Incidence of childhood diabetes in children aged less than 15 years and its clinical and metabolic characteristics at the time of diagnosis: Data from the childhood diabetes registry of Saxony, Germany

Hormone Research in Paediatrics

Volumn 74, Issue 4, 2010, Pages 285-291

  Galler, Angela ^a,d   Stange, Thoralf ^b   Müller, Gabriele ^b   Näke, Andrea ^b   Vogel, Christian ^c   Kapellen, Thomas ^a   Bartelt, Heike ^a   Kunath, Hildebrand ^b   Koch, Rainer ^b   Kiess, Wieland ^a   Rothe, Ulrike ^b  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c KLINIKUM CHEMNITZ   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Diabetes incidence; Epidemiology; Ketoacidosis; Type 1 diabetes

Indexed keywords

ADOLESCENT; ARTICLE; BLOOD PH; CHILD; CHILDHOOD DISEASE; DIABETES MELLITUS; FAMILY HISTORY; FEMALE; GERMANY; HUMAN; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; KETOACIDOSIS; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; MATURITY ONSET DIABETES MELLITUS; NEWBORN; NON INSULIN DEPENDENT DIABETES MELLITUS; PRESCHOOL CHILD; PRIORITY JOURNAL; PUBLIC HEALTH; SCHOOL CHILD; UNCONSCIOUSNESS;

ADOLESCENT; AGE OF ONSET; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; FAMILY HEALTH; GERMANY; HUMANS; HYDROGEN-ION CONCENTRATION; INCIDENCE; INFANT; KETOSIS; MALE; MASS SCREENING; PUBLIC HEALTH PRACTICE; REGISTRIES; SEASONS; TIME FACTORS; UNCONSCIOUSNESS;

EID: 77958077957     PISSN: 16632818     EISSN: 16632826     Source Type: Journal    
DOI: 10.1159/000303141     Document Type: Article

References (34)

1. Aamodt G, Stene LC, Njølstad PR, et al; the Norwegian Childhood Diabetes Study Group: Spatiotemporal trends and age-period- cohort modeling of the incidence of type diabetes among children aged ! 15 years in Norway 1973-1982 and 1989-2003. Diabetes Care 2007; 30: 884-889.
2. Harjutsalo V, Sjöberg L, Tuomilehto J: Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study. Lancet 2007; 371: 1777-1782.
3. International Diabetes Federation: Diabetes in children epidemiology. Pediatr Diabetes 2007; 8: 10-18.
4. Karvonen M, Viik-Kajander M, Moltchanova E, et al, for the Diabetes Mondiale Project Group: Incidence of childhood diabetes type 1 worldwide. Diabetes Care 2000; 23: 1516-1526.
5. Onkamo P, Väänänen S, Karvonen M, Tuomilehto J: Worldwide increase in incidence of type 1 diabetes - the analysis of the data on published incidence trends. Diabetologia 1999; 42: 1395-1403.
6. Soltész G: Diabetes in the young: a paediatric and epidemiological perspective. Diabetologia 2003; 46: 447-454.
7. Soltesz G, Patterson CC, Dahlquist G, Eurodiab Study Group: Worldwide childhood type 1 diabetes incidence - what can we learn from epidemiology? Pediatr Diabetes 2007; 8: 6-14.
8. Carle F, Gesuita R, Bruno G, et al; for the RIDI Study Group: Diabetes incidence in 0- to 14-year age-group in Italy. Diabetes Care 2004; 27: 2790-2797.
9. Eurodiab ACE Study Group: Variation and trends in incidence of childhood diabetes in Europe. Lancet 2000; 355: 873-876.
10. Newhook LA, Curtis J, Hagerty D, et al: High incidence of childhood type 1 diabetes in the Avalon Peninsula, Newfoundland, Canada. Diabetes Care 2004; 27: 885-888.
11. Tuomilehto J, Karvonen M, Pitkäniemi J, et al; and the Finnish Childhood Type 1 Diabetes Registry Group: Record-high incidence of type 1 (insulin-dependent) diabetes mellitus in Finnish children. Diabetologia 1999; 42: 655-660. (Pubitemid 29265582)
12. Neu A, Kehrer M, Hub R, Ranke B: Incidence of IDDM in German children aged 0-14 years. A 6-year population-based study (1987-1993). Diabetes Care 1997; 20: 530-533.
13. Neu A, Ehehalt S, Willasch A, et al: Rising incidence of type 1 diabetes in Germany. 12- year trend analysis in children 0-14 years of age. Diabetes Care 2001; 24: 785-786.
14. Patterson CC, Dahlquist GG, Gyürüs E, Green A, Soltesz G, and the Eurodiab Study Group: Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-2020: a multicentre prospective registration study. Lancet 2009; 373: 2027-2033.
15. Michaelis D, Jutzi E, Heinke P: 30jährige Inzidenz- und Prävalenztrend des juvenilen Typ 1 Diabetes in der ostdeutschen Bevölkerung. Diab Stoffw 1993; 2: 245-250.
16. Craig ME, Hattersley A, Donaghue K: International Society for Pediatric and Adolescent Diabetes. ISPAD Clinical Practice Consensus Guidelines 2006-2007. Definition, epidemiology and classification. Pediatr Diabetes 2006; 7: 343-351.
17. Hattersley AT: Heterogeneity in type 2 diabetes: lessons from maturity-onset diabetes of the young. Diabetic Rev Int 1998; 15: 15-24.
18. Ledermann HM: Is maturity-onset diabetes at young age (MODY) more common in Europe than previously assumed? Lancet 1995; 345: 648.
19. Lehto M, Wipemo C, Ivarsson SA, et al: High frequency of mutations in MODY and mitochondrial genes in Scandinavian patients with familial early-onset diabetes. Diabetologia 1999; 42: 1131-1137.
20. Wolfsdorf J, Craig ME, Daneman D, Dunger D, Edge J, Lee WRW, Rosenbloom A, Sperling MA, Hanas R: ISPAD Clinical Practice Consensus Guidelines 2006-2007. Diabetic ketoacidosis. Pediatr Diabetes 2007; 8: 28-42.
21. Bruno G, LaPorte RE, Merletti F, et al: National diabetes programs. Application of capture-recapture to count diabetes? Diabetes Care 1994; 17: 548-556.
22. WHO 2009. www.gbe-bund.de
23. Ehehalt S, Blumenstock G, Willasch AM, et al; DIARY Study Group Baden-Württemberg: Continuous rise in incidence of childhood type 1 diabetes in Germany. Diabet Med 2008; 25: 755-757.
24. Songini M, Casu A: Epidemiology of childhood diabetes. Acta Biomed 2005; 76: 19-25.
25. Svensson J, Carstensen B, Mortensen HB, Borch-Johnsen K, Danish Study Group of Childhood Diabetes: Early childhood risk factors associated with type 1 diabetes - is gender important? Eur J Epidemiol 2005; 20: 429-434.
26. Fagot-Campagna A, Saaddine JB, Flegal KM, Beckles GL: Third National Health and Nutrition Examination Survey. Diabetes, impaired fasting glucose, and elevated HbA1c in US adolescents: the Third National Health and Nutrition Examination Survey. Diabetes Care 2001; 24: 834-837.
27. Kalies H, Lenz J, von Kries R: Prevalence of overweight and obesity and trends in body mass index in German pre-school children, 1982-1997. Int J Obes Relat Metab Disord 2002; 26: 1211-1217.
28. Velho G, Froguel P: Genetic, metabolic and clinical characteristics of maturity-onset diabetes of the young. Eur J Endocrinol 1998; 138: 233-239.
29. Raine JE, Donaldson MDC, Savage MO, Hintz RL: Practical Endocrinology and Diabetes in Children, ed 2. Malden/MA, Blackwell, 2006.
30. Rewers A, Klingensmith G, Davis C, et al: Diabetic ketoacidosis at onset of diabetes: the SEARCH for Diabetes in Youth Study. Diabetes 2005; 54:A63.
31. Vanelli M, Chiari G, Ghizzoni L: Effectiveness of a prevention program for diabetic ketoacidosis in children. Diabetes Care 1999; 22: 7-9.
32. Vanelli M, Scarabello C, Fainardi V: Available tools for primary ketoacidosis prevention at diabetes diagnosis in children and adolescents. 'The Parma campaign'. Acta Biomed 2008; 79: 73-78.
33. Neu A, Willasch A, Ehehalt S, Hub R, Ranke MB; DIARY Study Group Baden-Wuerttemberg: Ketoacidosis at onset of type 1 diabetes mellitus in children - frequency and clinical presentation. Pediatr Diabetes 2003; 4: 77-81.
34. Pinkey JH, Bingley PJ, Sawtell PA, Dunger DB, Gale EA: Presentation and progress of childhood diabetes mellitus: a prospective population based study. Diabetologia 1994; 37: 70-74.