Perturbation of adhesion molecule-mediated chondrocyte-matrix interactions by 4-hydroxynonenal binding: Implication in osteoarthritis pathogenesis

Arthritis Research and Therapy

Volumn 12, Issue 5, 2010, Pages

  El Bikai, Rana ^a   Welman, Mélanie ^a   Margaron, Yoran ^a   Côté, Jean François ^a   Macqueen, Luke ^a   Buschmann, Michael D ^a   Fahmi, Hassan ^a   Shi, Qin ^a   Maghni, Karim ^a   Fernandes, Julio C ^a   Benderdour, Mohamed ^a  

^a HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; CARNOSINE; CASPASE; CELL ADHESION MOLECULE; COLLAGEN TYPE 2; COLLAGENASE 3; CYCLOOXYGENASE 2; FOCAL ADHESION KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN E2; SYNAPTOTAGMIN I; VERY LATE ACTIVATION ANTIGEN 1; 4-HYDROXY-2-NONENAL; ALDEHYDE; MESSENGER RNA;

ARTICLE; CARTILAGE CELL; CELL ADHESION; CELL DEATH; CELL STRUCTURE; CELL VIABILITY; CONFOCAL MICROSCOPY; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; OSTEOARTHRITIS; PATHOGENESIS; PHASE CONTRAST MICROSCOPE; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; AGED; CELL CULTURE; CELL SEPARATION; DRUG EFFECT; EXTRACELLULAR MATRIX; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

AGED; ALDEHYDES; BLOTTING, WESTERN; CARNOSINE; CELL ADHESION MOLECULES; CELL SEPARATION; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOPRECIPITATION; MICROSCOPY, CONFOCAL; OSTEOARTHRITIS; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 77958127588     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar3173     Document Type: Article

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