Preventive effects of Flos Perariae (Gehua) water extract and its active ingredient puerarin in rodent alcoholism models

Chinese Medicine

Volumn 5, Issue , 2010, Pages

  Zhang, Zaijun ^a   Li, Sha ^a   Jiang, Jie ^a   Yu, Pei ^a   Liang, Jing ^b   Wang, Yuqiang ^a  

^a JINAN UNIVERSITY   (China)

^b UCLA SCHOOL OF DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ALCOHOL DEHYDROGENASE; DIAZEPAM; FLOS PUERARIAE EXTRACT; PLANT EXTRACT; PUERARIN; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; HIPPOCAMPUS; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; RIGHTING REFLEX; WEIGHT GAIN; WESTERN BLOTTING;

EID: 77958138748     PISSN: None     EISSN: 17498546     Source Type: Journal    
DOI: 10.1186/1749-8546-5-36     Document Type: Article

References (39)

1. Bayard M, McIntyre J, Hill KR, Woodside J. Alcohol withdrawal syndrome. Am Fam Physician 2004, 69:1443-1450.
2. Trevisan LA, Boutros N, Petrakis IL, Krystal JH. Complications of alcohol withdrawal: pathophysiological insights. Alcohol Health Res World 1998, 22:61-66.
3. Brower KJ, Aldrich MS, Robinson EA, Zucker RA, Greden JF. Insomnia, self-medication, and relapse to alcoholism. Am J Psychiatry 2001, 158:399-404. 10.1176/appi.ajp.158.3.399, 11229980.
4. Booth BM, Blow FC. The kindling hypothesis: further evidence from a U.S. national study of alcoholic men. Alcohol Alcohol 1993, 28:593-598.
5. Becker HC, Hale RL. Repeated episodes of ethanol withdrawal potentiate the severity of subsequent withdrawal seizures: an animal model of alcohol withdrawal "kindling". Alcohol Clin Exp Res 1993, 17:94-98. 10.1111/j.1530-0277.1993.tb00731.x, 8452212.
6. Veatch LM, Gonzalez LP. Repeated ethanol withdrawal produces site-dependent increases in EEG spiking. Alcohol Clin Exp Res 1996, 20:262-267. 10.1111/j.1530-0277.1996.tb01638.x, 8730216.
7. Haranaka R, Okada N, Kosoto H, Ohwada S, Hasegawa R, Nakagawa S, Kobayashi M. Effects of wu-ling-san on alcohol metabolism and alcoholic liver. J Tradit Chin Med 1985, 5:171-178.
8. Xu BJ, Zheng YN, Sung CK. Natural medicines for alcoholism treatment: a review. Drug Alcohol Rev 2005, 24:525-536. 10.1080/09595230500293795, 16361209.
9. Keung WM, Vallee BL. Kudzu root: an ancient Chinese source of modern antidipsotropic agents. Phytochemistry 1998, 47:499-506. 10.1016/S0031-9422(97)00723-1, 9461670.
10. Lukas SE, Penetar D, Berko J, Vicens L, Palmer C, Mallya G, Macklin EA, Lee DY. An extract of the Chinese herbal root kudzu reduces alcohol drinking by heavy drinkers in a naturalistic setting. Alcohol Clin Exp Res 2005, 29:756-762. 10.1097/01.ALC.0000163499.64347.92, 15897719.
11. Overstreet DH, Keung WM, Rezvani AH, Massi M, Lee DY. Herbal remedies for alcoholism: promises and possible pitfalls. Alcohol Clin Exp Res 2003, 27:177-185. 10.1097/01.ALC.0000051022.26489.CF, 12605067.
12. Heyman GM, Keung WM, Vallee BL. Daidzin decreases ethanol consumption in rats. Alcohol Clin Exp Res 1996, 20:1083-1087. 10.1111/j.1530-0277.1996.tb01950.x, 8892531.
13. Rooke N, Li DJ, Li J, Keung WM. The mitochondrial monoamine oxidase-aldehyde dehydrogenase pathway: a potential site of action of daidzin. J Med Chem 2000, 43:4169-4179. 10.1021/jm990614i, 11063613.
14. Benlhabib E, Baker JI, Keyler DE, Singh AK. Kudzu root extract suppresses voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol. J Med Food 2004, 7:168-179. 10.1089/1096620041224210, 15298764.
15. Ariwodola OJ, Crowder TL, Grant KA, Daunais JB, Friedman DP, Weiner JL. Ethanol modulation of excitatory and inhibitory synaptic transmission in rat and monkey dentate granule neurons. Alcohol Clin Exp Res 2003, 27:1632-1639. 10.1097/01.ALC.0000089956.43262.17, 14574234.
16. Aroor AR, Shukla SD. MAP kinase signaling in diverse effects of ethanol. Life Sci 2004, 74:2339-2364. 10.1016/j.lfs.2003.11.001, 15027449.
17. Cagetti E, Liang J, Spigelman I, Olsen RW. Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors. Mol Pharmacol 2003, 63:53-64. 10.1124/mol.63.1.53, 12488536.
18. Liang J, Cagetti E, Olsen RW, Spigelman I. Altered pharmacology of synaptic and extrasynaptic GABAA receptors on CA1 hippocampal neurons is consistent with subunit changes in a model of alcohol withdrawal and dependence. J Pharmacol Exp Ther 2004, 310:1234-1245. 10.1124/jpet.104.067983, 15126642.
19. Liang J, Zhang N, Cagetti E, Houser CR, Olsen RW, Spigelman I. Chronic intermittent ethanol-induced switch of ethanol actions from extrasynaptic to synaptic hippocampal GABAA receptors. J Neurosci 2006, 26:1749-1758. 10.1523/JNEUROSCI.4702-05.2006, 16467523.
20. Edenberg HJ, Xuei X, Chen HJ, Tian H, Wetherill LF, Dick DM, Almasy L, Bierut L, Bucholz KK, Goate A, et al. Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. Hum Mol Genet 2006, 15:1539-1549. 10.1093/hmg/ddl073, 16571603.
21. Institute of Materia Medica CAoMS Zhong Yao Zhi 1995, Beijing, Institute of Materia Medica CAoMS.
22. Boehm SL, Ponomarev I, Jennings AW, Whiting PJ, Rosahl TW, Garrett EM, Blednov YA, Harris RA. gamma-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions. Biochem Pharmacol 2004, 68:1581-1602. 10.1016/j.bcp.2004.07.023, 15451402.
23. Liang J, Suryanarayanan A, Abriam A, Snyder B, Olsen RW, Spigelman I. Mechanisms of reversible GABAA receptor plasticity after ethanol intoxication. J Neurosci 2007, 27:12367-12377. 10.1523/JNEUROSCI.2786-07.2007, 17989301.
24. Liang JH, Chen F, Krstew E, Cowen MS, Carroll FY, Crawford D, Beart PM, Lawrence AJ. The GABA(B) receptor allosteric modulator CGP7930, like baclofen, reduces operant self-administration of ethanol in alcohol-preferring rats. Neuropharmacology 2006, 50:632-639. 10.1016/j.neuropharm.2005.11.011, 16406445.
25. McGregor NR. Pueraria lobata (Kudzu root) hangover remedies and acetaldehyde-associated neoplasm risk. Alcohol 2007, 41:469-478. 10.1016/j.alcohol.2007.07.009, 17980785.
26. Zhang JF, Lu YX, Qiu XX, Fang Y. Relationship between alcohol drinking and alcohol-related health problems. Biomed Environ Sci 2004, 17:196-202.
27. Lin RC, Li TK. Effects of isoflavones on alcohol pharmacokinetics and alcohol-drinking behavior in rats. Am J Clin Nutr 1998, 68:1512S-1515S.
28. Overstreet DH, Lee YW, Rezvani AH, Pei YH, Criswell HE, Janowsky DS. Suppression of alcohol intake after administration of the Chinese herbal medicine, NPI-028, and its derivatives. Alcohol Clin Exp Res 1996, 20:221-227. 10.1111/j.1530-0277.1996.tb01633.x, 8730211.
29. Keung WM, Vallee BL. Daidzin: a potent, selective inhibitor of human mitochondrial aldehyde dehydrogenase. Proc Natl Acad Sci USA 1993, 90:1247-1251. 10.1073/pnas.90.4.1247, 45849, 8433985.
30. Keung WM. Biochemical studies of a new class of alcohol dehydrogenase inhibitors from Radix puerariae. Alcohol Clin Exp Res 1993, 17:1254-1260. 10.1111/j.1530-0277.1993.tb05238.x, 8116840.
31. Keung WM, Lazo O, Kunze L, Vallee BL. Daidzin suppresses ethanol consumption by Syrian golden hamsters without blocking acetaldehyde metabolism. Proc Natl Acad Sci USA 1995, 92:8990-8993. 10.1073/pnas.92.19.8990, 41093, 7568058.
32. Fernandez-Sola J, Preedy VR, Lang CH, Gonzalez-Reimers E, Arno M, Lin JC, Wiseman H, Zhou S, Emery PW, Nakahara T, et al. Molecular and cellular events in alcohol-induced muscle disease. Alcohol Clin Exp Res 2007, 31:1953-1962. 10.1111/j.1530-0277.2007.00530.x, 18034690.
33. Singal AK, Anand BS. Mechanisms of synergy between alcohol and hepatitis C virus. J Clin Gastroenterol 2007, 41:761-772. 10.1097/MCG.0b013e3180381584, 17700425.
34. Song BJ, Moon KH, Olsson NU, Salem N. Prevention of alcoholic fatty liver and mitochondrial dysfunction in the rat by long-chain polyunsaturated fatty acids. J Hepatol 2008, 49:262-273. 10.1016/j.jhep.2008.04.023, 2532851, 18571270.
35. Sancho-Tello M, Muriach M, Barcia J, Bosch-Morell F, Genoves JM, Johnsen-Soriano S, Romero B, Almansa I, Diaz-Llopis M, Garcia-Delpech S, et al. Chronic alcohol feeding induces biochemical, histological, and functional alterations in rat retina. Alcohol Alcohol 2008, 43:254-260.
36. Warnakulasuriya S, Parkkila S, Nagao T, Preedy VR, Pasanen M, Koivisto H, Niemela O. Demonstration of ethanol-induced protein adducts in oral leukoplakia (pre-cancer) and cancer. J Oral Pathol Med 2008, 37:157-165. 10.1111/j.1600-0714.2007.00605.x, 18251940.
37. Li Y, Walker DW, King MA. Peroxide mediates ethanol-induced cytotoxicity in PC12 cells. Free Radic Biol Med 2001, 30:389-392. 10.1016/S0891-5849(00)00484-6, 11182294.
38. Lockhart B, Jones C, Cuisinier C, Villain N, Peyroulan D, Lestage P. Inhibition of L-homocysteic acid and buthionine sulphoximine-mediated neurotoxicity in rat embryonic neuronal cultures with alpha-lipoic acid enantiomers. Brain Res 2000, 855:292-297. 10.1016/S0006-8993(99)02372-0, 10677603.
39. Cao X, Tian Y, Zhang T, Li X, Ito Y. Separation and purification of isoflavones from Pueraria lobata by high-speed counter-current chromatography. J Chromatogr A 1999, 855:709-713. 10.1016/S0021-9673(99)00715-3, 10519106.