., Spelsberg T.C. Tissue, cell type, and breast cancer stage-specific expression of a TGF-beta inducible early transcription factor gene. J. Cell. Biochem. 1998, 68:226-236.
15. Reinholz M.M., An M.W., Johnsen S.A., Subramaniam M., Suman V.J., Ingle J.N., Roche P.C., Spelsberg T.C. Differential gene expression of TGF beta inducible early gene (TIEG), Smad7, Smad2 and Bard1 in normal and malignant breast tissue. Breast Cancer Res. Treat. 2004, 86:75-88.
16. Massague J. TGFbeta in Cancer. Cell 2008, 134:215-230.
17. Johnsen S.A., Subramaniam M., Janknecht R., Spelsberg T.C. TGFbeta inducible early gene enhances TGFbeta/Smad-dependent transcriptional responses. Oncogene 2002, 21:5783-5790.
18. Johnsen S.A., Subramaniam M., Katagiri T., Janknecht R., Spelsberg T.C. Transcriptional regulation of Smad2 is required for enhancement of TGFbeta/Smad signaling by TGFbeta inducible early gene. J. Cell. Biochem. 2002, 87:233-241.
19. Dowdy S.C., Mariani A., Janknecht R. HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81. J. Biol. Chem. 2003, 278:44377-44384.
20. Shin S., Janknecht R. Diversity within the JMJD2 histone demethylase family. Biochem. Biophys. Res. Commun. 2007, 353:973-977.
21. Shin S., Janknecht R. Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D. Biochem. Biophys. Res. Commun. 2007, 359:742-746.
22. Kim T.D., Shin S., Janknecht R. Repression of Smad3 activity by histone demethylase SMCX/JARID1C. Biochem. Biophys. Res. Commun. 2008, 366:563-567.
23. Janknecht R. Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1). Oncogene 2003, 22:746-755.
24. Goel A., Janknecht R. Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu. J. Biol. Chem. 2004, 279:14909-14916.
25. Wu J., Janknecht R. Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A. J. Biol. Chem. 2002, 277:42669-42679.
26. Knebel J., De Haro L., Janknecht R. Repression of transcription by TSGA/Jmjd1a, a novel interaction partner of the ETS protein ER71. J. Cell. Biochem. 2006, 99:319-329.
27. Papoutsopoulou S., Janknecht R. Phosphorylation of ETS transcription factor ER81 in a complex with its coactivators CREB-binding protein and p300. Mol. Cell. Biol. 2000, 20:7300-7310.
28. Goueli B.S., Janknecht R. Upregulation of the catalytic telomerase subunit by the transcription factor ER81 and oncogenic HER2/Neu, Ras, or Raf. Mol. Cell. Biol. 2004, 24:25-35.
29. Shin S., Janknecht R. Concerted activation of the Mdm2 promoter by p72 RNA helicase and the coactivators p300 and P/CAF. J. Cell. Biochem. 2007, 101:1252-1265.
30. Shin S., Kim T.D., Jin F., van Deursen J.M., Dehm S.M., Tindall D.J., Grande J.P., Munz J.M., Vasmatzis G., Janknecht R. Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81. Cancer Res. 2009, 69:8102-8110.
31. Goel A., Janknecht R. Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu. Mol. Cell. Biol. 2003, 23:6243-6254.
32. Shin S., Bosc D.G., Ingle J.N., Spelsberg T.C., Janknecht R. Rcl is a novel ETV1/ER81 target gene upregulated in breast tumors. J. Cell. Biochem. 2008, 105:866-874.
33. Shin S., Rossow K.L., Grande J.P., Janknecht R. Involvement of RNA helicases p68 and p72 in colon cancer. Cancer Res. 2007, 67:7572-7578.
34. Subramaniam M., Hawse J.R., Bruinsma E.S., Grygo S.B., Cicek M., Oursler M.J., Spelsberg T.C. TGFbeta inducible early gene-1 directly binds to, and represses, the OPG promoter in osteoblasts. Biochem. Biophys. Res. Commun. 2010, 392:72-76.
35. Venuprasad K., Huang H., Harada Y., Elly C., Subramaniam M., Spelsberg T., Su J., Liu Y.C. The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1. Nat. Immunol. 2008, 9:245-253.
36. Cao Z., Wara A.K., Icli B., Sun X., Packard R.R., Esen F., Stapleton C.J., Subramaniam M., Kretschmer K., Apostolou I., von Boehmer H., Hansson G.K., Spelsberg T.C., Libby P., Feinberg M.W. Kruppel-like factor KLF10 targets transforming growth factor-beta1 to regulate CD4(+)CD25(-) T cells and T regulatory cells. J. Biol. Chem. 2009, 284:24914-24924.
37. Guillaumond F., Grechez-Cassiau A., Subramaniam M., Brangolo S., Peteri-Brunback B., Staels B., Fievet C., Spelsberg T.C., Delaunay F., Teboul M. Kruppel-like factor KLF10 is a link between the circadian clock and metabolism in liver. Mol. Cell. Biol. 2010, 30:3059-3070.
38. Talantov D., Mazumder A., Yu J.X., Briggs T., Jiang Y., Backus J., Atkins D., Wang Y. Novel genes associated with malignant melanoma but not benign melanocytic lesions. Clin. Cancer Res. 2005, 11:7234-7242.