Role of supraspinal and spinal α1-adrenergic receptor subtypes in micturition reflex in conscious rats

American Journal of Physiology - Renal Physiology

Volumn 299, Issue 4, 2010, Pages

  Yoshizumi, Masaru ^a   Matsumoto Miyai, Kazumasa ^a   Yonezawa, Akihiko ^b   Kawatani, Masahito ^a  

^a AKITA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

BMY 7378; Cystometrogram; Intracerebroventricular and intrathecal injections; Silodosin; Tamsulosin

Indexed keywords

8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; MESSENGER RNA; SILODOSIN; TAMSULOSIN; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; INDOLE DERIVATIVE; SULFONAMIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER; BLADDER CONTRACTION; BRAIN; BRAIN STEM; CONSCIOUSNESS; CONTROLLED STUDY; CYSTOMETRY; DOSE RESPONSE; DRUG INFUSION; EFFERENT NERVE; FEMALE; LUMBOSACRAL PLEXUS; MESENCEPHALON; MICTURITION; MICTURITION REFLEX; NONHUMAN; PONS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NERVE; SPINAL CORD; ANIMAL; ANIMAL MODEL; DRUG EFFECTS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRASPINAL DRUG ADMINISTRATION; PHYSIOLOGY; REFLEX; WISTAR RAT;

ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; BRAIN; CONSCIOUSNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INDOLES; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SPINAL; MODELS, ANIMAL; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; REFLEX; SPINAL CORD; SULFONAMIDES; URINATION;

EID: 77958006380     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00553.2009     Document Type: Article

References (28)

1. Andersson KE, Wyllie MG. Ejaculatory dysfunction: why all alpha-blockers are not equal. BJU Int 92: 876-877, 2003. (Pubitemid 37548255)
2. Dahlström A, Fuxe K. The distribution of monoamine terminals in the central nervous system. II. Experimentally induced changes in the interneuronal amine levels of the bulbospinal neuron systems. Acta Physiol Scand 274: 1-36, 1965.
3. 1d-adrenergic receptor mRNA in the rat brain and spinal cord. J Chem Neuroanat 13: 115-139, 1997.
4. De Groat WC. Anatomy of the central neural pathways controlling the lower urinary tract. Eur Urol 34, Suppl 1: 2-5, 1998.
5. Elam M, Thorén P, Svensson TH. Locus coeruleus neurons and sympathetic nerves: activation by visceral afferents. Brain Res 375: 117-125, 1986. (Pubitemid 16095372)
6. Gjone R. Excitatory and inhibitory bladder responses to stimulation of 'limbic', diencephalic and mesencephalic structures in the cat. Acta Physiol Scand 66: 91-102, 1966.
7. Gjone R, Setekleiv J. Excitatory and inhibitory bladder responses to stimulation of the cerebral cortex in the cat. Acta Physiol Scand 59: 337-348, 1963.
8. Gu BJ, Ishizuka O, Igawa Y, Nishizawa O, Andersson KE. Role of supraspinal α1-adrenoceptors for voiding in conscious rats with and without bladder outlet obstruction. J Urol 67: 1887-1891, 2002.
9. 2- adrenoceptors on bladder activity induced by bladder distension in anaesthetized rat. BJU Int 85: 925-931, 2000.
10. Lewin RJ, Dillard GV, Porter RW. Extrapyramidal inhibition of the urinary bladder. Brain Res 4: 301-307, 1967.
11. 1A receptors in detrusor over activity associated with partial bladder outlet obstruction in female rats. Eur J Pharmacol 561: 189-193, 2007.
12. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. New York: Academic, 1998.
13. Rickenbacher E, Baez MA, Hale L, Leiser SC, Zderic SA, Valentino RJ. Impact of overactive bladder on the brain: central sequelae of a visceral pathology. Proc Natl Acad Sci USA 105: 10589-10594, 2008.
14. Satoh K, Shimizu N, Tohyama M, Maeda T. Localization of the micturition reflex center at dorsolateral pontine tegmentum of the rat. Neurosci Lett 8: 27-33, 1978. (Pubitemid 8354844)
15. Satoh K, Tohyama M, Sakumoto T, Yamamoto K, Shimizu N. Descending projection of the nucleus tegmentalis laterodorsalis to the spinal cord: studied by the horseradish peroxidase method following 6-hydroxydopa administration. Neurosci Lett 8: 9-15, 1978. (Pubitemid 8354841)
16. Sugaya K, Nishijima S, Miyazato M, Ashitomi K, Hatano T, Ogawa Y. Effects of intrathecal injection of tamsulosin and naftopidil, alpha-1A and -1D adrenergic receptor antagonists, on bladder activity in rats. Neurosci Lett 328: 74-76, 2002. (Pubitemid 34786047)
17. Sugaya K, Ogawa Y, Hatano T, Koyama Y, Miyazato T, Oda M. Evidence for involvement of the subcoeruleus nucleus and nucleus raphe magnus in urine storage and penile erection in decerebrate rats. J Urol 159: 2172-2176, 1998. (Pubitemid 29190801)
18. Swanson LW. Brain Maps: Structure of the Rat Brain: Elsevier, 1992.
19. Tatemichi S, Tomiyama Y, Maruyama I, Kobayashi S, Kobayashi K, Maezawa A, Kobayashi M, Yamazaki Y, Shibata N. Uroselectivity in male dogs of silodosin (KMD-3213), a novel drug for the obstructive component of benign prostatic hyperplasia. Neurourol Urodyn 25: 792-799, 2006. (Pubitemid 44691386)
20. Tohyama M, Satoh K, Sakumoto T, Kimoto Y, Takahashi Y, Yamamoto K, Itakura T. Organization and projections of the neurons in the dorsal tegmental area of the rat. J Hirnforsch 19: 165-176, 1978.
21. 1-adrenoceptor subtypes in rat spinal cord. Eur J Pharmacol 312: 263-266, 1996.
22. Watanabe C, Okuda K, Sakurada C, Ando R, Sakurada T, Sakurada S. Evidence that nitric oxide-glutamate cascade modulates spinal antinociceptive effect of morphine: a behavioural and microdialysis study in rats. Brain Res 990: 77-86, 2003a. (Pubitemid 37244064)
23. Watanabe C, Sakurada T, Okuda K, Sakurada C, Ando R, Sakurada S. The role of spinal nitric oxide and glutamate in nociceptive behaviour evoked by high-dose intrathecal morphine in rats. Pain 106: 269-283, 2003b. (Pubitemid 37505875)
24. Yoshimura N, Sasa M, Ohno Y, Yoshida O, Takaori S. Contraction of urinary bladder by central norepinephrine originating in the locus coeruleus. J Urol 139: 423-427, 1988. (Pubitemid 18059643)
25. Yoshimura N, Sasa M, Yoshida O, Takaori S. Mediation of micturition reflex by central norepinephrine from the locus coeruleus in the cat. J Urol 143: 840-843, 1990.
26. 1-adrenoceptor subtypes in the bladder reflex in anesthetized rats. Am J Physiol Regul Integr Comp Physiol 280: R1414-R1419, 2001.
27. Yoshiyama M, Roppolo JR, de Groat WC. Alteration by urethane of glutamatergic control of micturition. Eur J Pharmacol 264: 417-425, 1994.
28. Yoshiyama M, Roppolo JR, de Groat WC. Effects of GYKI 52466 and CNQX, AMPA/kainate receptor antagonists, on the micturition reflex in the rat. Brain Res 691: 185-194, 1995.