메뉴 건너뛰기




Volumn 299, Issue 4, 2010, Pages

Sildenafil added to sitaxsentan in overcirculation-induced pulmonary arterial hypertension

Author keywords

Combination therapy; Congenital heart disease; Left to right shunt; Right ventricle

Indexed keywords

ANGIOPOIETIN 1; BONE MORPHOGENETIC PROTEIN RECEPTOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; ENDOTHELIN 1; PLACEBO; SILDENAFIL; SITAXSENTAN;

EID: 77958026408     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00418.2010     Document Type: Article
Times cited : (15)

References (32)
  • 1
    • 0037046175 scopus 로고    scopus 로고
    • Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor
    • DOI 10.1161/01.CIR.0000012754.72951.3D
    • Atkinson C, Stewart S, Upton PD, Machado R, Thomson JR, Trembath RC, Morrell NW. Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor. Circulation 105: 1672-1678, 2002. (Pubitemid 34298611)
    • (2002) Circulation , vol.105 , Issue.14 , pp. 1672-1678
    • Atkinson, C.1    Stewart, S.2    Upton, P.D.3    Machado, R.4    Thomson, J.R.5    Trembath, R.C.6    Morrell, N.W.7
  • 3
    • 62149104001 scopus 로고    scopus 로고
    • The right ventricle under pressure: Cellular and molecular mechanisms of right-heart failure in pulmonary hypertension
    • Bogaard HJ, Abe K, Vonk Noordegraaf A, Voelkel NF. The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension. Chest 135: 794-804, 2009.
    • (2009) Chest , vol.135 , pp. 794-804
    • Bogaard, H.J.1    Abe, K.2    Vonk Noordegraaf, A.3    Voelkel, N.F.4
  • 4
    • 27444439573 scopus 로고    scopus 로고
    • Sildenafil inhibits beta-adrenergic-stimulated cardiac contractility in humans
    • DOI 10.1161/CIRCULATIONAHA.105.540500
    • Borlaug BA, Melenovsky V, Marhin T, Fitzgerald P, Kass DA. Sildenafil inhibits beta-adrenergic-stimulated cardiac contractility in humans. Circulation 112: 2642-2649, 2005. (Pubitemid 41532601)
    • (2005) Circulation , vol.112 , Issue.17 , pp. 2642-2649
    • Borlaug, B.A.1    Melenovsky, V.2    Marhin, T.3    Fitzgerald, P.4    Kass, D.A.5
  • 6
    • 70349776690 scopus 로고    scopus 로고
    • Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: State of the art and clinical and research implications
    • Champion HC, Michelakis ED, Hassoun PM. Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: state of the art and clinical and research implications. Circulation 120: 992-1007, 2009.
    • (2009) Circulation , vol.120 , pp. 992-1007
    • Champion, H.C.1    Michelakis, E.D.2    Hassoun, P.M.3
  • 7
    • 33744907723 scopus 로고    scopus 로고
    • Bosentan, sildenafil, and their combination in the monocrotaline model of pulmonary hypertension in rats
    • Clozel M, Hess P, Rey M, Iglarz M, Binkert C, Qiu C. Bosentan, sildenafil and their combination in the monocrotaline model of pulmonary hypertension in rats. Exp Biol Med (Maywood) 231: 967-973, 2006. (Pubitemid 43845561)
    • (2006) Experimental Biology and Medicine , vol.231 , Issue.6 , pp. 967-973
    • Clozel, M.1    Hess, P.2    Rey, M.3    Iglarz, M.4    Binkert, C.5    Qiu, C.6
  • 12
    • 45249119855 scopus 로고    scopus 로고
    • Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): A double-blind, randomised controlled trial
    • DOI 10.1016/S0140-6736(08)60919-8, PII S0140673608609198
    • Galié N, Rubin LJ, Hoeper M, Jansa P, Al-Hiti H, Meyer G, Chiossi E, Kusic-Pajic A, Simonneau G. Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomized controlled trial. Lancet 371: 2093-2100, 2008. (Pubitemid 351902178)
    • (2008) The Lancet , vol.371 , Issue.9630 , pp. 2093-2100
    • Galie, N.1    Rubin, L.2    Hoeper, M.3    Jansa, P.4    Al-Hiti, H.5    Meyer, G.6    Chiossi, E.7    Kusic-Pajic, A.8    Simonneau, G.9
  • 13
    • 70449228209 scopus 로고
    • The pathology of hypertensive pulmonary vascular disease; a description of six grades of structural changes in the pulmonary arteries with special reference to congenital cardiac septal defects
    • Heath D, Edwards JE. The pathology of hypertensive pulmonary vascular disease; a description of six grades of structural changes in the pulmonary arteries with special reference to congenital cardiac septal defects. Circulation 18: 533-547, 1958.
    • (1958) Circulation , vol.18 , pp. 533-547
    • Heath, D.1    Edwards, J.E.2
  • 14
    • 40749090043 scopus 로고    scopus 로고
    • PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation
    • DOI 10.1152/ajplung.00245.2007
    • Hemnes A, Zaiman A, Champion HC. PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation. Am J Physiol Lung Cell Mol Physiol 294: L24-L33, 2008. (Pubitemid 351380315)
    • (2008) American Journal of Physiology - Lung Cellular and Molecular Physiology , vol.294 , Issue.1
    • Hemnes, A.R.1    Zaiman, A.2    Champion, H.C.3
  • 16
    • 20844453067 scopus 로고    scopus 로고
    • Magnetic resonance imaging analysis of right ventricular pressure-volume loops: In vivo validation and clinical application in patients with pulmonary hypertension
    • DOI 10.1161/01.CIR.0000143138.02493.DD
    • Kuehne T, Yilmaz S, Steendijk P, Moore P, Groenink M, Saaed M, Weber O, Higgins CB, Ewert P, Fleck E, Nagel E, Schulze-Neick I, Lange P. Magnetic resonance imaging analysis of right ventricular pressure- volume loops: in vivo validation and clinical application in patients with pulmonary hypertension. Circulation 110: 2010-2016, 2004. (Pubitemid 39331915)
    • (2004) Circulation , vol.110 , Issue.14 , pp. 2010-2016
    • Kuehne, T.1    Yilmaz, S.2    Steendijk, P.3    Moore, P.4    Groenink, M.5    Saaed, M.6    Weber, O.7    Higgins, C.B.8    Ewert, P.9    Fleck, E.10    Nagel, E.11    Schulze-Neick, I.12    Lange, P.13
  • 23
    • 0018403724 scopus 로고
    • Aorta-pulmonary shunts in growing pigs. Functional and structural assessment of the changes in the pulmonary circulation
    • Rendas A, Lennox S, Reid L. Aorta-pulmonary shunts in growing pigs. Functional and structural assessment of the changes in the pulmonary circulation. J Thorac Cardiovasc Surg 77: 109-118, 1979. (Pubitemid 9103560)
    • (1979) Journal of Thoracic and Cardiovascular Surgery , vol.77 , Issue.1 , pp. 109-118
    • Rendas, A.1    Lennox, S.2    Reid, L.3
  • 31
    • 0033562350 scopus 로고    scopus 로고
    • Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
    • DOI 10.1006/abio.1999.4085
    • Winer J, Jung CK, Shackel I, Williams PM. Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 270: 41-49, 1999. (Pubitemid 29230718)
    • (1999) Analytical Biochemistry , vol.270 , Issue.1 , pp. 41-49
    • Winer, J.1    Jung, C.K.S.2    Shackel, I.3    Williams, P.M.4
  • 32
    • 45149132191 scopus 로고    scopus 로고
    • Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: Implications for familial pulmonary arterial hypertension
    • Yang J, Davies RJ, Southwood M, Long L, Yang X, Sobolewski A, Upton PD, Trembath RC, Morrell NW. Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension. Circ Res 102: 1212-1221, 2008.
    • (2008) Circ Res , vol.102 , pp. 1212-1221
    • Yang, J.1    Davies, R.J.2    Southwood, M.3    Long, L.4    Yang, X.5    Sobolewski, A.6    Upton, P.D.7    Trembath, R.C.8    Morrell, N.W.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.