The role of prefrontal cortex in predictive fear learning

Behavioral Neuroscience

Volumn 124, Issue 5, 2010, Pages 574-586

  Furlong, Teri M ^a   Cole, Sindy ^a   Hamlin, Adam S ^a   McNally, Gavan P ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Anterior cingulate; Orbitofrontal cortex; Prediction error; Prefrontal cortex; Thalamus

Indexed keywords

PROTEIN C FOS;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CONDITIONING; CONTROLLED STUDY; EPITHALAMUS; FEAR; HYPOTHALAMUS NUCLEUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LEARNING; MALE; MESENCEPHALON; NERVE TRACT; NONHUMAN; PREFRONTAL CORTEX; RAT; THALAMOCORTICAL TRACT; VENTRAL TEGMENTUM;

AMYGDALA; ANIMALS; CONDITIONING, CLASSICAL; FEAR; INHIBITION (PSYCHOLOGY); MALE; NEURAL PATHWAYS; NEUROANATOMICAL TRACT-TRACING TECHNIQUES; PREFRONTAL CORTEX; RATS; RATS, WISTAR; THALAMUS;

EID: 77958123109     PISSN: 07357044     EISSN: 19390084     Source Type: Journal    
DOI: 10.1037/a0020739     Document Type: Article

References (42)

1. Berendse H.W., Groenewegen H.J. Restricted cortical termination fields of the midline and intralaminar thalamic nuclei in the rat. Neuroscience 1991, 42:73-102.
2. Brunzell D.H., Kim J.J. Fear conditioning to tone, but not context, is attenuated by lesions of the insular cortex and posterior extension of the intralaminar complex in rats. Behavioral Neuroscience 2001, 115:365-375.
3. Burgos-Robles A., Vidal-Gonzalez I., Quirk G.J. Sustained conditioned responses in prelimbic prefrontal neurons are correlated with fear expression and extinction failure. The Journal of Neuroscience 2009, 29:8474-8482.
4. Carter C.S., van Veen V. Anterior cingulate cortex and conflict detection: An update of theory and data. Cognitive Affective and Behavioral Neuroscience 2007, 7:367-379.
5. Cole S., McNally G.P. Opioid receptors mediate direct predictive fear learning: Evidence from one-trial blocking. Learning & Memory 2007, 14:229-235.
6. Cole S., McNally G.P. Complementary roles for amygdala and periaqueductal gray in temporal-difference fear learning. Learning & Memory 2009, 16:1-7.
7. Corcoran K.A., Quirk G.J. Activity in prelimbic cortex is necessary for the expression of learned, but not innate, fears. The Journal of Neuroscience 2007, 27:840-844.
8. Dunsmoor J.E., Bandettini P.A., Knight D.C. Neural correlates of unconditioned response diminution during Pavlovian conditioning. Neuroimage 2008, 40:811-817.
9. Fanselow M.S. Pavlovian conditioning, negative feedback, and blocking: Mechanisms that regulate association formation. Neuron 1998, 20:625-627.
10. Groenewegen H.J., Berendse H.W. The specificity of the "nonspecific" midline and intralaminar thalamic nuclei. Trends in Neuroscience 1994, 17:52-57.
11. Histed M.H., Pasupathy A., Miller E.K. Learning substrates in the primate prefrontal cortex and striatum: Sustained activity related to successful actions. Neuron 2009, 63:244-253.
12. Holschneider D.P., Yang J., Sadler T.R., Nguyen P.T., Givrad T.K., Maarek J.M. Mapping cerebral blood flow changes during auditory-cued conditioned fear in the nontethered, nonrestrained rat. Neuroimage 2006, 29:1344-1358.
13. Iordanova M.D., McNally G.P., Westbrook R.F. Opioid receptors in the nucleus accumbens regulate attentional learning in the blocking paradigm. The Journal of Neuroscience 2006, 26:4036-4045.
14. Jasmin L., Burkey A.R., Granato A., Ohara P.T. Rostral agranular insular cortex and pain areas of the central nervous system: A tract-tracing study in the rat. The Journal of Comparative Neurology 2004, 468:425-440.
15. Johansen J.P., Fields H.L. Glutamatergic activation of anterior cingulate cortex produces an aversive teaching signal. Nature Neuroscience 2004, 7:398-403.
16. Kamin, L. J. (1968). "Attention-like" processes in classical conditioning. In M. R. Jones (Ed.), Miami symposium on the prediction of behavior: Aversive stimulation (pp. 9-33). University of Miami: Miami:.
17. Kim J.J., Jung M.W. Neural circuits and mechanisms involved in Pavlovian fear conditioning: A critical review. Neuroscience and Biobehavioral Reviews 2006, 30:188-202.
18. Krout K.E., Loewy A.D. Periaqueductal gray matter projections to midline and intralaminar thalamic nuclei of the rat. The Journal of Comparative Neurology 2000, 424:111-141.
19. Lacroix L., Spinelli S., Heidbreder C.A., Feldon J. Differential role of the medial and lateral prefrontal cortices in fear and anxiety. Behavioral Neuroscience 2000, 114:1119-1130.
20. Lanuza E., Nader K., LeDoux J.E. Unconditioned stimulus pathways to the amygdala: Effects of posterior thalamic and cortical lesions on fear conditioning. Neuroscience 2004, 125:305-315.
21. Laurent V., Westbrook R.F. Inactivation of the infralimbic but not the prelimbic cortex impairs consolidation and retrieval of fear extinction. Learning & Memory 2009, 16:520-529.
22. Maren S., Quirk G.J. Neuronal signalling of fear memory. Nature Reviews Neuroscience 2004, 5:844-852.
23. Matsumoto M., Matsumoto K., Abe H., Tanaka K. Medial prefrontal cell activity signaling prediction errors of action values. Nature Neuroscience 2007, 10:647-656.
24. McLaren I.P.L. The computational unit as an assembly of neurones: An implementation of an error correcting learning algorithm. The computing neuron 1989, 160-179. Addison Wesley, Amsterdam. R. Durbin, C. Miall, G. Mitchison (Eds.).
25. McNally G.P. The roles of endogenous opioids in fear learning. International Journal of Comparative Psychology 2009, 22:153-169.
26. McNally G.P., Cole S. Opioid receptors in the midbrain periaqueductal gray regulate prediction errors during Pavlovian fear conditioning. Behavioral Neuroscience 2006, 121:313-323.
27. McNally G.P., Pigg M., Weidemann G. Blocking, unblocking and overexpectation of fear: Opioid receptors regulate Pavlovian association formation. Behavioral Neuroscience 2004, 118:111-120.
28. McNally G.P., Westbrook R.F. Predicting danger: The nature, consequences, and neural mechanisms of predictive fear learning. Learning & Memory 2006, 13:245-253.
29. Milad M.R., Vidal-Gonzalez I., Quirk G.J. Electrical stimulation of medial prefrontal cortex reduces conditioned fear in a temporally specific manner. Behavioral Neuroscience 2004, 118:389-394.
30. Miller E.K., Cohen J.D. An integrative theory of prefrontal cortex function. Annual Review of Neuroscience 2001, 24:167-202.
31. Morgan M.A., LeDoux J.E. Differential contribution of dorsal and ventral medial prefrontal cortex to the acquisition and extinction of conditioned fear in rats. Behavioral Neuroscience 1995, 109:681-688.
32. Narayanan N.S., Laubach M. Neuronal correlates of post-error slowing in the rat dorsomedial prefrontal cortex. Journal of Neurophysiology 2008, 100:520-525.
33. O'Brien R.G., Kaiser M.K. MANOVA method for analysing repeated measures designs: An extensive primer. Psychological Bulletin 1985, 97:316-333.
34. Paxinos G., Watson C. The rat brain in stereotaxic coordinates 2005, Elsevier, San Diego. 5th ed.
35. Paxinos G., Watson C. The rat brain in stereotaxic coordinates 2007, Elsevier, San Diego. 6th ed.
36. Price D.D. Psychological and neural mechanisms of the affective dimension of pain. Science 2000, 288:1769-1772.
37. Rescorla R.A., Wagner A.R. A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and nonreinforcement. Classical conditioning II: Current research and theory 1972, 64-99. Appleton-Century-Crofts, New York. A.H. Black, W.F. Prokasy (Eds.).
38. Santini E., Quirk G.J., Porter J.T. Fear conditioning and extinction differentially modify the intrinsic excitability of infralimbic neurons. The Journal of Neuroscience 2008, 28:4028-4036.
39. Shi C., Davis M. Pain pathways involved in fear conditioning measured with fear-potentiated startle: Lesion studies. The Journal of Neuroscience 1999, 19:420-430.
40. Takahashi Y.K., Roesch M.R., Stalnaker T.A., Haney R.Z., Calu D.J., Taylor A.R., Burke K.A., et al. The orbitofrontal cortex and ventral tegmental area are necessary for learning from unexpected outcomes. Neuron 2009, 62:269-280.
41. Taylor S.F., Stern E.R., Gehring W.J. Neural systems for error monitoring: Recent findings and theoretical perspectives. Neuroscientist 2007, 13:160-172.
42. Vidal-Gonzalez I., Vidal-Gonzalez B., Rauch S.L., Quirk G.J. Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear. Learning & Memory 2006, 13:728-733.