Effects of EGb combined with ED on hematology in cerebral ischemia reperfusion injury in rats with Qi deficiency and blood stasis

Chinese Pharmacological Bulletin

Volumn 26, Issue 8, 2010, Pages 1049-1053

  Hou, Xi ^a   Liang, Feng ^a   Li, Ai Jian ^a   Wang, Can ^a   Hou, Xiao Yu ^b   Dai, Ti Jun ^b   Gui, Chang Qing ^c  

^a Anhui College of Chinese Traditional Medicine   (China)

^b XUZHOU MEDICAL UNIVERSITY   (China)

^c WANNAN MEDICAL COLLEGE   (China)

Author keywords

Cerebral ischemia reperfusion; ED; EGb; Hematology; Qi deficiency and blood stasis; Rat

Indexed keywords

GINKGO BILOBA EXTRACT; HEMOGLOBIN; NORPHENAZONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY MASS; BRAIN ARTERY; BRAIN ISCHEMIA; COMBINATION CHEMOTHERAPY; DRUG EFFECT; ERYTHROCYTE COUNT; ERYTHROCYTE SEDIMENTATION RATE; FATIGUE; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HEMOSTASIS; HISTOPATHOLOGY; HUNGER; INFLAMMATION; LEUKOCYTE COUNT; LIPID DIET; MINIMAL BRAIN DYSFUNCTION; NERVE CELL LESION; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; RAT; REPERFUSION; REPERFUSION INJURY; SUTURE;

EID: 77958055102     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Margaill I Plokine M. Lemuel D. Antioxidant strategies in the treatment of stroke[J]. Free Rad Biol Med, 2005,39:429.
2. Wang J, Zao H, Li J, et al. Experimental study on multilateral establishment of animal model of the Qi - deficiency and blood stasis syndrome of cerebral ischemia in rat[J]. Acta Lab Animal Sci Sin, 2001,9(4):216-20.
3. Long E Z, Weinstein P R, Carlson S, et al. Reversible middle cerebral artery occlusion without craniotomy in rats[J]. Stroke, 1989,20(1):84-91.
4. Li J, Wang J. Evaluation on improvement of biological features by method of Yiqi Huoxue in reperfused local cerebral ischemia mice with Qi deficiency and blood stasis[J]. Chin J Basic Med Tradit Chin Med, 2003,9(4):22-4.
5. Li J, Wang J, Hu J P, et al. Effects of Yiqi Huoxue method on nitric oxide and neurocyte apoptosis in reperfusion injury rats with cerebral ischemia[J]. Chin J Basic Med Tradit Chin Med, 2007,13(12):898-900.
6. Ma Y L. Curative effect of Edaravone combined with ginkgo leaf in injection[J]. Chin J Clin Rat Drug Use, 2009,2(15):61.
7. Zang Y Y, Liu Y, Fu S T. Cerebral ischemic damage and inflammatory reaction[J]. Chin Pharmacol Bull, 2006,22(1):602-5.
8. Ito K, Ozasa H, Horikawa S. Edaravone protects against lung injury induced by intestinal ischemia/reperfusion in rat[J]. Free Radic Biol Med, 2005,38(3):369-74.
9. Li H, Liu K X, Feng J L, et al. Effects of ginkgo biloba extra on expression of P-selectin and myeloperoxidase activity following cerebral ischemia reperfusion injury in rats[J]. J Clin Neurol, 2007,20(6):435-7.
10. Guo F, Zhao S, Huang H L, et al. Effects of Xinghuayu parenteral solution on hemodynamics and blood coagulation[J]. Chin Pharmacol Bull, 2005,21(5):602-5.
11. Huang JY, Sun J N, Mei S C, et al. Protective effects of ginkgolide B on cerebral ischemia reperfusion injury in rats[J]. Chin Pharmacol Bull, 2008,24(2):269-72.