Solid-phase synthesis and screening of N-acylated polyamine (NAPA) combinatorial libraries for protein binding

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 22, 2010, Pages 6500-6503

  Iera, Jaclyn A ^a   Jenkins, Lisa M Miller ^b   Kajiyama, Hiroshi ^a   Kopp, Jeffrey B ^a   Appella, Daniel H ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Combinatorial library; High throughput screening; Protein protein interactions; Vpr

Indexed keywords

N ACYLATED POLYAMINE; POLYAMINE DERIVATIVE; UNCLASSIFIED DRUG; VPR PROTEIN;

ARTICLE; COMBINATORIAL LIBRARY; ENZYME INHIBITION; POLYAMINE SYNTHESIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SCREENING; SOLID PHASE SYNTHESIS; VIRUS REPLICATION;

ACYLATION; COMBINATORIAL CHEMISTRY TECHNIQUES; POLYAMINES; PROTEIN BINDING;

EID: 77958027411     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.054     Document Type: Article

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