Comparison of haematology, coagulation and clinical chemistry parameters in blood samples from the sublingual vein and vena cava in Sprague-Dawley rats

Laboratory Animals

Volumn 44, Issue 4, 2010, Pages 344-351

  Seibel, J ^a   Bodié, Karen ^a   Weber, S ^a   Bury, D ^a   Kron, M ^a   Blaich, G ^a  

^a ABBOTT GMBH AND CO KG   (Germany)

Author keywords

Blood sampling; Equivalence; Refinement; Sublingual vein; Vena cava

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CALCIUM; HEMOGLOBIN; ISOFLURANE; NITROGEN; UREA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANESTHESIA INDUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOPSY; BASOPHIL; BLOOD CLOTTING; BLOOD SAMPLING; CALCIUM BLOOD LEVEL; CAVA VEIN; CELLULAR DISTRIBUTION; CLINICAL CHEMISTRY; CONTROLLED STUDY; DRUG SAFETY; EOSINOPHIL; ERYTHROCYTE; HEMATOCRIT; HEMATOLOGY; INFERIOR CAVA VEIN; LEUKOCYTE; LEUKOCYTE COUNT; LYMPHOCYTE; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MONOCYTE; NEUTROPHIL; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PATHOLOGY; PROTHROMBIN TIME; RAT; RETICULOCYTE COUNT; SPRAGUE DAWLEY RAT; STRESS; SUBLINGUAL VEIN; THROMBOCYTE COUNT; THROMBOCYTE VOLUME; TONGUE; UREA NITROGEN BLOOD LEVEL; VEIN PUNCTURE;

ANIMALS; BLOOD SPECIMEN COLLECTION; CLINICAL CHEMISTRY TESTS; HEMATOLOGIC TESTS; LABORATORY ANIMAL SCIENCE; MALE; RATS; RATS, SPRAGUE-DAWLEY; STRESS, PHYSIOLOGICAL; TONGUE; VENA CAVA, INFERIOR;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 77958064339     PISSN: 00236772     EISSN: None     Source Type: Journal    
DOI: 10.1258/la.2010.009049     Document Type: Article

References (15)

1. Christensen SD, Mikkelsen LF, Fels JJ, Bodvarsdóttir TB, Hansen AK. Quality of plasma sampled by different methods for multiple blood sampling in mice. Lab Anim 2009;43:65-71
2. Heimann M, Käsermann HP, Pfister R, Roth DR, Bürki K. Blood collection from the sublingual vein in mice and hamsters: a suitable alternative to retrobulbar technique that provides large volumes and minimizes tissue damage. Lab Anim 2009;43:255-60
3. Toft MF, Petersen MH, Dragsted N, Hansen AK. The impact of different blood sampling methods on laboratory rats under different types of anaesthesia. Lab Anim 2006;40:261-74 (Pubitemid 44065223)
4. Diehl KH, Hull R, Morton D, et al. European Federation of Pharmaceutical Industries Association and European Centre for the Validation of Alternative Methods. A good practice guide to the administration of substances and removal of blood, including routes and volumes. J Appl Toxicol 2001;21:15-23
5. First report of the BVA/FRAME/RSPCA/UFAW Joint Working Group on Refinement. Removal of blood from laboratory mammals and birds. Lab Anim 1993;27:1-22
6. Krinke A, Kobel W, Krinke G. Does the repeated orbital sinus puncture alter the occurrence of changes with age in the retina, the lens, or the Harderian gland of laboratory rats? Z Versuchstierkd 1988;31:111-19
7. Everitt BS. The Cambridge Dictionary of Statistics. 2nd edn. Cambridge: Cambridge University Press, 2002
8. Wellek S. Testing Statistical Hypotheses of Equivalence. Boca Raton: Chapman & Hall/CRC, 2003
9. Hollander M, Wolfe DA. Nonparametric Statistical Methods. 2nd edn. New York: Wiley-Interscience, 1999
10. Mahl A, Heining P, Ulrich P, et al. Comparison of clinical pathology parameters with two different blood sampling techniques in rats: retrobulbar plexus versus sublingual vein. Lab Anim 2000;34:351-61
11. Matsuzawa T, Tabata H, Sakazume M, Yoshida S, Nakamura A. A comparison of the effect of bleeding site on haematological and plasma chemistry values of F344 rats: the inferior vena cava, abdominal aorta and orbital venous plexus. Comp Haematol Int 1994;4:207-11
12. Dameron GW, Weingand KW, Duderstadt JM, et al. Effect of bleeding site on clinical laboratory testing of rats: orbital venous plexus versus posterior vena cava. Lab Anim Sci 1992;42:299-301
13. Smith CN, Neptun DA, Irons RD. Effect of sampling site and collection method on variations in baseline clinical pathology parameters in Fischer-344 rats. II. Clinical hematology. Fundam Appl Toxicol 1986;7:658-63
14. Neptun DA, Smith CN, Irons RD. Effect of sampling site and collection method on variations in baseline clinical pathology parameters in Fischer-344 rats. 1. Clinical chemistry. Fundam Appl Toxicol 1985;5:1180-5
15. Salemink PJM, Korsten J, de Leeuw P. Prothrombin times and activated partial thromboplastin times in toxicology: a comparison of different blood withdrawal sites for Wistar rats. Comp Haematol Int 1994;4:173-6 (Pubitemid 24295400)