Differential role of the medial and lateral prefrontal cortices in fear and anxiety

Behavioral Neuroscience

Volumn 114, Issue 6, 2000, Pages 1119-1130

  Lacroix, Laurent ^a   Spinelli, Simona ^a   Heidbreder, Christian A ^a   Feldon, Joram ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; ASSOCIATION; BRAIN FUNCTION; BRAIN INJURY; CONDITIONING; FEAR; FREEZING; LIMBIC CORTEX; MALE; MAZE TEST; NONHUMAN; OPEN FIELD BEHAVIOR; PREFRONTAL CORTEX; RAT;

EID: 0034538705     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.114.6.1119     Document Type: Article

References (69)

1. Effects on respiration, blood pressure and gastric motility of stimulation of orbital surface of frontal lobe
2. Innate and conditioned reactions to threat in rats with amygdaloid lesions
3. Effects of ibotenic acid lesion of the medial prefrontal cortex on dopamine agonist-related behaviors in the rat
4. Effects of lesions to amygdala, ventral subiculum, medial prefrontal cortex, and nucleus accumbens on the reaction to novelty: Implication for limbi-striatal interactions
5. Neuropeptide changes following excitotoxic lesion of the insular cortex in rats
6. Pharmacological and anatomical analysis of fear conditioning
7. The role of the amygdala in fear-potentiated startle: Implications for animal models of anxiety
8. Use of the elevated plus maze in the search for novel anxiolytic agents
9. Social behaviour and the prefrontal cortex
10. Behavioural changes following lesions of the orbital prefrontal cortex in male rats
11. The role of the medial prefrontal cortex (cingulate gyms) in the regulation of hypothalamicpituitary-adrenal responses to stress
12. Anatomical and electrophysiological evidence for a direct projection from Ammon's horn to the medial prefrontal cortex
13. Medial prefrontal lesion deficits involving or sparing the prelimbic area in the rat
14. The effect of medial frontal cortex lesions on respiration, 'freezing', and ultrasonic vocalizations during conditioned emotional responses in rats
15. Normal conditioned inhibition and extinction of freezing and fear-potentiated startle following electrolytic lesions of medial prefrontal cortex in rats
16. Comparison between the behavioural effects of septal and hippocampal lesions: A review
17. Contrasting effects of centromedial and basolateral amygdaloid lesions on stress-related responses in the rat
18. The anatomical relationship of the prefrontal cortex with the striatopallidal system, the thalamus and the amygdala: Evidence for a parallel organization
19. Orbital cortical influences on cardiovascular dynamics and myocardial structure in conscious monkeys
20. Prefrontal stimulus-produced hypotension in rat
21. Effects of cocaine on dopamine in subregions of the rat prefrontal cortex and their efferents to subterritories of the nucleus accumbens
22. Amphetamine microinfusion in the dorso-ventral axis of the prefrontal cortex differentially modulates dopamine neurotransmission in the shell-core subterritories of the nucleus accumbens
23. Differential effects of inescapable footshocks and of stimuli previously paired with inescapable footshocks on dopamine turnover in cortical and limbic areas of the rats
24. A review of the validity and variability of the elevated plus maze as an animal model of anxiety
25. Mesial prefrontal cortical lesions and timidity in rats: I. Reactivity to aversive stimuli
26. Mesial prefrontal cortical lesions and timidity in rats: II. Reactivity to novel stimuli
27. Alterations in behavioral responses to stressors following excitotoxin lesions of dorsomedial hypothalamic regions
28. Effect of ibotenic acid lesions of the medial prefrontal cortex on amphetamine-induced locomotion and regional brain catecholamine concentrations in the rat
29. Modulation of anxiety-related behaviours following lesions of the prelimbic or infralimbic cortex in the rat
30. Reciprocal connections between the lateral hypothalamus and the frontal complex in the rat: Electrophysiological and anatomical observations
31. Dissociation of the effects of lesions of the orbital or medial aspect of the prefrontal cortex of the rat with respect to activity
32. Functions of the frontal cortex of the rat: A comparative review
33. Animal models for human PFC-related disorders
34. Double dissociation of spatial impairments and perseveration following selective prefrontal lesions in rats
35. The effects of excitotoxic lesion of the medial prefrontal cortex on latent inhibition, prepulse inhibition, food hoarding, elevated plus maze, active avoidance and locomotor activity in the rat
36. Behavioral analogues of anxiety animal models
37. Restricted lesions to ventral prefrontal subareas block reversal learning but not visual discrimination learning in rats
38. The use of a plus-maze to measure anxiety in the mouse
39. On the effects of lindane on the plus-maze model of anxiety
40. Effects of an electrolytic lesion of the prelimbic area on anxiety-related and cognitive tasks in the rat
41. Overtraining does not mitigate contextual fear conditioning deficits produced by neurotoxic lesions of the basolateral amygdala
42. Retrograde abolition of conditional fear after excitotoxic lesions in the basolateral amygdala of rats: Absence of a temporal gradient
43. Projections of the medial and lateral prefrontal cortices to the amygdala: A Phaseolus vulgaris leucoagglutinin study in the rat
44. Differential contribution of dorsal and ventral medial prefrontal cortex to the acquisition and extinction of conditioned fear in rats
45. Extinction of emotional learning: Contribution of medial prefrontal cortex
46. Prefrontal cortical control of the autonomic nervous system: Anatomical and physiological observations
47. Excitotoxic lesions of the septum produce anxiolytic effects in the elevated plus-maze and the shock-probe burying tests
48. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning
49. Effect of sex on fear conditioning is similar for context and discrete CS in Wistar, Lewis and Fischer rat strains
50. Differential involvement of the dorsal anterior cingulate and prelimbic-infralimbic areas of the rodent prefrontal cortex in spatial working memory
51. Involvement of the prelimbic-infralimbic areas of the rodent prefrontal cortex in behavioral flexibility for place and response learning
52. Involvement of rodent prefrontal cortex subregions in strategy switching
53. A computer controlled analysis of freezing behaviour
54. Dissociating context and space within the hippocampus: Effects of complete, dorsal, and ventral excitotoxic hippocampal lesions on conditioned freezing and spatial learning
55. Anxiety enhancement in the murine elevated plus maze by immediate prior exposure to social stressors
56. Functional differences between the prelimbic and anterior cingulate regions of the rat prefrontal cortex
57. Complementary roles for the amygdala and hippocampus in aversive conditioning to explicit and contextual cues
58. Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract-tracing study with phaseolus vulgaris leucoagglutinin
59. Septal lesions potentiate freezing behavior to contextual but not to phasic conditioned stimuli in rats
60. The open-field test: A critical review
61. Functional reciprocal connections of the rat entorhinal cortex and subicular complex with the medial frontal cortex: An in vivo intracellular study