Stratifying patients with stroke in trials that target brain repair

Stroke

Volumn 41, Issue 10 SUPPL. 1, 2010, Pages

  Cramer, Steven C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

recovery; repair; stratify; stroke; treatment

Indexed keywords

BEHAVIOR; BRAIN INJURY; CONFERENCE PAPER; CONVALESCENCE; DISABILITY; FUNCTIONAL ASSESSMENT; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; PATIENT SELECTION; PRIORITY JOURNAL; STROKE; TREATMENT INDICATION; TREATMENT OUTCOME; BRAIN; CLINICAL TRIAL (TOPIC); METHODOLOGY; PATHOPHYSIOLOGY;

BRAIN; CLINICAL TRIALS AS TOPIC; HUMANS; PATIENT SELECTION; RECOVERY OF FUNCTION; RESEARCH DESIGN; STROKE;

EID: 77958009437     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.110.595165     Document Type: Conference Paper

References (32)

1. Carmichael ST, Archibeque I, Luke L, Nolan T, Momiy J, Li S. Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortex. Exp Neurol. 2005;193:291-311.
2. Wieloch T, Nikolich K. Mechanisms of neural plasticity following brain injury. Curr Opin Neurobiol. 2006;16:258-264.
3. Duncan P, Zorowitz R, Bates B, Choi J, Glasberg J, Graham G, Katz R, Lamberty K, Reker D. Management of adult stroke rehabilitation care: a clinical practice guideline. Stroke. 2005;36:e100-e143.
4. Cramer SC. Repairing the human brain after stroke. II. Restorative therapies. Ann Neurol. 2008;63:549-560.
5. Wolf SL, Winstein CJ, Miller JP, Taub E, Uswatte G, Morris D, Giuliani C, Light KE, Nichols-Larsen D. Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE randomized clinical trial. JAMA. 2006;296:2095-2104.
6. Lo AC, Guarino PD, Richards LG, Haselkorn JK, Wittenberg GF, Federman DG, Ringer RJ, Wagner TH, Krebs HI, Volpe BT, Bever CT Jr, Bravata DM, Duncan PW, Corn BH, Maffucci AD, Nadeau SE, Conroy SS, Powell JM, Huang GD, Peduzzi P. Robot-assisted therapy for long-term upper-limb impairment after stroke. N Engl J Med. 2010;362:1772-1783.
7. Lanktree MB, Dichgans M, Hegele RA. Advances in genomic analysis of stroke: what have we learned and where are we headed? Stroke. 2010;41:825-832.
8. Cramer SC, Fitzpatrick C, Warren M, Hill MD, Brown D, Whitaker L, Ryckborst KJ, Plon L. The beta-hcg + erythropoietin in acute stroke (BETAS) study: a 3-center, single-dose, open-label, noncontrolled, phase IIa safety trial. Stroke. 2010;41:927-931.
9. Gladstone DJ, Danells CJ, Armesto A, McIlroy WE, Staines WR, Graham SJ, Herrmann N, Szalai JP, Black SE. Physiotherapy coupled with dex-troamphetamine for rehabilitation after hemiparetic stroke: a randomized, double-blind, placebo-controlled trial. Stroke. 2006;37:179-185.
10. Shan K, Nagueh SF, Zoghbi WA. Assessment of myocardial viability with stress echocardiography. Cardiol Clin. 1999;17:539 -553, ix
11. Radpour R, Barekati Z, Kohler C, Holzgreve W, Zhong XY. New trends in molecular biomarker discovery for breast cancer. Genet Test Mol Biomarkers. 2009;13:565-571.
12. Cramer SC, Koroshetz WJ, Finklestein SP. The case for modality-specific outcome measures in clinical trials of stroke recovery-promoting agents. Stroke. 2007;38:1393-1395.
13. Nijland RH, van Wegen EE, Harmeling-van der Wel BC, Kwakkel G. Presence of finger extension and shoulder abduction within 72 hours after stroke predicts functional recovery: early prediction of functional outcome after stroke: The EPOS cohort study. Stroke. 2010;41:745-750.
14. Crafton K, Mark A, Cramer S. Improved understanding of cortical injury by incorporating measures of functional anatomy. Brain. 2003;126:1650-1659.
15. Schaechter JD, Moore CI, Connell BD, Rosen BR, Dijkhuizen RM. Structural and functional plasticity in the somatosensory cortex of chronic stroke patients. Brain. 2006;129:2722-2733.
16. Lindenberg R, Renga V, Zhu LL, Betzler F, Alsop D, Schlaug G. Structural integrity of corticospinal motor fibers predicts motor impairment in chronic stroke. Neurology. 2010;74:280-287.
17. Cramer SC, Parrish TB, Levy RM, Stebbins GT, Ruland SD, Lowry DW, Trouard TP, Squire SW, Weinand ME, Savage CR, Wilkinson SB, Juranek J, Leu SY, Himes DM. Predicting functional gains in a stroke trial. Stroke. 2007;38:2108-2114.
18. Stinear CM, Barber PA, Smale PR, Coxon JP, Fleming MK, Byblow WD. Functional potential in chronic stroke patients depends on corticospinal tract integrity. Brain. 2007;130:170-180.
19. Dong Y, Dobkin BH, Cen SY, Wu AD, Winstein CJ. Motor cortex activation during treatment may predict therapeutic gains in paretic hand function after stroke. Stroke. 2006;37:1552-1555.
20. Koski L, Mernar T, Dobkin B. Immediate and long-term changes in corticomotor output in response to rehabilitation: correlation with functional improvements in chronic stroke. Neurorehabil Neural Repair. 2004;18:230-249.
21. Dromerick AW, Edwards DF, Diringer MN. Sensitivity to changes in disability after stroke: a comparison of four scales useful in clinical trials. J Rehabil Res Dev. 2003;40:1-8.
22. Lai SM, Duncan PW, Keighley J, Johnson D. Depressive symptoms and independence in badl and iadl. J Rehabil Res Dev. 2002;39:589-596.
23. Baron J, Cohen L, Cramer S, Dobkin B, Johansen-Berg H, Loubinoux I, Marshall R, Ward NS. Neuroimaging in stroke recovery: a position paper from the first international workshop on neuroimaging and stroke recovery. Cerebrovasc Dis. 2004;18:260-267.
24. Calautti C, Naccarato M, Jones PS, Sharma N, Day DD, Carpenter AT, Bullmore ET, Warburton EA, Baron JC. The relationship between motor deficit and hemisphere activation balance after stroke: a 3T fMRI study. Neuroimage. 2007;34:322-331.
25. Grefkes C, Nowak DA, Eickhoff SB, Dafotakis M, Kust J, Karbe H, Fink GR. Cortical connectivity after subcortical stroke assessed with functional magnetic resonance imaging. Ann Neurol. 2008;63:236-246.
26. James GA, Lu ZL, VanMeter JW, Sathian K, Hu XP, Butler AJ. Changes in resting state effective connectivity in the motor network following rehabilitation of upper extremity poststroke paresis. Top Stroke Rehabil. 2009;16:270-281.
27. Cappa S, Perani D, Grassi F, Bressi S, Alberoni M, Franceschi M, Bettinardi V, Todde S, Fazio F. A PET follow-up study of recovery after stroke in acute aphasics. Brain Lang. 1997;56:55-67.
28. Pendlebury S, Blamire A, Lee M, Styles P, Matthews P. Axonal injury in the internal capsule correlates with motor impairment after stroke. Stroke. 1999;30:956-962.
29. Schaechter JD, Fricker ZP, Perdue KL, Helmer KG, Vangel MG, Greve DN, Makris N. Microstructural status of ipsilesional and contralesional corticospinal tract correlates with motor skill in chronic stroke patients. Hum Brain Mapp. 2009;30:3461-3474.
30. Talelli P, Greenwood RJ, Rothwell JC. Arm function after stroke: neu-rophysiological correlates and recovery mechanisms assessed by trans-cranial magnetic stimulation. Clin Neurophysiol. 2006;117:1641-1659.
31. Hensel S, Rockstroh B, Berg P, Elbert T, Schonle P. Left-hemispheric abnormal EEG activity in relation to impairment and recovery in aphasic patients. Psychophysiology. 2004;41:394-400.
32. Siironen J, Juvela S, Kanarek K, Vilkki J, Hernesniemi J, Lappalainen J. The met allele of the bdnf val66met polymorphism predicts poor outcome among survivors of aneurysmal subarachnoid hemorrhage. Stroke. 2007; 38:2858-2860.