-
1
-
-
0031454617
-
Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
-
O'Reilly MS, Boehm T, Shing Y, et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997;88:277-285.
-
(1997)
Cell.
, vol.88
, pp. 277-285
-
-
O'Reilly, M.S.1
Boehm, T.2
Shing, Y.3
-
2
-
-
0033575658
-
Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding
-
Yamaguchi N, Anand-Apte B, Lee M, et al. Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding. EMBO J 1999;18:4414-4423.
-
(1999)
EMBO J.
, vol.18
, pp. 4414-4423
-
-
Yamaguchi, N.1
Anand-Apte, B.2
Lee, M.3
-
3
-
-
0031469819
-
Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance
-
Boehm T, Folkman J, Browder T, et al. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 1997;390:404-407.
-
(1997)
Nature
, vol.390
, pp. 404-407
-
-
Boehm, T.1
Folkman, J.2
Browder, T.3
-
4
-
-
0037106261
-
Phase I study of recombinant human endostatin in patients with advanced solid tumors
-
Herbst RS, Hess KR, Tran HT, et al. Phase I study of recombinant human endostatin in patients with advanced solid tumors. J Clin Oncol 2002;20:3792-3803.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 3792-3803
-
-
Herbst, R.S.1
Hess, K.R.2
Tran, H.T.3
-
5
-
-
1642307340
-
Endostatin's antiangiogenic signaling network
-
Abdollahi A, Hahnfeldt P, Maercker C, et al. Endostatin's antiangiogenic signaling network. Mol Cell 2004;13:649-663.
-
(2004)
Mol. Cell.
, vol.13
, pp. 649-663
-
-
Abdollahi, A.1
Hahnfeldt, P.2
Maercker, C.3
-
6
-
-
0035970051
-
Interaction of endostatin with integrins implicated in angiogenesis
-
Rehn M, Veikkola T, Kukk-Valdre E, et al. Interaction of endostatin with integrins implicated in angiogenesis. Proc Natl Acad Sci U S A 2001;98:1024-1029.
-
(2001)
Proc. Natl. Acad. Sci. U S A
, vol.98
, pp. 1024-1029
-
-
Rehn, M.1
Veikkola, T.2
Kukk-Valdre, E.3
-
7
-
-
0035816716
-
Endostatin binds tropomyosin. A potential modulator of the antitumor activity of endostatin
-
MacDonald NJ, Shivers WY, Narum DL, et al. Endostatin binds tropomyosin. A potential modulator of the antitumor activity of endostatin. J Biol Chem 2001;276:25190-25196.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25190-25196
-
-
MacDonald, N.J.1
Shivers, W.Y.2
Narum, D.L.3
-
8
-
-
0035021908
-
Cell surface glypicans are low-affinity endostatin receptors
-
Karumanchi SA, Jha V, Ramchandran R, et al. Cell surface glypicans are low-affinity endostatin receptors. Mol Cell 2001;7:811-822.
-
(2001)
Mol. Cell.
, vol.7
, pp. 811-822
-
-
Karumanchi, S.A.1
Jha, V.2
Ramchandran, R.3
-
9
-
-
0032479999
-
Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin
-
Sasaki T, Fukai N, Mann K, et al. Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin. EMBO J 1998;17:4249-4256.
-
(1998)
EMBO J.
, vol.17
, pp. 4249-4256
-
-
Sasaki, T.1
Fukai, N.2
Mann, K.3
-
10
-
-
0034307327
-
Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase
-
Kim YM, Jang JW, Lee OH, et al. Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase. Cancer Res 2000;60:5410-5413.
-
(2000)
Cancer Res.
, vol.60
, pp. 5410-5413
-
-
Kim, Y.M.1
Jang, J.W.2
Lee, O.H.3
-
11
-
-
35548988483
-
Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin
-
Shi H, Huang Y, Zhou H, et al. Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin. Blood 2007;110:2899-2906.
-
(2007)
Blood
, vol.110
, pp. 2899-2906
-
-
Shi, H.1
Huang, Y.2
Zhou, H.3
-
12
-
-
33646391491
-
The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin
-
Huang Y, Shi H, Zhou H, et al. The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin. Blood 2006;107:3564-3571.
-
(2006)
Blood
, vol.107
, pp. 3564-3571
-
-
Huang, Y.1
Shi, H.2
Zhou, H.3
-
13
-
-
0032754311
-
Molecular dissection of nucleolin's role in growth and cell proliferation: New insights
-
Srivastava M, Pollard HB. Molecular dissection of nucleolin's role in growth and cell proliferation: new insights. FASEB J 1999;13:1911-1922.
-
(1999)
FASEB J.
, vol.13
, pp. 1911-1922
-
-
Srivastava, M.1
Pollard, H.B.2
-
14
-
-
0024966024
-
Major nucleolar proteins shuttle between nucleus and cytoplasm
-
Borer RA, Lehner CF, Eppenberger HM, et al. Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell 1989;56:379-390.
-
(1989)
Cell.
, vol.56
, pp. 379-390
-
-
Borer, R.A.1
Lehner, C.F.2
Eppenberger, H.M.3
-
15
-
-
0344304541
-
Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels
-
Christian S, Pilch J, Akerman ME, et al. Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels. J Cell Biol 2003;163:871-878.
-
(2003)
J. Cell. Biol.
, vol.163
, pp. 871-878
-
-
Christian, S.1
Pilch, J.2
Akerman, M.E.3
-
16
-
-
0035940071
-
The physiology of the lymphatic system
-
Swartz MA. The physiology of the lymphatic system. Adv Drug Deliv Rev 2001;50:3-20.
-
(2001)
Adv. Drug Deliv. Rev.
, vol.50
, pp. 3-20
-
-
Swartz, M.A.1
-
17
-
-
20144369085
-
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
-
Baluk P, Tammela T, Ator E, et al. Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest 2005;115:247-257.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 247-257
-
-
Baluk, P.1
Tammela, T.2
Ator, E.3
-
18
-
-
25444525461
-
Opinion: Emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis
-
Cao Y. Opinion: emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis. Nature Rev Cancer 2005;5:735-743.
-
(2005)
Nature Rev. Cancer
, vol.5
, pp. 735-743
-
-
Cao, Y.1
-
19
-
-
66849128381
-
Lymphangiogenesis in gastric carcinoma correlates with prognosis
-
Gao P, Zhou GY, Zhang QH, et al. Lymphangiogenesis in gastric carcinoma correlates with prognosis. J Pathol 2009;218:192-200.
-
(2009)
J. Pathol.
, vol.218
, pp. 192-200
-
-
Gao, P.1
Zhou, G.Y.2
Zhang, Q.H.3
-
20
-
-
0036306121
-
Vascular growth factors and lymphangiogenesis
-
Jussila L, Alitalo K. Vascular growth factors and lymphangiogenesis. Physiol Rev 2002;82:673-700.
-
(2002)
Physiol. Rev.
, vol.82
, pp. 673-700
-
-
Jussila, L.1
Alitalo, K.2
-
21
-
-
0030026897
-
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
-
Joukov V, Pajusola K, Kaipainen A, et al. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J 1996;15:290-298.
-
(1996)
EMBO J.
, vol.15
, pp. 290-298
-
-
Joukov, V.1
Pajusola, K.2
Kaipainen, A.3
-
22
-
-
64549093353
-
Mechanisms of lymphatic metastasis in human colorectal adenocarcinoma
-
Royston D, Jackson DG. Mechanisms of lymphatic metastasis in human colorectal adenocarcinoma. J Pathol 2009;217:608-619.
-
(2009)
J. Pathol.
, vol.217
, pp. 608-619
-
-
Royston, D.1
Jackson, D.G.2
-
23
-
-
30544452034
-
Hepatocyte growth factor promotes lymphatic vessel formation and function
-
Kajiya K, Hirakawa S, Ma B, et al. Hepatocyte growth factor promotes lymphatic vessel formation and function. EMBO J 2005;24:2885-2895.
-
(2005)
EMBO J.
, vol.24
, pp. 2885-2895
-
-
Kajiya, K.1
Hirakawa, S.2
Ma, B.3
-
24
-
-
20444389049
-
Angiopoietin-1 promotes lymphatic sprouting and hyperplasia
-
Tammela T, Saaristo A, Lohela M, et al. Angiopoietin-1 promotes lymphatic sprouting and hyperplasia. Blood 2005;105:4642-4648.
-
(2005)
Blood
, vol.105
, pp. 4642-4648
-
-
Tammela, T.1
Saaristo, A.2
Lohela, M.3
-
25
-
-
27344431724
-
Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo
-
Bjorndahl M, Cao R, Nissen LJ, et al. Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo. Proc Natl Acad Sci U S A 2005;102:15593- 15598.
-
(2005)
Proc. Natl. Acad. Sci. U S A
, vol.102
, pp. 15593-15598
-
-
Bjorndahl, M.1
Cao, R.2
Nissen, L.J.3
-
26
-
-
11144355004
-
VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment
-
Cursiefen C, Chen L, Borges LP, et al. VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest 2004;113:1040-1050.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 1040-1050
-
-
Cursiefen, C.1
Chen, L.2
Borges, L.P.3
-
27
-
-
5444266254
-
PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis
-
Cao R, Bjorndahl MA, Religa P, et al. PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis. Cancer Cell 2004;6:333-345.
-
(2004)
Cancer Cell.
, vol.6
, pp. 333-345
-
-
Cao, R.1
Bjorndahl, M.A.2
Religa, P.3
-
28
-
-
69949160832
-
Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth
-
Albuquerque RJ, Hayashi T, Cho WG, et al. Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth. Nature Med 2009;15:1023-1030.
-
(2009)
Nature Med.
, vol.15
, pp. 1023-1030
-
-
Albuquerque, R.J.1
Hayashi, T.2
Cho, W.G.3
-
29
-
-
23944516519
-
Endostatin inhibits lymph node metastasis by a down-regulation of the vascular endothelial growth factor C expression in tumor cells
-
Fukumoto S, Morifuji M, Katakura Y, et al. Endostatin inhibits lymph node metastasis by a down-regulation of the vascular endothelial growth factor C expression in tumor cells. Clin Exp Metastasis 2005;22:31-38.
-
(2005)
Clin. Exp. Metastasis
, vol.22
, pp. 31-38
-
-
Fukumoto, S.1
Morifuji, M.2
Katakura, Y.3
-
30
-
-
37549044181
-
Endostatin overexpression inhibits lymphangiogenesis and lymph node metastasis in mice
-
Brideau G, Makinen MJ, Elamaa H, et al. Endostatin overexpression inhibits lymphangiogenesis and lymph node metastasis in mice. Cancer Res 2007;67:11528-11535.
-
(2007)
Cancer Res.
, vol.67
, pp. 11528-11535
-
-
Brideau, G.1
Makinen, M.J.2
Elamaa, H.3
-
31
-
-
0033080517
-
Lymphatic endothelial tumors induced by intraperitoneal injection of incomplete Freund's adjuvant
-
Mancardi S, Stanta G, Dusetti N, et al. Lymphatic endothelial tumors induced by intraperitoneal injection of incomplete Freund's adjuvant. Exp Cell Res 1999;246:368-375.
-
(1999)
Exp. Cell. Res.
, vol.246
, pp. 368-375
-
-
Mancardi, S.1
Stanta, G.2
Dusetti, N.3
-
33
-
-
0025853349
-
Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro
-
Iruela-Arispe ML, Bornstein P, Sage H. Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro. Proc Natl Acad Sci U S A 1991;88:5026-5030.
-
(1991)
Proc. Natl. Acad. Sci. U S A
, vol.88
, pp. 5026-5030
-
-
Iruela-Arispe, M.L.1
Bornstein, P.2
Sage, H.3
-
34
-
-
0037331713
-
Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells
-
Hirakawa S, Hong YK, Harvey N, et al. Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells. Am J Pathol 2003;162:575-586.
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 575-586
-
-
Hirakawa, S.1
Hong, Y.K.2
Harvey, N.3
-
35
-
-
0037008721
-
Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1
-
Kim YM, Hwang S, Pyun BJ, et al. Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1. J Biol Chem 2002;277:27872-27879.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27872-27879
-
-
Kim, Y.M.1
Hwang, S.2
Pyun, B.J.3
-
36
-
-
33646835413
-
Targeting lymphangiogenesis to prevent tumour metastasis
-
Achen MG, Mann GB, Stacker SA. Targeting lymphangiogenesis to prevent tumour metastasis. Br J Cancer 2006;94:1355-1360.
-
(2006)
Br. J. Cancer
, vol.94
, pp. 1355-1360
-
-
Achen, M.G.1
Mann, G.B.2
Stacker, S.A.3
-
37
-
-
33750054757
-
Tumor and lymph node lymphangiogenesis-impact on cancer metastasis
-
Tobler NE, Detmar M. Tumor and lymph node lymphangiogenesis-impact on cancer metastasis. J Leukoc Biol 2006;80:691-696.
-
(2006)
J. Leukoc Biol.
, vol.80
, pp. 691-696
-
-
Tobler, N.E.1
Detmar, M.2
-
39
-
-
34547687853
-
Inhibition of inflammatory lymphangiogenesis by integrin alpha5 blockade
-
Dietrich T, Onderka J, Bock F, et al. Inhibition of inflammatory lymphangiogenesis by integrin alpha5 blockade. Am J Pathol 2007;171:361-372.
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 361-372
-
-
Dietrich, T.1
Onderka, J.2
Bock, F.3
-
40
-
-
67049114117
-
Alpha5beta1 integrin blockade inhibits lymphangiogenesis in airway inflammation
-
Okazaki T, Ni A, Ayeni OA, et al. Alpha5beta1 integrin blockade inhibits lymphangiogenesis in airway inflammation. Am J Pathol 2009;174:2378-2387.
-
(2009)
Am. J. Pathol.
, vol.174
, pp. 2378-2387
-
-
Okazaki, T.1
Ni, A.2
Ayeni, O.A.3
-
41
-
-
0035122537
-
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis
-
Skobe M, Hawighorst T, Jackson DG, et al. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nature Med 2001;7:192-198.
-
(2001)
Nature Med.
, vol.7
, pp. 192-198
-
-
Skobe, M.1
Hawighorst, T.2
Jackson, D.G.3
-
42
-
-
27544483545
-
Tumor-secreted vascular endothelial growth factor-C is necessary for prostate cancer lymphangiogenesis, but lymphangiogenesis is unnecessary for lymph node metastasis
-
Wong SY, Haack H, Crowley D, et al. Tumor-secreted vascular endothelial growth factor-C is necessary for prostate cancer lymphangiogenesis, but lymphangiogenesis is unnecessary for lymph node metastasis. Cancer Res 2005;65:9789-9798.
-
(2005)
Cancer Res.
, vol.65
, pp. 9789-9798
-
-
Wong, S.Y.1
Haack, H.2
Crowley, D.3
-
43
-
-
0037531791
-
Absence of lymphangiogenesis and intratumoural lymph vessels in human metastatic breast cancer
-
Williams CS, Leek RD, Robson AM, et al. Absence of lymphangiogenesis and intratumoural lymph vessels in human metastatic breast cancer. J Pathol 2003;200:195-206.
-
(2003)
J. Pathol.
, vol.200
, pp. 195-206
-
-
Williams, C.S.1
Leek, R.D.2
Robson, A.M.3
-
44
-
-
0036494541
-
Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer
-
Beasley NJ, Prevo R, Banerji S, et al. Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer. Cancer Res 2002;62:1315-1320.
-
(2002)
Cancer Res.
, vol.62
, pp. 1315-1320
-
-
Beasley, N.J.1
Prevo, R.2
Banerji, S.3
-
45
-
-
46049109335
-
Tumor lymphangiogenesis and melanoma metastasis
-
Rinderknecht M, Detmar M. Tumor lymphangiogenesis and melanoma metastasis. J Cell Physiol 2008;216:347-354.
-
(2008)
J. Cell. Physiol.
, vol.216
, pp. 347-354
-
-
Rinderknecht, M.1
Detmar, M.2
-
46
-
-
17144402207
-
VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis
-
Hirakawa S, Kodama S, Kunstfeld R, et al. VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis. J Exp Med 2005;201:1089-1099.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1089-1099
-
-
Hirakawa, S.1
Kodama, S.2
Kunstfeld, R.3
|