The effect of ethanol and its metabolism on fibrinolysis

Thrombosis and Haemostasis

Volumn 104, Issue 4, 2010, Pages 724-733

  Pieters, Marlien ^a   Vorster, Hester H ^a   Jerling, Johann C ^a   Venter, Christine S ^a   Kotze, Retha C M ^a   Bornman, Elsabe ^a   Malfliet, Joyce J M C ^b   Rijken, Dingeman C ^b  

^a NORTH WEST UNIVERSITY   (South Africa)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Acetate; Alcohol; Fibrinolysis; PAI 1act; tPAact

Indexed keywords

ACETIC ACID; ALCOHOL;

ADULT; ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ARTICLE; BLOOD CLOT; BLOOD CLOT LYSIS; CARDIOVASCULAR DISEASE; CAUCASIAN; CONTROLLED STUDY; FIBRINOLYSIS; HEMOSTASIS; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL;

ACETATES; ADULT; BIOLOGICAL MARKERS; BLOOD CELLS; BLOOD COAGULATION FACTORS; CELLS, CULTURED; ETHANOL; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; FIBRINOLYSIS; HUMANS; MALE; PLASMINOGEN ACTIVATOR INHIBITOR 1;

EID: 77958119941     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH10-01-0048     Document Type: Article

References (35)

1. Klatsky AL, Armstrong MA, Friedman GD. Risk of cardiovascular mortality in alcohol drinkers, ex-drinkers and nondrinkers. Am J Cardiol 1990; 66: 1237-1242.
2. Lazarus NB, Kaplan GA, Cohen RD, et al. Change in alcohol consumption and risk of death from all causes and from ischaemic heart disease. Br Med J 1991; 303: 553-556.
3. Rimm EB, Williams P, Fosher K, et al. Moderate alcohol intake and lower risk of coronary heart disease: meta-analysis of effects on lipids and haemostatic factors. Br Med J 1999; 319: 1523-1528.
4. Mukamal KJ, Jadhav PP, D'Agostino RB, et al. Alcohol consumption and hemostatic factors: analysis of the Framingham Offspring cohort. Circulation 2001; 104: 1367-1373.
5. Salem RO, Laposata M. Effects of alcohol on hemostasis. Am J Clin Pathol 2005; 123: S96-105.
6. Biyik I, Ergene O. Alcohol and acute myocardial infarction. J Int Med Res 2007; 35: 46-51.
7. Van de Wiel A, Van Golde PM, Kraaijenhagen RJ, et al. Acute inhibitory effect of alcohol on fibrinolysis. Eur J Clin Invest 2001; 31: 164-170.
8. Van Golde PM, Hart HC, Kraaijenhagen RJ, et al. Regular alcohol intake and fibrinolysis. Neth J Med 2002; 60: 285-288.
9. Hendriks HF, Veenstra J, Velthuis-te Wierik EJ, et al. Effect of moderate dose of alcohol with evening meal on fibrinolytic factors. Br Med J 1994; 308: 1003-1006. (Pubitemid 24115033)
10. Paton A. Alcohol in the body. Br Med J 2005; 330: 85-87.
11. Crouse JR, Gerson CD, DeCarli LM, et al. Role of acetate in the reduction of plasma free fatty acids produced by ethanol in man. J Lipid Res 1968; 9: 509-512.
12. Siler SQ, Neese RA, Hellerstein MK. De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption. Am J Clin Nutr 1999; 70: 928-936.
13. Weston AT, Petosa R, Pate RR. Validation of an instrument for measurement of physical activity in youth. Med Sci Sports Exerc 1997; 29: 138-143. (Pubitemid 27043151)
14. Ainsworth BE, Haskell WL, Whitt MC, et al. Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc 2000; 32: S498-S504.
15. Rijken DC, Hoegee-de Nobel E, Jie AF, et al. Development of a new test for the global fibrinolytic capacity in whole blood. J Thromb Haemost 2008; 6: 151-157.
16. Lisman T, de Groot PG, Meijers JC, et al. Reduced plasma fibrinolytic potential is a risk factor for venous thrombosis. Blood 2005; 105: 1102-1105. (Pubitemid 40170881)
17. Samarakoon R, Higgins PJ. Integration of non-SMAD and SMAD signaling in TGF-beta1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells. Thromb Haemost 2008; 100: 976-983.
18. Szabo G, Verma BK, Fogarasi M, et al. Induction of transforming growth factorbeta and prostaglandin E2 production by ethanol in human monocytes. J Leukoc Biol 1992; 52: 602-610. (Pubitemid 23016033)
19. Van Golde PM, Kraaijenhagen RJ, Bouma BN, et al. No acute effect of red wine on the coagulation pathway in healthy men. Alcohol 2003; 29: 183-186.
20. Rimm EB, Giovannucci EL, Willett WC, et al. Prospective study of alcohol consumption and risk of coronary disease in men. Lancet 1991; 338: 464-468.
21. Wannamethee SG, Lowe GD, Shaper G, et al. The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men. Thromb Haemost 2003; 90: 1080-1087. (Pubitemid 38004427)
22. Veenstra J, Kluft C, Ockhuizen TH, et al. Effects of moderate alcohol consumption on platelet function, tissue-type plasminogen activator and plasminogen activator inhibitor. Thromb Haemost 1990; 63: 345-348. (Pubitemid 20214704)
23. Numminen H, Syrjala M, Benthin G, et al. The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. Stroke 2000; 31: 1269-1273. (Pubitemid 30351244)
24. Sierksma A, Van der Gaag MS, Schaafsma G, et al. Moderate alcohol consumption and fibrinolytic factors of pre- and postmenopausal women. Nutrition Research 2001; 21: 171-181. (Pubitemid 32222267)
25. Olsen H, Osterud B. Effects of ethanol on human blood fibrinolysis and coagulation. Alcohol 1987; 1: 591-594.
26. Dellas C, Loskutoff DJ. Historical analysis of PAI-1 from its discovery to its potential role in cell motility and disease. Thromb Haemost 2005; 93: 631-640. (Pubitemid 40485397)
27. Szabo G, Mandrekar P, Girouard L, et al. Regulation of human monocyte functions by acute ethanol treatment: decreased tumor necrosis factor-alpha, interleukin- 1 beta and elevated interleukin-10, and transforming growth factor-beta production. Alcohol Clin Exp Res 1996; 20: 900-907. (Pubitemid 26282325)
28. Imhof A, Koenig W. Alcohol inflammation and coronary heart disease. Addict Biol 2003; 8: 271-277. (Pubitemid 37215063)
29. Sawdey M, Podor TJ, Loskutoff DJ. Regulation of type 1 plasminogen activator inhibitor gene expression in cultured bovine aortic endothelial cells. Induction by transforming growth factor-beta, lipopolysaccharide, and tumor necrosis factoralpha. J Biol Chem 1989; 264: 10396-10401. (Pubitemid 19161600)
30. Juhan-Vague I, Pyke SD, Alessi MC, et al. Fibrinolytic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. ECAT Study Group. European Concerted Action on Thrombosis and Disabilities. Circulation 1996; 94: 2057-2063.
31. Silveira A. Postprandial triglycerides and blood coagulation. Exp Clin Endocrinol Diabetes 2001; 109: S527-S532.
32. Krebs M, Geiger M, Polak K, et al. Increased plasma levels of plasminogen activator inhibitor-1 and soluble vascular cell adhesion molecule after triacylglycerol infusion in man. Thromb Haemost 2003; 90: 422-428. (Pubitemid 37138766)
33. Chen Y, Schneider DJ. The independence of signaling pathways mediating increased expression of plasminogen activator inhibitor type 1 in HepG2 cells exposed to free fatty acids or triglycerides. Int J Exp Diabetes Res 2002; 3: 109-118. (Pubitemid 34477465)
34. Stiko-Rahm A, Wiman B, Hamsten A, et al. Secretion of plasminogen activator inhibitor- 1 from cultured human umbilical vein endothelial cells is induced by very low density lipoprotein. Arteriosclerosis 1990; 10: 1067-1073.
35. Eriksson P, Nilsson L, Karpe F, et al. Very-low-density lipoprotein response element in the promoter region of the human plasminogen activator inhibitor-1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia. Arterioscler Thromb Vasc Biol 1998; 18: 20-26. (Pubitemid 28047594)