Characterization of Housing-Related Spontaneous Variations of Gut Microbiota and Expression of Toll-Like Receptors 2 and 4 in Rats

Microbial Ecology

Volumn 60, Issue 3, 2010, Pages 691-702

  Terán Ventura, Evangelina ^a   Roca, M ^c   Martin, Maria Teresa ^a,b   Abarca, Maria Lourdes ^a   Martinez, Vicente ^a   Vergara, Patri ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c CENTRE DE RECERCA EN SANITAT ANIMAL CRESA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; TLR2 PROTEIN, RAT; TLR4 PROTEIN, RAT; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ANIMAL; ANIMAL HOUSING; ARTICLE; BACTERIUM; BIODIVERSITY; CECUM; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; GENETICS; MALE; METABOLISM; METAGENOME; MICROBIOLOGY; RAT; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SPRAGUE DAWLEY RAT;

ANIMALS; BACTERIA; BIODIVERSITY; CECUM; DNA, BACTERIAL; GENE EXPRESSION; HOUSING, ANIMAL; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; METAGENOME; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RATS; RATS, SPRAGUE-DAWLEY; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

ANIMALIA; BACTERIA (MICROORGANISMS); BACTEROIDES; BACTEROIDES (CLASS); BACTEROIDES SP.; BIFIDOBACTERIUM; CLOSTRIDIUM; RATTUS;

EID: 77958096095     PISSN: 00953628     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00248-010-9737-z     Document Type: Article

References (47)

1. Amann RI, Krumholz L, Stahl DA (1990) Fluorescent-oligonucleotide probing of whole cells for determinative, phylogenetic, and environmental studies in microbiology. J Bacteriol 172: 762-770.
2. Andoh A, Benno Y, Kanauchi O, Fujiyama Y (2009) Recent advances in molecular approaches to gut microbiota in inflammatory bowel disease. Curr Pharm Des 15: 2066-2073.
3. Bäckhed F, Normark S, Schweda EK, Oscarson S, Richter-Dahlfors A (2003) Structural requirements for TLR4-mediated LPS signalling: a biological role for LPS modifications. Microbes Infect 12: 1057-1063.
4. Berg RD (1996) The indigenous gastrointestinal microflora. Trends Microbiol 4: 430-435.
5. Camp JG, Kanther M, Semova I, Rawls JF (2009) Patterns and scales in gastrointestinal microbial ecology. Gastroenterology 136: 1989-2002.
6. Cario E (2005) Bacterial interactions with cells of the intestinal mucosa: toll-like receptors and NOD2. Gut 54: 1182-1193.
7. Collado MC, Isolauri E, Salminen S, Sanz Y (2009) The impact of probiotic on gut health. Curr Drug Metab 10: 68-78.
8. Collins SM, Bercik P (2009) The relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease. Gastroenterology 136: 2003-2014.
9. Dinoto A, Suksomcheep A, Ishizuka S, Kimura H, Hanada S, Kamagata Y, Asano K, Tomita F, Yokota A (2006) Modulation of rat cecal microbiota by administration of raffinose and encapsulated Bifidobacterium breve. Appl Environ Microbiol 72: 784-792.
10. Duncan SH, Scott KP, Ramsay AG, Harmsen HJ, Welling GW, Stewart CS, Flint HJ (2003) Effects of alternative dietary substrates on competition between human colonic bacteria in an anaerobic fermentor system. Appl Environ Microbiol 69: 1136-1142.
11. Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, Gill SR, Nelson KE, Relman DA (2005) Diversity of the human intestinal microbial flora. Science 5728: 1635-1638.
12. Fujisawa M, Kiyosue M, Hori M, Ozaki H (2006) Identification of Card15/Nod2 mRNA in intestinal tissue of experimentally induced colitis in rats. J Vet Med Sci 68: 701-708.
13. Galdeano CM, Perdigon G (2006) The probiotic bacterium Lactobacillus casei induces activation of the gut mucosal immune system through innate immunity. Clin Vaccine Immunol 13: 219-226.
14. Garcia-Lafuente A, Antolin M, Guarner F, Crespo E, Salas A, Forcada P, Laguarda M, Gavalda J, Baena JA, Vilaseca J, Malagelada JR (1997) Incrimination of anaerobic bacteria in the induction of experimental colitis. Am J Physiol 272: G10-G15.
15. Guarner F, Bourdet-Sicard R, Brandtzaeg P, Gill HS, McGuirk P, van EW, Versalovic J, Weinstock JV, Rook GA (2006) Mechanisms of disease: the hygiene hypothesis revisited. Nat Clin Pract Gastroenterol Hepatol 3: 275-284.
16. Heine H, Delude RL, Monks BG, Espevik T, Golenbock DT (1999) Bacterial lipopolysaccharide induces expression of the stress response genes hop and H411. J Biol Chem 30: 21049-21055.
17. Hoentjen F, Welling GW, Harmsen HJ, Zhang X, Snart J, Tannock GW, Lien K, Churchill TA, Lupicki M, Dieleman LA (2005) Reduction of colitis by prebiotics in HLA-B27 transgenic rats is associated with microflora changes and immunomodulation. Inflamm Bowel Dis 11: 977-985.
18. Hojberg O, Canibe N, Poulsen HD, Hedemann MS, Jensen BB (2005) Influence of dietary zinc oxide and copper sulfate on the gastrointestinal ecosystem in newly weaned piglets. Appl Environ Microbiol 71: 2267-2277.
19. Karlsson H, Hessle AR (2002) Innate immune responses of human neonatal cells to bacteria from the normal gastrointestinal flora. Infect Immun 70: 6688-6696.
20. Kim SC, Tonkonogy SL, Karrasch T, Jobin C, Sartor RB (2007) Dual-association of gnotobiotic IL-10-/- mice with 2 nonpathogenic commensal bacteria induces aggressive pancolitis. Inflamm Bowel Dis 13: 1457-1466.
21. Kitts CL (2001) Terminal restriction fragment patterns: a tool for comparing microbial communities and assessing community dynamics. Curr Issues Intest Microbiol 2: 17-25.
22. Looijer-van Langen MA, Dieleman LA (2009) Prebiotics in chronic intestinal inflammation. Inflamm Bowel Dis 15: 454-462.
23. Mai V, Katki HA, Harmsen H, Gallaher D, Schatzkin A, Baer DJ, Clevidence B (2004) Effects of a controlled diet and black tea drinking on the fecal microflora composition and the fecal bile acid profile of human volunteers in a double-blinded randomized feeding study. J Nutr 134: 473-478.
24. Marteau PR (2002) Probiotics in clinical conditions. Clin Rev Allergy Immunol 22: 255-273.
25. Montesi A, Garcia-Albiach R, Pozuelo MJ, Pintado C, Goni I, Rotger R (2005) Molecular and microbiological analysis of caecal microbiota in rats fed with diets supplemented either with prebiotics or probiotics. Int J Food Microbiol 98: 281-289.
26. Okada H, Kuhn C, Feillet H, Bach JF (2010) The 'hygiene hypothesis' for autoimmune and allergic diseases: an update. Clin Exp Immunol 160: 1-9.
27. Ootsubo M, Shimizu T, Tanaka R, Sawabe T, Tajima K, Yoshimizu M, Ezura Y, Ezaki T, Oyaizu H (2002) Oligonucleotide probe for detecting Enterobacteriaceae by in situ hybridization. J Appl Microbiol 93: 60-68.
28. Porras M, Martin MT, Soler M, Vergara P (2004) Intestinal motor disorders associated with cyclical bacterial overgrowth in a rat model of enteritis. Am J Physiol Gastrointest Liver Physiol 287: G58-G64.
29. Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R (2004) Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118: 229-241.
30. Rolhion N, Rfeuille-Michaud A (2007) Adherent-invasive Escherichia coli in inflammatory bowel disease. Inflamm Bowel Dis 13: 1277-1283.
31. Rousseaux C, Thuru X, Gelot A, Barnich N, Neut C, Dubuquoy L, Dubuquoy C, Merour E, Geboes K, Chamaillard M, Ouwehand A, Leyer G, Carcano D, Colombel JF, Ardid D, Desreumaux P (2007) Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors. Nat Med 13: 35-37.
32. Ruiz PA, Hoffmann M, Szcesny S, Blaut M, Haller D (2005) Innate mechanisms for Bifidobacterium lactis to activate transient pro-inflammatory host responses in intestinal epithelial cells after the colonization of germ-free rats. Immunology 115: 441-450.
33. Salzman NH, de Paterson JH, Harmsen HJ, Welling GW, Bos A (2002) Analysis of 16S libraries of mouse gastrointestinal microflora reveals a large new group of mouse intestinal bacteria. Microbiology 148: 3651-3660.
34. Setoyama H, Imaoka A, Ishikawa H, Umesaki Y (2003) Prevention of gut inflammation by Bifidobacterium in dextran sulfate-treated gnotobiotic mice associated with Bacteroides strains isolated from ulcerative colitis patients. Microbes Infect 5: 115-122.
35. Siggers RH, Siggers J, Boye M, Thymann T, Mølbak L, Leser T, Jensen BB, Sangild PT (2008) Early administration of probiotics alters bacterial colonization and limits diet-induced gut dysfunction and severity of necrotizing enterocolitis in preterm pigs. J Nutr 138: 1437-1444.
36. Silva MA, Jury J, Porras M, Vergara P, Perdue MH (2008) Intestinal epithelial barrier dysfunction and dendritic cell redistribution during early stages of inflammation in the rat: role for TLR-2 and -4 blockage. Inflamm Bowel Dis 14: 632-644.
37. Swidsinski A, Weber J, Loening-Baucke V, Hale LP, Lochs H (2005) Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease. J Clin Microbiol 43: 3380-3389.
38. Szebeni B, Veres G, Dezsofi A, Rusai K, Vannay A, Mraz M, Majorova E, Arato A (2008) Increased expression of toll-like receptor (TLR) 2 and TLR4 in the colonic mucosa of children with inflammatory bowel disease. Clin Exp Immunol 151: 34-41.
39. Takaishi H, Matsuki T, Nakazawa A, Takada T, Kado S, Asahara T, Kamada N, Sakuraba A, Yajima T, Higuchi H, Inoue N, Ogata H, Iwao Y, Nomoto K, Tanaka R, Hibi T (2008) Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease. Int J Med Microbiol 298: 463-472.
40. Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K, Akira S (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11: 443-451.
41. Tilg H, Moschen AR, Kaser A (2009) Obesity and the microbiota. Gastroenterology 136: 1476-1483.
42. Vaahtovuo J, Korkeamaki M, Munukka E, Viljanen MK, Toivanen P (2005) Quantification of bacteria in human feces using 16S rRNA-hybridization, DNA-staining and flow cytometry. J Microbiol Methods 63: 276-286.
43. Verdú EF, Bercik P, Verma-Gandhu M, Huang XX, Blennerhassett P, Jackson W, Mao Y, Wang L, Rochat F, Collins S (2006) Specific probiotic therapy attenuates antibiotic induced visceral hypersensitivity in mice. Gut 55: 182-190.
44. Wirtz S, Neurath MF (2007) Mouse models of inflammatory bowel disease. Adv Drug Deliv Rev 59: 1073-1083.
45. Wohlgemuth S, Haller D, Blaut M, Loh G (2009) Reduced microbial diversity and high numbers of one single Escherichia coli strain in the intestine of colitic mice. Environ Microbiol 11: 1562-1571.
46. Wohlsen T, Bayliss J, Gray B, Bates J, Katouli M (2006) Evaluation of an alternative method for the enumeration and confirmation of Clostridium perfringens from treated and untreated sewages. Lett Appl Microbiol 42: 438-444.
47. Xavier RJ, Podolsky DK (2007) Unravelling the pathogenesis of inflammatory bowel disease. Nature 448: 427-434.