Association of novelty seeking scores and striatal dopamine D2/D3 receptor availability of healthy volunteers: Single photon emission computed tomography with 123I-iodobenzamide

Journal of the Formosan Medical Association

Volumn 109, Issue 10, 2010, Pages 736-739

  Huang, Hsiang Yu ^a,e   Lee, I Hui ^a,b   Chen, Kao Ching ^a,b   Yeh, Tzung Lieh ^a,b   Chen, Po See ^a,b,c   Yang, Yen Kuang ^a,b,c   Chiu, Nan Tsing ^b   Yao, We Jen ^b   Chen, Chia Chieh ^d  

^a NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d INSTITUTE OF NUCLEAR ENERGY RESEARCH   (Taiwan)

^e TAINAN MUNICIPAL HOSPITAL   (Taiwan)

Author keywords

Dopamine; Iodobenzamide; Novelty seeking; Single photon emission computed tomography

Indexed keywords

DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; IODOBENZAMIDE I 123; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BEHAVIOR; DOPAMINERGIC ACTIVITY; FEMALE; HUMAN; IMPULSIVENESS; MAJOR CLINICAL STUDY; MALE; NOVELTY SEEKING BEHAVIOR; PERSONALITY; PSYCHOMETRY; QUESTIONNAIRE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STRIATE CORTEX;

ADULT; CORPUS STRIATUM; EXPLORATORY BEHAVIOR; FEMALE; HUMANS; IODOBENZENES; MALE; MIDDLE AGED; PERSONALITY ASSESSMENT; PERSONALITY INVENTORY; QUESTIONNAIRES; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; TAIWAN; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; YOUNG ADULT;

EID: 77958122932     PISSN: None     EISSN: 09296646     Source Type: Journal    
DOI: 10.1016/S0929-6646(10)60119-2     Document Type: Article

References (22)

1. Cloninger CR A systematic method for clinical description and classification of personality variants. A proposal. Arch Gen Psychiatry 1987, 44:573-588.
2. Cloninger CR, Adolfsson R, Svrakic NM Mapping genes for human personality. Nat Genet 1996, 12:3-4.
3. Gelernter J, Kranzler H, Coccaro E, et al. D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects. Am J Hum Genet 1997, 61:1144-1152.
4. Zuckerman M, Cloninger CR Relationships between Cloninger's, Zuckerman's and Eysenck's dimensions of personality. Pers Individual Differences 1996, 21:283-285.
5. Miettunen J, Lauronen E, Kantojarvi L, et al. Inter-correlations between Cloninger's temperament dimensions-a meta-analysis. Psychiatry Res 2008, 160:106-114.
6. Benjamin J, Li L, Patterson C, et al. Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking. Nat Genet 1996, 12:81-84.
7. Ebstein RP, Novick O, Umansky R, et al. Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of novelty seeking. Nat Genet 1996, 12:78-80.
8. Gerra G, Zaimovic A, Timpano M, et al. Neuroendocrine correlates of temperamental traits in humans. Psychoneu-roendocrinology 2000, 25:479-496.
9. Noble EP, Ozkaragoz TZ, Ritchie TL, et al. D2 and D4 dopa-mine receptor polymorphisms and personality. Am J Med Genet 1998, 81:257-267.
10. Bardo MT, Donohew RL, Harrington NG Psychobiology of novelty seeking and drug seeking behavior. Behav Brain Res 1996, 77:23-43.
11. Bodi N, Keri S, Nagy H, et al. Reward-learning and the novelty-seeking personality: a between- and within-subjects study of the effects of dopamine agonists on young Parkinson's patients. Brain 2009, 132:2385-2395.
12. Kaasinen V, Rinne JO Functional imaging studies of dopa-mine system and cognition in normal aging and Parkinson's disease. Neurosci Biobehav Rev 2002, 26:785-793.
13. Sheehan DV, Lecrubier Y, Sheehan KH, et al. The MiniInternational Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998, 59(Suppl 20):22-57.
14. Chen PS, Yang YK, Lee YS, et al. Correlation between different memory systems and striatal dopamine D2/D3 receptor density: a single photon emission computed tomography study. Psychol Med 2005, 35:197-204.
15. Brucke T, Podreka I, Angelberger P, et al. Dopamine D2 receptor imaging with SPECT: studies in different neuropsychi-atric disorders. J Cereb Blood Flow Metab 1991, 11:220-228.
16. Toyama H, Ichise M, Ballinger JR, et al. Dopamine D2 receptor SPECT imaging: basic in vivo characteristics and clinical applications of 123I-IBZM in humans. Ann Nucl Med 1993, 7:29-38.
17. Cloninger CR, Przybeck TR, Svrakic DM The Tridimensional Personality Questionnaire: U.S. normative data. Psychol Rep 1991, 69:1047-1057.
18. Chen WJ, Chen HM, Chen CC, et al. Cloninger's Tridimensional Personality Questionnaire: psychometric properties and construct validity in Taiwanese adults. Compr Psychiatry 2002, 43:158-166.
19. Miettunen J, Kantojarvi L, Ekelund J, et al. A large population cohort provides normative data for investigation of temperament. Acta Psychiatr Scand 2004, 110:150-157.
20. Tomer R, Aharon-Peretz J Novelty seeking and harm avoidance in Parkinson's disease: effects of asymmetric dopamine deficiency. J Neurol Neurosurg Psychiatry 2004, 75:972-975.
21. Lind NM, Gjedde A, Moustgaard A, et al. Behavioral response to novelty correlates with dopamine receptor availability in striatum of Gottingen minipigs. Behav Brain Res 2005, 164:172-177.
22. Zald DH, Cowan RL, Riccardi P, et al. Midbrain dopamine receptor availability is inversely associated with novelty-seeking traits in humans. J Neurosci 2008, 28:14372-14378.