-
1
-
-
78651010566
-
Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroylglutamic acid (aminopterin)
-
Farber S, Diamond LK, Mercer RD, Sylvester RF, Wolf JA (1948) Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroylglutamic acid (aminopterin). N Engl J Med 238, 787-93.
-
(1948)
N Engl J Med
, vol.238
, pp. 787-793
-
-
Farber, S.1
Diamond, L.K.2
Mercer, R.D.3
Sylvester, R.F.4
Wolf, J.A.5
-
2
-
-
77958086362
-
Pharmacology of cancer chemotherapy: antimetabolite - methotrexate
-
DeVita VT Jr, Hellman S, Rosenberg SA, 8th edn, Lippincott Williams & Wilkins, Philadeplhia.
-
Devita VT, Lawrence TS, Rosenberg SA, DePinto RA, Weinberg RA (2008) Pharmacology of cancer chemotherapy: antimetabolite - methotrexate. In: DeVita VT Jr, Hellman S, Rosenberg SA (eds) Principles and Practice of Oncology, 8th edn, pp 427-28. Lippincott Williams & Wilkins, Philadeplhia.
-
(2008)
Principles and Practice of Oncology
, pp. 427-428
-
-
Devita, V.T.1
Lawrence, T.S.2
Rosenberg, S.A.3
DePinto, R.A.4
Weinberg, R.A.5
-
3
-
-
0023503165
-
High- dose methotrexate: a critical reappraisal
-
Ackland SP, Schilsky RL (1987) High- dose methotrexate: a critical reappraisal. J Clin Oncol 5, 2017-31.
-
(1987)
J Clin Oncol
, vol.5
, pp. 2017-2031
-
-
Ackland, S.P.1
Schilsky, R.L.2
-
4
-
-
0029788523
-
Concepts in use of high-dose methotrexate therapy
-
Treon SP, Chabner BA (1996) Concepts in use of high-dose methotrexate therapy. Clin Chem 42, 1322-9.
-
(1996)
Clin Chem
, vol.42
, pp. 1322-1329
-
-
Treon, S.P.1
Chabner, B.A.2
-
5
-
-
76549239323
-
Therapeutic suppression of tissue reactivity. Effect of aminopterin in Rheumatoid Arthritis and psoriasis
-
Gubner R, August S, Ginsberg V (1951) Therapeutic suppression of tissue reactivity. Effect of aminopterin in Rheumatoid Arthritis and psoriasis. Am J Med Sci 221, 176-82.
-
(1951)
Am J Med Sci
, vol.221
, pp. 176-182
-
-
Gubner, R.1
August, S.2
Ginsberg, V.3
-
6
-
-
0014436555
-
Treatment of dermatomyositis with methotrexate
-
Malaviya AN, Many A, Schwartz RS (1968) Treatment of dermatomyositis with methotrexate. Lancet 2, 485-8.
-
(1968)
Lancet
, vol.2
, pp. 485-488
-
-
Malaviya, A.N.1
Many, A.2
Schwartz, R.S.3
-
7
-
-
0021080093
-
Methotrexate in rheumatoid arthritis: 15 years experience
-
Hoffmeister RT (1983) Methotrexate in rheumatoid arthritis: 15 years experience. Am J Med 75(6A), 69-73.
-
(1983)
Am J Med
, vol.75 A
, Issue.6
, pp. 69-73
-
-
Hoffmeister, R.T.1
-
8
-
-
0000685404
-
Methotrexate in rheumatoid arthritis
-
Hoffmeister RT (1972) Methotrexate in rheumatoid arthritis. Arthritis Rheum 15, 114.
-
(1972)
Arthritis Rheum
, vol.15
, pp. 114
-
-
Hoffmeister, R.T.1
-
9
-
-
0021923633
-
Efficacy of low-dose methotrexate in rheumatoid arthritis
-
Weinblatt ME, Coblyn JS, Fox DA, et al. (1985) Efficacy of low-dose methotrexate in rheumatoid arthritis. N Engl J Med 312, 818-22.
-
(1985)
N Engl J Med
, vol.312
, pp. 818-822
-
-
Weinblatt, M.E.1
Coblyn, J.S.2
Fox, D.A.3
-
10
-
-
0022137053
-
Weekly pulse methotrexate in rheumatoid arthritis. Clinical and immunologic effects in a randomized, double-blind study
-
Andersen PA, West SG, O'Dell JR, Via CS, Claypool RG, Kotzin BL (1985) Weekly pulse methotrexate in rheumatoid arthritis. Clinical and immunologic effects in a randomized, double-blind study. Ann Intern Med 103, 489-96.
-
(1985)
Ann Intern Med
, vol.103
, pp. 489-496
-
-
Andersen, P.A.1
West, S.G.2
O'Dell, J.R.3
Via, C.S.4
Claypool, R.G.5
Kotzin, B.L.6
-
11
-
-
0024589484
-
Increasing methotrexate effect with increasing dose in the treatment of resistant rheumatoid arthritis
-
Furst DE, Koehnke R, Burmeister LF, Kohler J, Cargill I (1989) Increasing methotrexate effect with increasing dose in the treatment of resistant rheumatoid arthritis. J Rheumatol 16, 313-20.
-
(1989)
J Rheumatol
, vol.16
, pp. 313-320
-
-
Furst, D.E.1
Koehnke, R.2
Burmeister, L.F.3
Kohler, J.4
Cargill, I.5
-
12
-
-
0028306446
-
Tolerability of methotrexate starting with 15 or 25 mg/week for rheumatoid arthritis
-
Schnabel A, Reinhold-Keller E, Willmann V, Gross WL (1994) Tolerability of methotrexate starting with 15 or 25 mg/week for rheumatoid arthritis. Rheumatol Int 14, 33-8.
-
(1994)
Rheumatol Int
, vol.14
, pp. 33-38
-
-
Schnabel, A.1
Reinhold-Keller, E.2
Willmann, V.3
Gross, W.L.4
-
13
-
-
35648991026
-
Intensive treatment with methotrexate in early rheumatoid arthritis: aiming for remission. Computer Assisted Management in Early Rheumatoid Arthritis (CAMERA, an open-label strategy trial)
-
Verstappen SM, Jacobs JW, Van Der Veen MJ, et al. (2007) Intensive treatment with methotrexate in early rheumatoid arthritis: aiming for remission. Computer Assisted Management in Early Rheumatoid Arthritis (CAMERA, an open-label strategy trial). Ann Rheum Dis 66, 1443-9.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 1443-1449
-
-
Verstappen, S.M.1
Jacobs, J.W.2
Van Der Veen, M.J.3
-
14
-
-
67549096874
-
Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative
-
Visser K, Katchamart W, Loza E, Martinez-Lopez JA, Salliot C, Trudeau J (2009) Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative. Ann Rheum Dis 68, 1086-93.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1086-1093
-
-
Visser, K.1
Katchamart, W.2
Loza, E.3
Martinez-Lopez, J.A.4
Salliot, C.5
Trudeau, J.6
-
15
-
-
67650156848
-
An update on methotrexate
-
Braun J, Rau R (2009) An update on methotrexate. Curr Opin Rheumatol 21, 216-23.
-
(2009)
Curr Opin Rheumatol
, vol.21
, pp. 216-223
-
-
Braun, J.1
Rau, R.2
-
16
-
-
0142124934
-
Methotrexate as the 'anchor drug' for the treatment of early rheumatoid arthritis
-
Pincus T, Yazici Y, Sokka T, Aletaha D, Smolen JS (2003) Methotrexate as the 'anchor drug' for the treatment of early rheumatoid arthritis. Clin Exp Rheumatol 21, S179-85.
-
(2003)
Clin Exp Rheumatol
, vol.21
-
-
Pincus, T.1
Yazici, Y.2
Sokka, T.3
Aletaha, D.4
Smolen, J.S.5
-
17
-
-
67549101312
-
Optimal dosage and route of administration of methotrexate in rheumatoid arthritis: a systematic review of the literature
-
Visser K, Van Der HD (2009) Optimal dosage and route of administration of methotrexate in rheumatoid arthritis: a systematic review of the literature. Ann Rheum Dis 68, 1094-9.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1094-1099
-
-
Visser, K.1
Van Der, H.D.2
-
18
-
-
0029788523
-
Concepts in use of high-dose methotrexate therapy
-
Treon SP, Chabner BA (1996) Concepts in use of high-dose methotrexate therapy. Clin Chem 42 8 (B), 1322-9.
-
(1996)
Clin Chem
, vol.42 B
, Issue.8
, pp. 1322-1329
-
-
Treon, S.P.1
Chabner, B.A.2
-
19
-
-
0017713675
-
Incidence of drug-related deaths secondary to high-dose methotrexate and citrovorum factor administration
-
Von Hoff DD, Penta IS, Helman U, Slavik M (1977) Incidence of drug-related deaths secondary to high-dose methotrexate and citrovorum factor administration. Cancer Treat Rep 61, 745-8.
-
(1977)
Cancer Treat Rep
, vol.61
, pp. 745-748
-
-
Von Hoff, D.D.1
Penta, I.S.2
Helman, U.3
Slavik, M.4
-
20
-
-
65949115490
-
High-dose methotrexate for elderly patients with primary CNS lymphoma
-
Zhu J-J, Gerstner ER, Engler DA, et al. (2009) High-dose methotrexate for elderly patients with primary CNS lymphoma. Neuro Oncol 11, 211-5.
-
(2009)
Neuro Oncol
, vol.11
, pp. 211-215
-
-
Zhu, J.-J.1
Gerstner, E.R.2
Engler, D.A.3
-
21
-
-
0019472047
-
Methotrexate treatment of squamous-cell head and neck cancers: dose-response evaluation
-
Woods RL, Fox RM, Tattersall MHN (1981) Methotrexate treatment of squamous-cell head and neck cancers: dose-response evaluation. Br Med J 282, 600-2.
-
(1981)
Br Med J
, vol.282
, pp. 600-602
-
-
Woods, R.L.1
Fox, R.M.2
Tattersall, M.H.N.3
-
22
-
-
0017255763
-
Acute and chronic effects of methotrexate on hepatic, pulmonary, and skeletal systems
-
Nesbit M, Krivit W, Heyn R, Sharp H (2006) Acute and chronic effects of methotrexate on hepatic, pulmonary, and skeletal systems. Cancer 37(Suppl 2), 1048-54.
-
(2006)
Cancer
, vol.37
, Issue.SUPPL 2
, pp. 1048-1054
-
-
Nesbit, M.1
Krivit, W.2
Heyn, R.3
Sharp, H.4
-
23
-
-
0013901315
-
Hepatotoxic effects of methotrexate
-
Hersh EM, Wong VG, Henderson ES, Freireich EJ (2006) Hepatotoxic effects of methotrexate. Cancer 19, 600-6.
-
(2006)
Cancer
, vol.19
, pp. 600-606
-
-
Hersh, E.M.1
Wong, V.G.2
Henderson, E.S.3
Freireich, E.J.4
-
24
-
-
0011328548
-
Cancer chemotherapy and the liver
-
Macdonald J (1998) Cancer chemotherapy and the liver. Clin Liver Dis 2, 631-42.
-
(1998)
Clin Liver Dis
, vol.2
, pp. 631-642
-
-
Macdonald, J.1
-
25
-
-
0015442331
-
Recent advances in the chemotherapy of metastatic osteogenic sarcoma
-
Jaffe N (2006) Recent advances in the chemotherapy of metastatic osteogenic sarcoma. Cancer 30, 1627-31.
-
(2006)
Cancer
, vol.30
, pp. 1627-1631
-
-
Jaffe, N.1
-
26
-
-
77958106296
-
-
Drug-induced pulmonary toxicity eMedicine specialties > Pulmonology > iatrogenic pulmonary disorders, updated September 24, (accessed 12 May 2010).
-
Ali A, Schmidt MF (2008) Drug-induced pulmonary toxicity eMedicine specialties > Pulmonology > iatrogenic pulmonary disorders updated September 24, (accessed 12 May 2010).
-
(2008)
-
-
Ali, A.1
Schmidt, M.F.2
-
27
-
-
67549107120
-
Long term safety of methotrexate monotherapy in rheumatoid arthritis patients: a systematic literature research
-
Salliot C, Van Der Heijde D (2009) Long term safety of methotrexate monotherapy in rheumatoid arthritis patients: a systematic literature research. Ann Rheum Dis 68, 1100-4.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1100-1104
-
-
Salliot, C.1
Van Der Heijde, D.2
-
28
-
-
0037029418
-
Methotrexate and mortality in patients with rheumatoid arthritis: a prospective study
-
Choi HK, Hernan MA, Seeger JD, Robins JM, Wolfe F (2002) Methotrexate and mortality in patients with rheumatoid arthritis: a prospective study. Lancet 359, 1173-7.
-
(2002)
Lancet
, vol.359
, pp. 1173-1177
-
-
Choi, H.K.1
Hernan, M.A.2
Seeger, J.D.3
Robins, J.M.4
Wolfe, F.5
-
29
-
-
34247564814
-
Disease modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study
-
Van HalmVP, Nurmohamed MT, Twisk JW, Dijkmans BA, Voskuyl AE (2006) Disease modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study. Arthritis Res Ther 8, R151.
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Van Halm, V.P.1
Nurmohamed, M.T.2
Twisk, J.W.3
Dijkmans, B.A.4
Voskuyl, A.E.5
-
30
-
-
0033830527
-
Meta-analysis of treatment termination rates among rheumatoid arthritis patients receiving disease modifying anti-rheumatic drugs
-
Maetzel A, Wong A, Strand V, Tugwell P, Wells G, Bombardier C (2000) Meta-analysis of treatment termination rates among rheumatoid arthritis patients receiving disease modifying anti-rheumatic drugs. Rheumatology (Oxford) 39, 975-81.
-
(2000)
Rheumatology (Oxford)
, vol.39
, pp. 975-981
-
-
Maetzel, A.1
Wong, A.2
Strand, V.3
Tugwell, P.4
Wells, G.5
Bombardier, C.6
-
31
-
-
76649094231
-
Risk and management of liver toxicity during methotrexate treatment in rheumatoid and psoriatic arthritis: a systematic review of the literature
-
Visser K, Van Der Heijde DM (2009) Risk and management of liver toxicity during methotrexate treatment in rheumatoid and psoriatic arthritis: a systematic review of the literature. Clin Exp Rheumatol 27, 1017-25.
-
(2009)
Clin Exp Rheumatol
, vol.27
, pp. 1017-1025
-
-
Visser, K.1
Van Der Heijde, D.M.2
-
32
-
-
0036745010
-
Predictors of infection in rheumatoid arthritis
-
Doran MF, Crowson CS, Pond GR, O'Fallon WM, Gabriel SE (2002) Predictors of infection in rheumatoid arthritis. Arthritis Rheum 46, 2294-300.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2294-2300
-
-
Doran, M.F.1
Crowson, C.S.2
Pond, G.R.3
O'Fallon, W.M.4
Gabriel, S.E.5
-
33
-
-
33750210943
-
Rates and predictors of herpes zoster in patients with rheumatoid arthritis and non-inflammatory musculoskeletal disorders
-
Wolfe F, Michaud K, Chakravarty EF (2006) Rates and predictors of herpes zoster in patients with rheumatoid arthritis and non-inflammatory musculoskeletal disorders. Rheumatology (Oxford) 45, 1370-5.
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 1370-1375
-
-
Wolfe, F.1
Michaud, K.2
Chakravarty, E.F.3
-
34
-
-
70149083711
-
Methotrexate, rheumatoid arthritis and infection risk-what is the evidence?
-
McLean-Tooke A, Aldridge C, Waugh S, Spickett GP, Kay L (2009) Methotrexate, rheumatoid arthritis and infection risk-what is the evidence? Rheumatology (Oxford) 48, 867-71.
-
(2009)
Rheumatology (Oxford)
, vol.48
, pp. 867-871
-
-
McLean-Tooke, A.1
Aldridge, C.2
Waugh, S.3
Spickett, G.P.4
Kay, L.5
-
35
-
-
2642554059
-
Lymphoma in rheumatoid arthritis: the effect of methotrexate and anti-tumor necrosis factor therapy in 18,572 patients
-
Wolfe F, Michaud K (2004) Lymphoma in rheumatoid arthritis: the effect of methotrexate and anti-tumor necrosis factor therapy in 18,572 patients. Arthritis Rheum 50, 1740-51.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1740-1751
-
-
Wolfe, F.1
Michaud, K.2
-
36
-
-
0036624739
-
Lymphomas in rheumatoid arthritis patients treated with methotrexate: a 3-year prospective study in France
-
Mariette X, Cazals-Hatem D, Warszawki J, Liote F, Balandraud N, Sibilia J (2002) Lymphomas in rheumatoid arthritis patients treated with methotrexate: a 3-year prospective study in France. Blood 99, 3909-15.
-
(2002)
Blood
, vol.99
, pp. 3909-3915
-
-
Mariette, X.1
Cazals-Hatem, D.2
Warszawki, J.3
Liote, F.4
Balandraud, N.5
Sibilia, J.6
-
37
-
-
68049089955
-
Determinants of red blood cell methotrexate polyglutamate concentrations in rheumatoid arthritis patients receiving long-term methotrexate treatment
-
Stamp LK, O'Donnell JL, Chapman PT, et al. (2009) Determinants of red blood cell methotrexate polyglutamate concentrations in rheumatoid arthritis patients receiving long-term methotrexate treatment. Arthritis Rheum 60, 2248-56.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2248-2256
-
-
Stamp, L.K.1
O'Donnell, J.L.2
Chapman, P.T.3
-
38
-
-
0017873070
-
The clinical pharmacology of methotrexate: new applications of an old drug
-
Bleyer WA (1978) The clinical pharmacology of methotrexate: new applications of an old drug. Cancer 41, 36-51.
-
(1978)
Cancer
, vol.41
, pp. 36-51
-
-
Bleyer, W.A.1
-
39
-
-
22944470530
-
Low-Dose Methotrexate: a mainstay in the treatment of rheumatoid arthritis
-
Cronstein BN (2005) Low-Dose Methotrexate: a mainstay in the treatment of rheumatoid arthritis. Pharmacol Rev 57, 163-72.
-
(2005)
Pharmacol Rev
, vol.57
, pp. 163-172
-
-
Cronstein, B.N.1
-
40
-
-
0029898079
-
Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis
-
Bannwarth B, Pehourcq F, Schaeverbeke T, Dehais J (1996) Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis. Clin Pharmacokinet 30, 194-210.
-
(1996)
Clin Pharmacokinet
, vol.30
, pp. 194-210
-
-
Bannwarth, B.1
Pehourcq, F.2
Schaeverbeke, T.3
Dehais, J.4
-
41
-
-
11444251484
-
The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules
-
Johnston A, Gudjonsson JE, Sigmundsdottir H, Ludviksson BR, Valdimarsson H (2005) The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules. Clin Immunol 114, 154-63.
-
(2005)
Clin Immunol
, vol.114
, pp. 154-163
-
-
Johnston, A.1
Gudjonsson, J.E.2
Sigmundsdottir, H.3
Ludviksson, B.R.4
Valdimarsson, H.5
-
42
-
-
57349141486
-
Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages
-
Reiss AB, Carsons SE, Anwar K, et al. (2008) Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages. Arthritis Rheum 58, 3675-83.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3675-3683
-
-
Reiss, A.B.1
Carsons, S.E.2
Anwar, K.3
-
43
-
-
14944358734
-
Cardiovascular death in rheumatoid arthritis: a population-based study
-
Maradit-Kremers H, Nicola PJ, Crowson CS, Ballman KV, Gabriel SE (2005) Cardiovascular death in rheumatoid arthritis: a population-based study. Arthritis Rheum 52, 722-32.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 722-732
-
-
Maradit-Kremers, H.1
Nicola, P.J.2
Crowson, C.S.3
Ballman, K.V.4
Gabriel, S.E.5
-
44
-
-
20044362604
-
Lp (a) lipoprotein and lipids in patients with rheumatoid arthritis: serum levels and relationship to inflammation
-
Dursunoglu D, Evrengul H, Polat B, Tanriverdi H, Cobankara V, Kilic AKM (2005) Lp (a) lipoprotein and lipids in patients with rheumatoid arthritis: serum levels and relationship to inflammation. Rheumatol Int 25, 241-5.
-
(2005)
Rheumatol Int
, vol.25
, pp. 241-245
-
-
Dursunoglu, D.1
Evrengul, H.2
Polat, B.3
Tanriverdi, H.4
Cobankara, V.5
Kilic, A.K.M.6
-
45
-
-
84960582159
-
Efficacy of methotrexate in rheumatoid arthritis
-
Weinblatt ME (1995) Efficacy of methotrexate in rheumatoid arthritis. Brit J Rheumatol 34(Suppl 2), 43-8.
-
(1995)
Brit J Rheumatol
, vol.34
, Issue.SUPPL 2
, pp. 43-48
-
-
Weinblatt, M.E.1
-
46
-
-
0035124920
-
Platelet-Active drugs the relationship among dose, effectiveness and side effects
-
Patrono C, Coller B, Dalen JE, et al. (2001) Platelet-Active drugs the relationship among dose, effectiveness and side effects. Chest 119, 39S-63S.
-
(2001)
Chest
, vol.119
-
-
Patrono, C.1
Coller, B.2
Dalen, J.E.3
-
47
-
-
0020537396
-
Differential inhibition by aspirin of vascular and platelet prostaglandin synthesis in atherosclerotic patients
-
Weksler BB, Pett SB, Alonso D, Richter RC (1983) Differential inhibition by aspirin of vascular and platelet prostaglandin synthesis in atherosclerotic patients. N Engl J Med 308, 800-5.
-
(1983)
N Engl J Med
, vol.308
, pp. 800-805
-
-
Weksler, B.B.1
Pett, S.B.2
Alonso, D.3
Richter, R.C.4
|