A stereochemical glimpse of the active site of the 8-17 deoxyribozyme from iodine-mediated cross-links formed with the substrate's scissile site

Biochemistry

Volumn 49, Issue 42, 2010, Pages 9072-9077

  Sekhon, Gurpreet S ^a   Sen, Dipankar ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; DNA; INDUSTRIAL CHEMICALS; IODINE; RNA;

ACID BASE; ACTIVE SITE; CATALYTIC RATES; CLEAVAGE SITES; DEOXYRIBOZYMES; DNAZYME; PHOSPHODIESTERS; PHOSPHOROTHIOATES; REACTION SITES; RIBOZYMES; SCISSILE SITE;

SUBSTRATES;

DEOXYRIBOZYME; IODINE; PHOSPHOROTHIOIC ACID; CROSS LINKING REAGENT; RNA-CLEAVING DNA 8-17;

ARTICLE; CROSS LINKING; ENZYME ACTIVE SITE; PRIORITY JOURNAL; STEREOCHEMISTRY; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; ENZYME SPECIFICITY; GENETICS; METABOLISM; STEREOISOMERISM;

CATALYTIC DOMAIN; CROSS-LINKING REAGENTS; DNA, CATALYTIC; MODELS, CHEMICAL; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 77958100827     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1013547     Document Type: Article

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