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Volumn , Issue SPRI, 2008, Pages 72-76

Why is it still drug discovery?

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL STRUCTURE; COMPUTER PROGRAM; DRUG ABSORPTION; DRUG DESIGN; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG INDUSTRY; DRUG METABOLISM; DRUG RESEARCH; DRUG SYNTHESIS; SHORT SURVEY; STRUCTURE ACTIVITY RELATION;

EID: 77958116450     PISSN: 1364369X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey
Times cited : (8)

References (16)
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  • 2
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    • Dimasi JA, Hansen RW and Grabowski HG, The price of innovation: new estimates of drug development costs, J Health Econ 22: pp151-185, 2003
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  • 5
    • 4043062916 scopus 로고    scopus 로고
    • De novo drug design: Integration of structure-based and ligand-based methods
    • Dean PM, Lloyd DG and Todorov NP, De novo drug design: integration of structure-based and ligand-based methods, Curr Opin Drug Discov Devel 7: pp347-353, 2004
    • (2004) Curr Opin Drug Discov Devel , vol.7 , pp. 347-353
    • Dean, P.M.1    Lloyd, D.G.2    Todorov, N.P.3
  • 6
    • 0037082199 scopus 로고    scopus 로고
    • The emerging importance of predictive ADME simulation in drug discovery
    • Selick HE, Beresford AP and Tarbit MH, The emerging importance of predictive ADME simulation in drug discovery, Drug Discov Today 7: pp109-116, 2002
    • (2002) Drug Discov Today , vol.7 , pp. 109-116
    • Selick, H.E.1    Beresford, A.P.2    Tarbit, M.H.3
  • 9
    • 0031552362 scopus 로고    scopus 로고
    • Development and validation of a genetic algorithm for flexible docking
    • Jones G, Willett P, Glen RC, Leach AR and Taylor R, Development and validation of a genetic algorithm for flexible docking, J Mol Biol 267: pp727-748, 1997
    • (1997) J Mol Biol , vol.267 , pp. 727-748
    • Jones, G.1    Willett, P.2    Glen, R.C.3    Leach, A.R.4    Taylor, R.5
  • 10
    • 0003955925 scopus 로고
    • Fundamentals and Applications in Chemistry and Biology
    • Hansch C and Leo A, Exploring QSAR Volume 1: Fundamentals and Applications in Chemistry and Biology, 1995
    • (1995) Exploring QSAR , vol.1
    • Hansch, C.1    Leo, A.2
  • 11
    • 0037364162 scopus 로고    scopus 로고
    • ADMET in silico modelling: Towards prediction paradise?
    • Van de Waterbeemd H and Gifford E, ADMET in silico modelling: towards prediction paradise? Nat Rev Drug Discov 2: pp192-204, 2003
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 192-204
    • Van De Waterbeemd, H.1    Gifford, E.2
  • 12
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski CA, Lombardo F, Dominy BW and Feeney PJ, Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings, Adv Drug Deliv Rev 23: pp3-25, 1997
    • (1997) Adv Drug Deliv Rev , vol.23 , pp. 3-25
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 13
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    • Computational models for cytochrome P450: A predictive electronic model for aromatic oxidation and hydrogen atom abstraction
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  • 16
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    • Focus on Success: Using a Probabilistic Approach to Achieve an Optimal Balance of Compound Properties in Drug Discovery
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.