Cardiac function is not significantly diminished in hearts isolated from young caveolin-1 knockout mice

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 299, Issue 4, 2010, Pages

  Chow, Ava K ^a   Daniel, Edwin E ^a   Schulz, Richard ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Isolated hearts; Matrix metalloproteinase 2

Indexed keywords

ALPHA ACTININ; CAVEOLIN 1; GELATINASE A; ISOPRENALINE; TROPONIN I;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; ENZYME ACTIVITY; HEART FUNCTION; HEART PRELOAD; HEART RATE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; SYSTOLIC BLOOD PRESSURE; WESTERN BLOTTING;

ACTININ; ANIMALS; CARDIAC OUTPUT; CARDIOTONIC AGENTS; CAVEOLIN 1; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART; HEART RATE; ISOPROTERENOL; MALE; MATRIX METALLOPROTEINASE 2; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; MYOCARDIUM; TROPONIN I;

EID: 77958033452     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01195.2009     Document Type: Article

References (29)

1. Ballard-Croft C, Locklar AC, Kristo G, Lasley RD. Regional myocardial ischemia-induced activation of MAPKs is associated with subcellular redistribution of caveolin and cholesterol. Am J Physiol Heart Circ Physiol 291: H658-H667, 2006. (Pubitemid 44175071)
2. Bergman MR, Teerlink JR, Mahimkar R, Li L, Zhu BQ, Nguyen A, Dahi S, Karliner JS, Lovett DH. Cardiac matrix metalloproteinase-2 expression independently induces marked ventricular remodeling and systolic dysfunction. Am J Physiol Heart Circ Physiol 292: H1847-H1860, 2007. (Pubitemid 46572408)
3. Bernatchez PN, Bauer PM, Yu J, Prendergast JS, He P, Sessa WC. Dissecting the molecular control of endothelial NO synthase by caveolin-1 using cell-permeable peptides. Proc Natl Acad Sci USA 102: 761-766, 2005. (Pubitemid 40282739)
4. Cho WJ, Chow AK, Schulz R, Daniel EE. Matrix metalloproteinase-2, caveolins, focal adhesion kinase and c-Kit in cells of the mouse myocardium. J Cell Mol Med 11: 1069-1086, 2007. (Pubitemid 350037049)
5. Chow AK, Cena J, El-Yazbi AF, Crawford BD, Holt A, Cho WJ, Daniel EE, Schulz R. Caveolin-1 inhibits matrix metalloproteinase-2 activity in the heart. J Mol Cell Cardiol 42: 896-901, 2007. (Pubitemid 46527597)
6. Cohen AW, Park DS, Woodman SE, Williams TM, Chandra M, Shirani J, Pereira de SA, Kitsis RN, Russell RG, Weiss LM, Tang B, Jelicks LA, Factor SM, Shtutin V, Tanowitz HB, Lisanti MP. Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts. Am J Physiol Cell Physiol 284: C457-C474, 2003. (Pubitemid 36120083)
7. El Yazbi AF, Cho WJ, Schulz R, Daniel EE. Caveolin-1 knockout alters β-adrenoceptors function in mouse small intestine. Am J Physiol Gastrointest Liver Physiol 291: G1020-G1030, 2006. (Pubitemid 44904156)
8. Errami M, Galindo CL, Tassa AT, Dimaio JM, Hill JA, Garner HR. Doxycycline attenuates isoproterenol- and transverse aortic banding-induced cardiac hypertrophy in mice. J Pharmacol Exp Ther 324: 1196-1203, 2008. (Pubitemid 351397830)
9. Feron O, Balligand JL. Caveolins and the regulation of endothelial nitric oxide synthase in the heart. Cardiovasc Res 69: 788-797, 2006. (Pubitemid 43227977)
10. Hare JM, Lofthouse RA, Juang GJ, Colman L, Ricker KM, Kim B, Senzaki H, Cao S, Tunin RS, Kass DA. Contribution of caveolin protein abundance to augmented nitric oxide signaling in conscious dogs with pacing-induced heart failure. Circ Res 86: 1085-1092, 2000. (Pubitemid 30367868)
11. Head BP, Patel HH, Roth DM, Lai NC, Niesman IR, Farquhar MG, Insel PA. G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes. J Biol Chem 280: 31036-31044, 2005.
12. McCawley LJ, Matrisian LM. Matrix metalloproteinases: they're not just for matrix anymore! Curr Opin Cell Biol 13: 534-540, 2001.
13. Murata T, Lin MI, Huang Y, Yu J, Bauer PM, Giordano FJ, Sessa WC. Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice. J Exp Med 204: 2373-2382, 2007. (Pubitemid 47529323)
14. Nagase H, Visse R, Murphy G. Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res 69: 562-573, 2006. (Pubitemid 43139720)
15. Okamoto T, Akaike T, Nagano T, Miyajima S, Suga M, Ando M, Ichimori K, Maeda H. Activation of human neutrophil procollagenase by nitrogen dioxide and peroxynitrite: a novel mechanism for procollagenase activation involving nitric oxide. Arch Biochem Biophys 342: 261-274, 1997. (Pubitemid 27251247)
16. Okamoto T, Akaike T, Sawa T, Miyamoto Y, van der Vliet A, Maeda H. Activation of matrix metalloproteinases by peroxynitrite-induced protein S-glutathiolation via disulfide S-oxide formation. J Biol Chem 276: 29596-29602, 2001.
17. Patel HH, Tsutsumi YM, Head BP, Niesman IR, Jennings M, Horikawa Y, Huang D, Moreno AL, Patel PM, Insel PA, Roth DM. Mechanisms of cardiac protection from ischemia/reperfusion injury: a role for caveolae and caveolin-1. FASEB J 21: 1565-1574, 2007. (Pubitemid 46684858)
18. Puyraimond A, Fridman R, Lemesle M, Arbeille B, Menashi S. MMP-2 colocalizes with caveolae on the surface of endothelial cells. Exp Cell Res 262: 28-36, 2001. (Pubitemid 32989005)
19. Rybin VO, Xu X, Lisanti MP, Steinberg SF. Differential targeting of beta-adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway. J Biol Chem 275: 41447-41457, 2000. (Pubitemid 32054981)
20. Sariahmetoglu M, Crawford BD, Leon H, Sawicka J, Li L, Ballermann BJ, Holmes C, Berthiaume LG, Holt A, Sawicki G, Schulz R. Regulation of matrix metalloproteinase-2 (MMP-2) activity by phosphorylation. FASEB J 21: 2486-2495, 2007. (Pubitemid 47230678)
21. Sasse J, Gallagher SR. Detection of proteins on blot transfer membranes. Curr Protoc Mol Biol Chapter 10: Unit 10.7, 2008.
22. Sawicki G, Leon H, Sawicka J, Sariahmetoglu M, Schulze CJ, Scott PG, Szczesna-Cordary D, Schulz R. Degradation of myosin light chain in isolated rat hearts subjected to ischemia-reperfusion injury: a new intracellular target for matrix metalloproteinase-2. Circulation 112: 544-552, 2005. (Pubitemid 41060795)
23. Schulz R. Intracellular targets of matrix metalloproteinase-2 in cardiac disease: rationale and therapeutic approaches. Annu Rev Pharmacol Toxicol 47: 211-242, 2007.
24. Schwencke C, Okumura S, Yamamoto M, Geng YJ, Ishikawa Y. Colocalization of beta-adrenergic receptors and caveolin within the plasma membrane. J Cell Biochem 75: 64-72, 1999. (Pubitemid 29402545)
25. Sivakumar P, Gupta S, Sarkar S, Sen S. Upregulation of lysyl oxidase and MMPs during cardiac remodeling in human dilated cardiomyopathy. Mol Cell Biochem 307: 159-167, 2008. (Pubitemid 350238658)
26. Sung MM, Schulz CG, Wang W, Sawicki G, Bautista-Lopez NL, Schulz R. Matrix metalloproteinase-2 degrades the cytoskeletal protein alpha-actinin in peroxynitrite mediated myocardial injury. J Mol Cell Cardiol 43: 429-436, 2007. (Pubitemid 47451426)
27. Wang W, Schulze CJ, Suarez-Pinzon WL, Dyck JR, Sawicki G, Schulz R. Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury. Circulation 106: 1543-1549, 2002.
28. Wang W, Viappiani S, Sawicka J, Schulz R. Inhibition of endogenous nitric oxide in the heart enhances matrix metalloproteinase-2 release. Br J Pharmacol 145: 43-49, 2005. (Pubitemid 40675547)
29. Zhao YY, Liu Y, Stan RV, Fan L, Gu Y, Dalton N, Chu PH, Peterson K, Ross J Jr, Chien KR. Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice. Proc Natl Acad Sci USA 99: 11375-11380, 2002. (Pubitemid 34920933)