Occupational exposures and adverse pregnancy outcomes among nurses: A systematic review and meta-analysis

Journal of Women's Health

Volumn 19, Issue 10, 2010, Pages 1851-1862

  Quansah, Reginald ^a   Jaakkola, Jouni J ^a,b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF OULU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETIC GAS; ANTINEOPLASTIC AGENT; NITROUS OXIDE;

ADVERSE OUTCOME; CLINICAL ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONGENITAL MALFORMATION; CROSS-SECTIONAL STUDY; DENTAL ASSISTANT; EMBASE; HAZARD RATIO; HUMAN; INFERTILITY; LOW BIRTH WEIGHT; MEDLINE; META ANALYSIS; NURSE; NURSE ANESTHETIST; NURSE MIDWIFE; OCCUPATIONAL EXPOSURE; OPERATING ROOM PERSONNEL; PREGNANCY OUTCOME; PREMATURITY; PRIORITY JOURNAL; REVIEW; RISK; SHIFT WORKER; SPONTANEOUS ABORTION; SYSTEMATIC REVIEW;

ABORTION, SPONTANEOUS; ANESTHETICS, INHALATION; ANTINEOPLASTIC AGENTS; CONGENITAL ABNORMALITIES; EPIDEMIOLOGIC STUDIES; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; NURSING STAFF; OCCUPATIONAL EXPOSURE; PREGNANCY; PREGNANCY OUTCOME; WOMEN, WORKING; WORK SCHEDULE TOLERANCE;

EID: 77957984925     PISSN: 15409996     EISSN: None     Source Type: Journal    
DOI: 10.1089/jwh.2009.1876     Document Type: Review

References (72)

1. World Health organization: Statistics on health workforce demographics. Available at apps.who.int/globalatlas/default. asp
2. Axelsson G, Rylander R, Molin I. Outcome of pregnancy in relation to irregular and inconvenient work schedules. Br J Ind Med 1989;46:393-398.
3. Axelsson G, Ahlborg G Jr, Bodin L. Shift work, nitrous oxide exposure, and spontaneous abortion among Swedish midwives. Occup Environ Med 1996;53:374-378. (Pubitemid 26198390)
4. Saurel-Cubizolles MJ, Hays M, Estryn-Behar M. Work in operating rooms and pregnancy outcome among nurses. Int Arch Occup Environ Health 1994;66:235-241.
5. Saurel-Cubizolles MJ, Kaminski M, Llado-Arkhipoff J, et al. Pregnancy and its outcome among hospital personnel according to occupation and working conditions. J Epidemiol Community Health 1985;39:129-134.
6. Lindbohm ML. Effects of parental exposure to solvents on pregnancy outcome. J Occup Environ Med 1995;37:908-914.
7. Ahlborg G Jr, Hemminki K. Reproductive effects of chemical exposures in health professions. J Occup Environ Med 1995;37:957-961.
8. Ekblad U. Biological agents and pregnancy. J Occup Environ Med 1995;37:962-965.
9. Corbett TH, Cornell RG, Endres JL, Lieding K. Birth defects among children of nurse-anesthetists. Anesthesiology 1974;41:341-344.
10. Skov T, Maarup B, Olsen J, Rørth M, Winthereik H, Lynge E. Leukaemia and reproductive outcome among nurses handling antineoplastic drugs. Br J Ind Med 1992;49:855-861.
11. Cohen EN, Bellville JW, Brown BW Jr. Anesthesia, pregnancy, and miscarriage: A study of operating room nurses and anesthetists. Anesthesiology 1971;35:343-347.
12. Rosenberg P, Kirves A. Miscarriages among operating theatre staff. Acta Anaesthesiol Scand 1973;53:37-42.
13. Fransman W, Roeleveld N, Peelen S, de Kort W, Kromhout H, Heederik D. Nurses with dermal exposure to antineoplastic drugs: Reproductive outcomes. Epidemiology 2007; 18:112-119. (Pubitemid 46019618)
14. Medkova J. On the problems of agents with mutagenic and carcinogenic effects in health care. Cytostatic drugs. Acta Univ Palacki Olomuc Fac Med 1990;126:107-115.
15. Bodin L, Axelsson G, Ahlborg G Jr. The association of shift work and nitrous oxide exposure in pregnancy with birth weight and gestational age Epidemiology 1999;10:429-436.
16. Figa-Talamanca I. Reproductive problems among women healthcare workers: Epidemiologic evidence and preventive strategies. Epidemiol Rev. 2000;22:249-260.
17. Ahlborg G Jr, Hemminki K. Reproductive effects of chemical exposures in health professions. J Occup Environ Med 1995;37:957-961.
18. Olfert SM. Reproductive outcomes among dental personnel: A review of selected exposures. J Can Dent Assoc 2006;72: 821-825.
19. Boivin JF. Risk of spontaneous abortion in women occupationally exposed to anaesthetic gases: A meta-analysis. Occup Environ Med 1997;54:541-548.
20. Dranitsaris G, Johnston M, Poirier S, et al. Are health care providers who work with cancer drugs at an increased risk for toxic events? A systematic review and meta-analysis of the literature. J Oncol Pharm Pract 2005;11:69-78.
21. Buring JE, Hennekens CH, Mayrent SL, Rosner B, Greenberg ER, Colton T. Health experiences of operating room personnel. Anesthesiology 1985;62:325-330.
22. von Elm E, Altman DG, Egger M, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies. Lancet 2007;370:1453-1457.
23. Wells GA, Shea B, O'Connell D, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Available at www.ohri.ca/programs/ clinical-epidemiology/oxford.htm
24. Roffey DM, Wai EK, Bishop P, et al. Causal assessment of awkward occupational postures and low back pain Results of a systematic review. Spine J 2010;10:89-99.
25. Jaakkola JJ, Ahmed P, Ieromnimon A, et al. Preterm delivery and asthma: A systematic review and meta-analysis. J Allergy Clin Immunol 2006;118:823-830.
26. Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959;22:719-748.
27. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7:177-188.
28. Petitte DB. Approaches to heterogeneity in meta-analysis. Stat Med 2001;20:3625-3633.
29. Higgins JP, Thompson S. Quantifying heterogeneity in a meta-analysis. Stat Med 2002;21:1539-1558.
30. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:625-634.
31. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometries 1994;50: 1088-1101.
32. Stata Corporation. Stata statistical software, release 10. College Station, TX: Stata Corporation, 2005.
33. Axelsson G, Rylander R. Exposure to anaesthetic gases and spontaneous abortion: Response bias in a postal questionnaire study. Int J Epidemiol 1982;11:250-256.
34. Ericson A, Källen B. Pregnancy outcome in women working as dentists, dental assistants or dental technicians. Int Arch Occup Environ Health 1989;61:329-333.
35. Guirguis SS, Pelmear PL, Roy ML, Wong L. Health effects associated with exposure to anaesthetic gases in Ontario hospital personnel. Br Ind Med 1990;47:490-497.
36. Ericson A, Kallen. Survey of infants born in 1973 or 1975 to Swedish women working in operating rooms during pregnancies. Anesth Analg 1979;58:302-305.
37. Heidam LZ. Spontaneous abortions among dental assistants, factory workers, painters, and gardening workers: A followup study. J Epidemiol Community Health 1984; 38:149-155.
38. Lauwerys R, Siddons M, Misson CB, et al. Anaesthetic health hazards among Belgian nurses and physicians. Int Arch Occup Environ Health 1981;48:195-203.
39. Ericson HA, Källen AJ. Hospitalization for miscarriage and delivery outcome among Swedish nurses working in operating rooms 1973-1978. Anesth Analg 1985;64:981-988.
40. Whelan EA, Lawson CC, Grajewski B. Work schedule during pregnancy and spontaneous abortion. Epidemiology 2007;18:350-355.
41. Rowland AS, Baird DD, Shore DL, Weinberg CR, Savitz DA, Wilcox AJ. Nitrous oxide and spontaneous abortion in female dental assistants. Am J Epidemiol 1995;141:531-538.
42. Stucker I, Caillard JF, Collin R, Gout M, Poyen D, Hemon D. Risk of spontaneous abortion among nurses handling antineoplastic drugs. Scand J Work Environ Health 1990;16:102-107.
43. McAbee RR, Gallucci BJ, Checkoway H. Adverse reproductive outcomes and occupational exposures among nurses: An investigation of multiple hazardous exposures. AAOHN J 1993;41:110-119.
44. Cohen EN, Gift HC, Brown BW, et al. Occupational disease in dentistry and chronic exposure to trace anesthetic gases. J Am Dent Assoc 1980;101:21-31.
45. American Society of Anesthesiologists. Report of Ad Hoc Committe. Effect of trace anesthetics on the health of operating room personnel. Anesthesiology 1974;41:321-340.
46. Hemminki K, Kyyrönen P, Lindbohm ML. Spontaneous abortions and malformations in the offspring of nurses exposed to anaesthetic gases, cytostatic drugs, and other potential hazards in hospitals, based on registered information of outcome. J Epidemiol Community Health 1985;39:141-147.
47. Matte TD, Mulinare J, Erickson JD. Case-control study of congenital defects and parental employment in health care. Am J Ind Med 1993;24:11-23.
48. Saurel-Cubizolles MJ, Job-Spira N, Estryn-Behar M. Ectopic pregnancy and occupational exposure to antineoplastic drugs. Lancet 1993;341:1169-1171.
49. Luke B, Mamelle N, Keith L. The association between occupational factors and preterm birth: A United States nurses' study. Research Committe of the Association of the Women's Health, Obstetric, and Neonatal Nurses. Am J Obstet Gynecol 1995;173:849-862.
50. Lawson CC,Whelan EA, Hibert EN, Grajewski B, Spiegelman D, Rich-Edwards JW. Occupational factors and the risk of preterm birth in nurses. Am J Obstet Gynecol 2009;200:e1-8.
51. Simcox AA, Jaakkola JJ. Does work as a nurse increase the risk of adverse pregnancy outcomes? J Occup Environ Med 2008;50:590-592.
52. Katz VL, Miller NH, Bowes WA Jr. Pregnancy complications of physicians. West J Med 1988;149:704-707.
53. Grunebaum A, Minkoff H, Blake D. Pregnancy among obstetricians: A comparison of births before, during, and after residency. Am J Obstet Gynecol 1987;157:79-83.
54. Pinhas-Hamiel O, Rotstein Z, Achiron A, et al. Pregnancy during residency-An Israeli survey of women physicians. Health Care Women Int 1999;20:63-70.
55. Osborn LM, Harris DL, Reading JC, Prather MB. Outcome of pregnancies experienced during residency. J Fam Pract 1990; 31:618-622.
56. Miller NH, Katz VL, Cefalo RC. Pregnancies among physicians. A historical cohort study. J Reprod Med 1989;34:790-796.
57. Schwartz RW. Pregnancy in physicians: Characteristics and complications Obstet Gynecol 1985;66:672-676.
58. Phelan ST. Pregnancy during residency: I. The decision "to be or not to be". Obstet Gynecol 1988;72:425-431.
59. Gabbe SG, Morgan MA, Power ML, Schulkin J, Williams SB. Duty hours and pregnancy outcome among residents in obstetrics and gynecology. Obstet Gynecol 2003;102:948-951.
60. Klebanoff MA, Shiono PH, Rhoads GG. Outcomes of pregnancy in a national sample of resident physicians. N Engl J Med 1990;323:1040-1045.
61. Heinonen S, Saarikoski S. Reproductive risk factors, pregnancy characteristics and obstetric outcome in female doctors. Br J Obstet Gynaecol 2002;109:261-264.
62. Seneviratne SR, Fernando DN. Influence of work on pregnancy outcome. Int J Gynaecol Obstet 1994;45:35-40.
63. Ortayli N, Ozugurlu M, Gokcay G. Female health workers: An obstetric risk group. Int J Gynaecol Obstet 1996;54:263-270.
64. Whelan EA, Lawson CC, Grajewski B, Hibert EN, Spiegelman D, Rich-Edwards JW. Work schedule during pregnancy and spontaneous abortion. Epidemiology 2007;18:350-355.
65. Koemeester AP, Broersen JP, Treffers PE. Physical work load and gestational age at delivery. Occup Environ Med 1995;52:313-315.
66. Valanis B, Vollmer WM, Steele P. Occupational exposure to antineoplastic agents: Self-reported miscarriages and stillbirths among nurses and pharmacists. J Occup Environ Med 1999;41:632-638.
67. Selevan SG, Lemasters GK. The dose-response fallacy in human reproductive studies of toxic exposures. J Occup Med 1987;29:451-454.
68. Klebanoff MA, Shiono PH, Rhoads GG. Spontaneous and induced abortion among resident physicians. JAMA 1991;265:2821-2825.
69. Savitz DA, Hertz-Picciotto I, Poole C, Olshan AF. Epidemiologic measures of the course and outcome of pregnancy. Epidemiol Rev 2002;24:91-101.
70. Hertz-Picciotto I, Pastore LM, Beaumont JJ. Timing and patterns of exposures during pregnancy and their implications for study methods. Epidemiology 1996;143:597-607.
71. Hinckley AF, Bachand AM, Reif JS. Late pregnancy exposures to disinfectant by-products and growth-related birth outcomes. Environ Health Perspect 2005;113:1808-1813.
72. Shaw GM, Gold EB. Methodological considerations in the study of parental occupational exposures and congenital malformations in the offspring. Scand J Work Environ Health 1988;14:344-355.